What Is the AMPK Pathway? AMPK is the main metabolic pathways activated by fasting and supports energy generation, fat breakdown, a healthy inflammatory response, and normal glucose levels and insulin activity. It supports longevity by increasing autophagy, which cleans out old and damaged cells to make room for new, healthy cells†.

Access the Body’s Fat Stores – The AMPK pathway helps your body access fat stores, turning fat into ketones. AMPK Charge+™ facilitates this process by flipping your master “metabolic switch” from burning primarily sugar for energy to fat†.

Use Alone or With Fasting – This bioavailable blend of DIM, quercetin, milk thistle, resveratrol, berberine, and cinnamon is safe to take daily and complements intermittent fasting and keto or carb-restricted diets (and may allow for more flexible fasting protocols).

Resveratrol – Resveratrol is a fasting mimetic phytocompound that has been shown to stimulate AMPK, activate sirtuins, and support autophagy. Resveratrol works synergistically with cellular NAD+ and mitochondrial biogenesis, supporting robust cellular energy production.

Berberine – Berberine is a bioactive compound, best known for supporting healthy blood sugar metabolism. Berberine supports AMPK activation and aids in safeguarding the liver by supporting healthy fat breakdown.

Quercetin – Quercetin is a versatile fasting mimetic phytonutrient that has been shown to support several aspects of metabolism and healthy aging. It is a powerful antioxidant due to its role in AMPK activation. Research shows that quercetin supports mitochondrial biogenesis and is a powerful immune-modulating compound. It has been well studied as a senolytic supporting healthy cellular senescence.

Milk Thistle – Milk Thistle, or Silybum marianum, is a revered member of the traditional herbal medicine compendium. Silymarin, a group of active phytochemicals in milk thistle, supports AMPK activity and has been shown to restore healthy NAD+ levels in the liver.

Diindolylmethane (DIM) – DIM is a compound derived from indole-3-carbinol, which is found in cruciferous vegetables. DIM has been shown to influence healthy gene expression by activating AMPK. It also plays a role in supporting a healthy immune response and the upregulation of detoxification pathways.

Cinnamon – Cinnamon bark oil is a warming, aromatic essential oil derived from Cinnamomum cassia bark. Cinnamon has been shown to activate AMPK, support healthy lipid levels, help regulate blood sugar, and have cardio-protective properties.

Use Alone or With Fasting – This formula complements intermittent fasting and keto or carb-restricted diets (and may allow for more flexible fasting protocols).