{"product_id":"1-mna-apigenin-30-capsules-nubioage","title":"1-MNA + Apigenin 30 capsules nuBioAge","description":"\u003csection class=\"product-description\"\u003e\n  \u003ch2\u003eOverview\u003c\/h2\u003e\n\n  \u003cp\u003e\u003cstrong\u003e1-MNA + Apigenin 30 Capsules by nuBioAge\u003c\/strong\u003e is an advanced dual-ingredient supplement formulated to support \u003cstrong\u003evascular health, NAD+ metabolism, cellular energy, and healthy aging\u003c\/strong\u003e. Each vegetarian capsule combines \u003cstrong\u003e250 mg of 1-MNA (1-methylnicotinamide chloride)\u003c\/strong\u003e with \u003cstrong\u003e150 mg of apigenin standardized to 98%\u003c\/strong\u003e.\u003c\/p\u003e\n\n  \u003cp\u003eThe formula brings together two compounds associated with complementary biological pathways. \u003cstrong\u003e1-MNA\u003c\/strong\u003e is a naturally occurring metabolite of nicotinamide investigated for its relationship with vascular function, circulation, and inflammatory signaling. \u003cstrong\u003eApigenin\u003c\/strong\u003e is a naturally occurring plant flavonoid studied for its ability to influence CD38, an enzyme involved in the metabolism and breakdown of NAD+.\u003c\/p\u003e\n\n  \u003cp\u003eBy combining vascular and metabolic support with ingredients associated with NAD+ preservation, nuBioAge offers a targeted formula for adults interested in cellular resilience, healthy longevity, and maintaining normal physiological function with age.\u003c\/p\u003e\n\n  \u003cp\u003eEach bottle contains \u003cstrong\u003e30 vegetarian capsules\u003c\/strong\u003e, providing \u003cstrong\u003e30 daily servings\u003c\/strong\u003e or a one-month supply when taken as directed.\u003c\/p\u003e\n\n  \u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\n  \u003cul\u003e\n    \u003cli\u003eProvides 250 mg of 1-MNA per capsule\u003c\/li\u003e\n    \u003cli\u003eContains 150 mg of apigenin standardized to 98% purity\u003c\/li\u003e\n    \u003cli\u003eSupports healthy vascular function and circulation\u003c\/li\u003e\n    \u003cli\u003eSupports normal endothelial function and vascular wellness\u003c\/li\u003e\n    \u003cli\u003eFeatures compounds investigated for their roles in NAD+ metabolism\u003c\/li\u003e\n    \u003cli\u003eApigenin is studied for its ability to inhibit CD38 activity\u003c\/li\u003e\n    \u003cli\u003eSupports cellular health and normal energy metabolism\u003c\/li\u003e\n    \u003cli\u003eSupports a balanced inflammatory response\u003c\/li\u003e\n    \u003cli\u003eProvides antioxidant-related cellular support through apigenin\u003c\/li\u003e\n    \u003cli\u003eCombines two complementary compounds in one capsule\u003c\/li\u003e\n    \u003cli\u003eDesigned for healthy aging and longevity-focused nutritional routines\u003c\/li\u003e\n    \u003cli\u003eConvenient once-daily serving\u003c\/li\u003e\n    \u003cli\u003eVegetarian capsule formulation\u003c\/li\u003e\n    \u003cli\u003e30 capsules per bottle\u003c\/li\u003e\n  \u003c\/ul\u003e\n\n  \u003ch2\u003eSupplement Facts\u003c\/h2\u003e\n\n  \u003cp\u003e\u003cstrong\u003eServing Size:\u003c\/strong\u003e 1 Capsule\u003c\/p\u003e\n  \u003cp\u003e\u003cstrong\u003eServings Per Container:\u003c\/strong\u003e 30\u003c\/p\u003e\n\n  \u003ctable\u003e\n    \u003cthead\u003e\n      \u003ctr\u003e\n        \u003cth\u003eIngredient\u003c\/th\u003e\n        \u003cth\u003eAmount Per Serving\u003c\/th\u003e\n        \u003cth\u003e% Daily Value\u003c\/th\u003e\n      \u003c\/tr\u003e\n    \u003c\/thead\u003e\n    \u003ctbody\u003e\n      \u003ctr\u003e\n        \u003ctd\u003e1-MNA (1-Methylnicotinamide Chloride)\u003c\/td\u003e\n        \u003ctd\u003e250 mg\u003c\/td\u003e\n        \u003ctd\u003e†\u003c\/td\u003e\n      \u003c\/tr\u003e\n      \u003ctr\u003e\n        \u003ctd\u003eApigenin (98%)\u003c\/td\u003e\n        \u003ctd\u003e150 mg\u003c\/td\u003e\n        \u003ctd\u003e†\u003c\/td\u003e\n      \u003c\/tr\u003e\n    \u003c\/tbody\u003e\n  \u003c\/table\u003e\n\n  \u003cp\u003e\u003cstrong\u003e† Daily Value (DV) not established.\u003c\/strong\u003e\u003c\/p\u003e\n\n  \u003cp\u003e\u003cstrong\u003eOther Ingredients:\u003c\/strong\u003e Hypromellose (vegetable capsule), microcrystalline cellulose, magnesium stearate, silicon dioxide.\u003c\/p\u003e\n\n  \u003ch2\u003eIngredient Breakdown\u003c\/h2\u003e\n\n  \u003ctable\u003e\n    \u003cthead\u003e\n      \u003ctr\u003e\n        \u003cth\u003eIngredient\u003c\/th\u003e\n        \u003cth\u003eAmount\u003c\/th\u003e\n        \u003cth\u003eFunction in the Formula\u003c\/th\u003e\n      \u003c\/tr\u003e\n    \u003c\/thead\u003e\n    \u003ctbody\u003e\n      \u003ctr\u003e\n        \u003ctd\u003e1-MNA (1-Methylnicotinamide Chloride)\u003c\/td\u003e\n        \u003ctd\u003e250 mg\u003c\/td\u003e\n        \u003ctd\u003eA naturally occurring nicotinamide metabolite investigated for its relationship with endothelial function, vascular signaling, circulation, and inflammatory balance.\u003c\/td\u003e\n      \u003c\/tr\u003e\n      \u003ctr\u003e\n        \u003ctd\u003eApigenin (98%)\u003c\/td\u003e\n        \u003ctd\u003e150 mg\u003c\/td\u003e\n        \u003ctd\u003eA plant-derived flavonoid studied for its effects on CD38 activity, NAD+ metabolism, antioxidant pathways, and cellular signaling.\u003c\/td\u003e\n      \u003c\/tr\u003e\n      \u003ctr\u003e\n        \u003ctd\u003eHypromellose\u003c\/td\u003e\n        \u003ctd\u003eNot specified\u003c\/td\u003e\n        \u003ctd\u003ePlant-derived material used to produce the vegetarian capsule.\u003c\/td\u003e\n      \u003c\/tr\u003e\n      \u003ctr\u003e\n        \u003ctd\u003eMicrocrystalline Cellulose\u003c\/td\u003e\n        \u003ctd\u003eNot specified\u003c\/td\u003e\n        \u003ctd\u003eFormulation ingredient that supports consistent capsule filling.\u003c\/td\u003e\n      \u003c\/tr\u003e\n      \u003ctr\u003e\n        \u003ctd\u003eMagnesium Stearate\u003c\/td\u003e\n        \u003ctd\u003eNot specified\u003c\/td\u003e\n        \u003ctd\u003eManufacturing excipient used to support ingredient flow and capsule production.\u003c\/td\u003e\n      \u003c\/tr\u003e\n      \u003ctr\u003e\n        \u003ctd\u003eSilicon Dioxide\u003c\/td\u003e\n        \u003ctd\u003eNot specified\u003c\/td\u003e\n        \u003ctd\u003eAnti-caking agent that helps maintain powder flow and formulation consistency.\u003c\/td\u003e\n      \u003c\/tr\u003e\n    \u003c\/tbody\u003e\n  \u003c\/table\u003e\n\n  \u003ch2\u003eHow 1-MNA + Apigenin Works\u003c\/h2\u003e\n\n  \u003cp\u003eThe concept behind \u003cstrong\u003enuBioAge 1-MNA + Apigenin\u003c\/strong\u003e is to combine compounds involved in two interconnected areas of healthy aging: \u003cstrong\u003evascular function and NAD+ metabolism\u003c\/strong\u003e.\u003c\/p\u003e\n\n  \u003cp\u003e1-MNA is formed naturally during the metabolism of nicotinamide, a form of vitamin B3. This metabolite has been investigated for its biological activity in vascular tissues, including pathways related to endothelial signaling and inflammatory responses.\u003c\/p\u003e\n\n  \u003cp\u003eApigenin is a bioactive flavonoid found in various plants. Laboratory research has investigated its ability to inhibit CD38, an enzyme that consumes NAD+ during normal cellular metabolism.\u003c\/p\u003e\n\n  \u003cp\u003eNAD+ is an essential coenzyme involved in cellular energy production, metabolic reactions, and cellular signaling. Because NAD+ availability is connected with numerous aspects of cell function, the enzymes responsible for its production and consumption are important research targets.\u003c\/p\u003e\n\n  \u003cp\u003eCombining 1-MNA and apigenin offers a nutritional approach focused on vascular wellness alongside NAD+-related cellular pathways. However, the clinical effects of this exact combination have not been established through the product information supplied by the manufacturer.\u003c\/p\u003e\n\n  \u003ch2\u003eWhat Is 1-MNA?\u003c\/h2\u003e\n\n  \u003cp\u003e\u003cstrong\u003e1-MNA\u003c\/strong\u003e, also known as \u003cstrong\u003e1-methylnicotinamide\u003c\/strong\u003e or \u003cstrong\u003eN1-methylnicotinamide\u003c\/strong\u003e, is a naturally occurring metabolite formed during nicotinamide metabolism.\u003c\/p\u003e\n\n  \u003cp\u003eIn the body, nicotinamide N-methyltransferase (NNMT) participates in converting nicotinamide into 1-MNA. The compound can then undergo further metabolism into downstream metabolites.\u003c\/p\u003e\n\n  \u003cp\u003eAlthough 1-MNA is produced during vitamin B3 metabolism, it is not the same compound as nicotinamide, nicotinamide riboside (NR), or nicotinamide mononucleotide (NMN).\u003c\/p\u003e\n\n  \u003cp\u003eScientific interest in 1-MNA includes its potential biological activity beyond its role as a metabolic intermediate. Experimental and clinical research has examined associations with endothelial function, vascular physiology, prostacyclin-related signaling, and inflammatory pathways.\u003c\/p\u003e\n\n  \u003cp\u003eThese areas make 1-MNA of interest to researchers studying cardiovascular wellness, cellular metabolism, and healthy aging.\u003c\/p\u003e\n\n  \u003ch2\u003e1-MNA and Vascular Health\u003c\/h2\u003e\n\n  \u003cp\u003eThe vascular endothelium is a thin layer of cells lining the interior surface of blood vessels. It plays an important role in maintaining vascular tone, normal circulation, and communication between the bloodstream and surrounding tissues.\u003c\/p\u003e\n\n  \u003cp\u003eHealthy endothelial function is supported by complex signaling pathways that help regulate vessel relaxation, blood flow, and normal vascular responses.\u003c\/p\u003e\n\n  \u003cp\u003e1-MNA has been investigated for its involvement in vascular biology, including pathways associated with endothelial signaling and prostacyclin activity.\u003c\/p\u003e\n\n  \u003cp\u003eProstacyclin is a naturally occurring signaling molecule involved in the regulation of vascular tone and platelet function. Research into 1-MNA has explored how this metabolite may interact with related vascular processes.\u003c\/p\u003e\n\n  \u003cp\u003enuBioAge includes 250 mg of 1-MNA per capsule as the vascular-support component of the formula.\u003c\/p\u003e\n\n  \u003cp\u003e\u003cstrong\u003eImportant:\u003c\/strong\u003e This supplement is intended for nutritional support and is not a substitute for prescribed cardiovascular medication or medical treatment.\u003c\/p\u003e\n\n  \u003ch2\u003eWhat Is Apigenin?\u003c\/h2\u003e\n\n  \u003cp\u003e\u003cstrong\u003eApigenin\u003c\/strong\u003e is a naturally occurring flavonoid found in several plants and foods.\u003c\/p\u003e\n\n  \u003cp\u003eDietary sources of apigenin include:\u003c\/p\u003e\n\n  \u003cul\u003e\n    \u003cli\u003eParsley\u003c\/li\u003e\n    \u003cli\u003eChamomile\u003c\/li\u003e\n    \u003cli\u003eCelery\u003c\/li\u003e\n    \u003cli\u003eVarious herbs and plant foods\u003c\/li\u003e\n  \u003c\/ul\u003e\n\n  \u003cp\u003eApigenin belongs to the flavone subclass of flavonoids and has been studied for its antioxidant-related properties and interactions with cellular signaling pathways.\u003c\/p\u003e\n\n  \u003cp\u003eOne area of particular interest is its potential influence on \u003cstrong\u003eCD38\u003c\/strong\u003e, an enzyme involved in NAD+ consumption.\u003c\/p\u003e\n\n  \u003cp\u003enuBioAge uses \u003cstrong\u003e150 mg of apigenin standardized to 98%\u003c\/strong\u003e per capsule. This provides a clearly identified quantity of the active flavonoid rather than relying on an unspecified amount from a general botanical extract.\u003c\/p\u003e\n\n  \u003ch2\u003eApigenin and CD38 Inhibition\u003c\/h2\u003e\n\n  \u003cp\u003e\u003cstrong\u003eCD38\u003c\/strong\u003e is an enzyme involved in several biological processes, including the metabolism of NAD+ and the generation of signaling molecules.\u003c\/p\u003e\n\n  \u003cp\u003eBecause CD38 consumes NAD+, its activity is relevant to research exploring cellular NAD+ availability and metabolism.\u003c\/p\u003e\n\n  \u003cp\u003eExperimental studies have identified apigenin as a compound capable of inhibiting CD38 activity under certain laboratory conditions.\u003c\/p\u003e\n\n  \u003cp\u003eThis has led to interest in apigenin as a potential nutritional ingredient for supporting NAD+-related biological pathways.\u003c\/p\u003e\n\n  \u003cp\u003eHowever, it is important to distinguish laboratory findings from proven effects in humans. The ability of oral apigenin supplementation at a particular dose to meaningfully inhibit CD38 or preserve NAD+ in humans has not been conclusively established.\u003c\/p\u003e\n\n  \u003cp\u003eThe manufacturer positions apigenin as the NAD+ preservation component of this formula, complementing the vascular-related activity of 1-MNA.\u003c\/p\u003e\n\n  \u003ch2\u003eUnderstanding NAD+ and Cellular Energy\u003c\/h2\u003e\n\n  \u003cp\u003e\u003cstrong\u003eNAD+\u003c\/strong\u003e, or nicotinamide adenine dinucleotide, is an essential coenzyme found throughout the body.\u003c\/p\u003e\n\n  \u003cp\u003eIt participates in oxidation-reduction reactions that help cells convert nutrients into usable energy and supports numerous other cellular functions.\u003c\/p\u003e\n\n  \u003cp\u003eNAD+ is also used by enzymes involved in cellular signaling and maintenance, including certain sirtuins, PARPs, and CD38.\u003c\/p\u003e\n\n  \u003cp\u003eNormal NAD+ metabolism depends on maintaining a balance between its synthesis, recycling, and consumption.\u003c\/p\u003e\n\n  \u003cp\u003eResearch into healthy aging increasingly examines how these processes change with age and how they interact with mitochondrial function, metabolic regulation, and cellular resilience.\u003c\/p\u003e\n\n  \u003cp\u003eRather than providing NMN or NR directly, nuBioAge 1-MNA + Apigenin features compounds associated with vascular biology and NAD+ metabolism through different pathways.\u003c\/p\u003e\n\n  \u003ch2\u003eNAD+ Preservation vs. NAD+ Precursor Supplementation\u003c\/h2\u003e\n\n  \u003cp\u003eNot all supplements marketed for NAD+ support work through the same biological mechanisms.\u003c\/p\u003e\n\n  \u003cp\u003e\u003cstrong\u003eNAD+ precursors\u003c\/strong\u003e, such as NMN and nicotinamide riboside, participate in pathways that the body uses to synthesize NAD+.\u003c\/p\u003e\n\n  \u003cp\u003e\u003cstrong\u003eCD38-related approaches\u003c\/strong\u003e focus on enzymes involved in NAD+ consumption. Apigenin is of interest in this category because laboratory research has investigated its effects on CD38 activity.\u003c\/p\u003e\n\n  \u003cp\u003e\u003cstrong\u003e1-MNA\u003c\/strong\u003e is different from both categories. It is a metabolite of nicotinamide with biological activity investigated in vascular and metabolic research.\u003c\/p\u003e\n\n  \u003ctable\u003e\n    \u003cthead\u003e\n      \u003ctr\u003e\n        \u003cth\u003eCompound\u003c\/th\u003e\n        \u003cth\u003ePrimary Biological Connection\u003c\/th\u003e\n        \u003cth\u003eResearch Interest\u003c\/th\u003e\n      \u003c\/tr\u003e\n    \u003c\/thead\u003e\n    \u003ctbody\u003e\n      \u003ctr\u003e\n        \u003ctd\u003e1-MNA\u003c\/td\u003e\n        \u003ctd\u003eNicotinamide metabolism\u003c\/td\u003e\n        \u003ctd\u003eVascular function, endothelial signaling, and inflammatory pathways\u003c\/td\u003e\n      \u003c\/tr\u003e\n      \u003ctr\u003e\n        \u003ctd\u003eApigenin\u003c\/td\u003e\n        \u003ctd\u003eFlavonoid signaling and CD38 interaction\u003c\/td\u003e\n        \u003ctd\u003eNAD+ consumption pathways and cellular signaling\u003c\/td\u003e\n      \u003c\/tr\u003e\n      \u003ctr\u003e\n        \u003ctd\u003eNMN\u003c\/td\u003e\n        \u003ctd\u003eNAD+ biosynthesis precursor\u003c\/td\u003e\n        \u003ctd\u003eSupporting cellular NAD+ production\u003c\/td\u003e\n      \u003c\/tr\u003e\n      \u003ctr\u003e\n        \u003ctd\u003eNicotinamide Riboside (NR)\u003c\/td\u003e\n        \u003ctd\u003eNAD+ biosynthesis precursor\u003c\/td\u003e\n        \u003ctd\u003eSupporting cellular NAD+ production\u003c\/td\u003e\n      \u003c\/tr\u003e\n    \u003c\/tbody\u003e\n  \u003c\/table\u003e\n\n  \u003cp\u003eThese compounds have different biochemical characteristics and should not be considered interchangeable on a milligram-for-milligram basis.\u003c\/p\u003e\n\n  \u003ch2\u003e1-MNA, Apigenin, and Healthy Aging\u003c\/h2\u003e\n\n  \u003cp\u003eHealthy aging involves maintaining the function of interconnected physiological systems, including the cardiovascular system, cellular energy pathways, and the body's ability to respond to normal metabolic demands.\u003c\/p\u003e\n\n  \u003cp\u003eThe ingredients in nuBioAge 1-MNA + Apigenin reflect two areas of interest in longevity research:\u003c\/p\u003e\n\n  \u003cul\u003e\n    \u003cli\u003e\n\u003cstrong\u003eVascular resilience:\u003c\/strong\u003e maintaining normal endothelial function and circulation.\u003c\/li\u003e\n    \u003cli\u003e\n\u003cstrong\u003eCellular metabolism:\u003c\/strong\u003e understanding and supporting biological pathways associated with NAD+ availability.\u003c\/li\u003e\n  \u003c\/ul\u003e\n\n  \u003cp\u003eThe formula is designed for adults interested in nutritional support for these systems as part of an overall healthy lifestyle.\u003c\/p\u003e\n\n  \u003cp\u003eAlthough 1-MNA and apigenin are subjects of scientific investigation, current evidence does not establish that taking this combination extends human lifespan or reverses biological aging.\u003c\/p\u003e\n\n  \u003ch2\u003eAntioxidant and Inflammatory Response Support\u003c\/h2\u003e\n\n  \u003cp\u003eOxidative stress and inflammatory signaling are normal parts of cellular physiology. Maintaining an appropriate balance is important for healthy tissue function.\u003c\/p\u003e\n\n  \u003cp\u003eApigenin has been studied for its interactions with antioxidant-related and inflammatory signaling pathways.\u003c\/p\u003e\n\n  \u003cp\u003e1-MNA has also been investigated for biological activity relevant to vascular and inflammatory responses.\u003c\/p\u003e\n\n  \u003cp\u003eThese properties are part of the scientific rationale for combining the ingredients, although the degree to which the finished product influences these pathways in humans has not been established.\u003c\/p\u003e\n\n  \u003ch2\u003eWhy Choose 1-MNA + Apigenin by nuBioAge?\u003c\/h2\u003e\n\n  \u003cp\u003eUnlike single-ingredient formulations, nuBioAge 1-MNA + Apigenin combines two clearly dosed compounds that participate in different aspects of cellular physiology.\u003c\/p\u003e\n\n  \u003cp\u003eThe formula provides:\u003c\/p\u003e\n\n  \u003cul\u003e\n    \u003cli\u003e\n\u003cstrong\u003e250 mg 1-MNA:\u003c\/strong\u003e a naturally occurring nicotinamide metabolite studied in vascular and metabolic research.\u003c\/li\u003e\n    \u003cli\u003e\n\u003cstrong\u003e150 mg apigenin (98%):\u003c\/strong\u003e a standardized plant flavonoid investigated for CD38-related activity.\u003c\/li\u003e\n    \u003cli\u003e\n\u003cstrong\u003eOne-capsule daily serving:\u003c\/strong\u003e a convenient format for consistent supplementation.\u003c\/li\u003e\n    \u003cli\u003e\n\u003cstrong\u003eVegetarian capsule:\u003c\/strong\u003e made with plant-derived hypromellose.\u003c\/li\u003e\n    \u003cli\u003e\n\u003cstrong\u003eTransparent Supplement Facts:\u003c\/strong\u003e individual ingredient amounts are provided rather than hidden in a proprietary blend.\u003c\/li\u003e\n  \u003c\/ul\u003e\n\n  \u003cp\u003eThe combination is particularly relevant to adults who want to explore longevity-focused nutritional support beyond conventional vitamin and mineral products.\u003c\/p\u003e\n\n  \u003ch2\u003eWho Is It For?\u003c\/h2\u003e\n\n  \u003cp\u003e\u003cstrong\u003enuBioAge 1-MNA + Apigenin\u003c\/strong\u003e may be suitable for adults interested in:\u003c\/p\u003e\n\n  \u003cul\u003e\n    \u003cli\u003eHealthy aging and longevity-focused nutrition\u003c\/li\u003e\n    \u003cli\u003eNormal vascular and endothelial function\u003c\/li\u003e\n    \u003cli\u003eHealthy circulation\u003c\/li\u003e\n    \u003cli\u003eCellular energy metabolism\u003c\/li\u003e\n    \u003cli\u003eNAD+ metabolism and NAD+ preservation research\u003c\/li\u003e\n    \u003cli\u003eCD38-related cellular signaling pathways\u003c\/li\u003e\n    \u003cli\u003eAntioxidant and inflammatory response support\u003c\/li\u003e\n    \u003cli\u003eCombining 1-MNA and apigenin in one supplement\u003c\/li\u003e\n    \u003cli\u003eA vegetarian capsule with clearly specified ingredient quantities\u003c\/li\u003e\n    \u003cli\u003eA convenient once-daily cellular wellness routine\u003c\/li\u003e\n  \u003c\/ul\u003e\n\n  \u003ch2\u003eSuggested Use\u003c\/h2\u003e\n\n  \u003cp\u003e\u003cstrong\u003eAdults:\u003c\/strong\u003e Take \u003cstrong\u003e1 capsule daily\u003c\/strong\u003e, or as directed by a healthcare professional.\u003c\/p\u003e\n\n  \u003cp\u003eEach capsule provides:\u003c\/p\u003e\n\n  \u003cul\u003e\n    \u003cli\u003e\n\u003cstrong\u003e1-MNA:\u003c\/strong\u003e 250 mg\u003c\/li\u003e\n    \u003cli\u003e\n\u003cstrong\u003eApigenin (98%):\u003c\/strong\u003e 150 mg\u003c\/li\u003e\n  \u003c\/ul\u003e\n\n  \u003cp\u003eOne bottle contains 30 capsules, providing a 30-day supply at the recommended daily intake.\u003c\/p\u003e\n\n  \u003ch2\u003eCaution\u003c\/h2\u003e\n\n  \u003cp\u003eConsult a healthcare professional before use if you are pregnant, breastfeeding, taking prescription medications, or have a medical condition.\u003c\/p\u003e\n\n  \u003cp\u003eIndividuals taking medications that affect blood pressure, circulation, or blood clotting should discuss the use of this supplement with their healthcare provider.\u003c\/p\u003e\n\n  \u003cp\u003eDo not exceed the recommended serving without professional guidance. Discontinue use if an adverse reaction occurs.\u003c\/p\u003e\n\n  \u003cp\u003eThis formula is intended for adult use. Keep out of reach of children.\u003c\/p\u003e\n\n  \u003ch2\u003eProduct Specifications\u003c\/h2\u003e\n\n  \u003ctable\u003e\n    \u003cthead\u003e\n      \u003ctr\u003e\n        \u003cth\u003eSpecification\u003c\/th\u003e\n        \u003cth\u003eDetails\u003c\/th\u003e\n      \u003c\/tr\u003e\n    \u003c\/thead\u003e\n    \u003ctbody\u003e\n      \u003ctr\u003e\n        \u003ctd\u003eBrand\u003c\/td\u003e\n        \u003ctd\u003enuBioAge\u003c\/td\u003e\n      \u003c\/tr\u003e\n      \u003ctr\u003e\n        \u003ctd\u003eProduct Name\u003c\/td\u003e\n        \u003ctd\u003e1-MNA + Apigenin\u003c\/td\u003e\n      \u003c\/tr\u003e\n      \u003ctr\u003e\n        \u003ctd\u003eProduct Type\u003c\/td\u003e\n        \u003ctd\u003eDietary Supplement\u003c\/td\u003e\n      \u003c\/tr\u003e\n      \u003ctr\u003e\n        \u003ctd\u003ePrimary Focus\u003c\/td\u003e\n        \u003ctd\u003eVascular Support + NAD+ Preservation\u003c\/td\u003e\n      \u003c\/tr\u003e\n      \u003ctr\u003e\n        \u003ctd\u003eActive Ingredients\u003c\/td\u003e\n        \u003ctd\u003e1-MNA and Apigenin\u003c\/td\u003e\n      \u003c\/tr\u003e\n      \u003ctr\u003e\n        \u003ctd\u003e1-MNA per Capsule\u003c\/td\u003e\n        \u003ctd\u003e250 mg\u003c\/td\u003e\n      \u003c\/tr\u003e\n      \u003ctr\u003e\n        \u003ctd\u003eApigenin per Capsule\u003c\/td\u003e\n        \u003ctd\u003e150 mg (98%)\u003c\/td\u003e\n      \u003c\/tr\u003e\n      \u003ctr\u003e\n        \u003ctd\u003eServing Size\u003c\/td\u003e\n        \u003ctd\u003e1 Capsule\u003c\/td\u003e\n      \u003c\/tr\u003e\n      \u003ctr\u003e\n        \u003ctd\u003eCapsules per Bottle\u003c\/td\u003e\n        \u003ctd\u003e30\u003c\/td\u003e\n      \u003c\/tr\u003e\n      \u003ctr\u003e\n        \u003ctd\u003eServings per Bottle\u003c\/td\u003e\n        \u003ctd\u003e30\u003c\/td\u003e\n      \u003c\/tr\u003e\n      \u003ctr\u003e\n        \u003ctd\u003eSuggested Use\u003c\/td\u003e\n        \u003ctd\u003e1 Capsule Daily\u003c\/td\u003e\n      \u003c\/tr\u003e\n      \u003ctr\u003e\n        \u003ctd\u003eCapsule Type\u003c\/td\u003e\n        \u003ctd\u003eVegetarian Hypromellose Capsule\u003c\/td\u003e\n      \u003c\/tr\u003e\n      \u003ctr\u003e\n        \u003ctd\u003eDistributor\u003c\/td\u003e\n        \u003ctd\u003enuBioAge, West Palm Beach, Florida, USA\u003c\/td\u003e\n      \u003c\/tr\u003e\n    \u003c\/tbody\u003e\n  \u003c\/table\u003e\n\n  \u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\n  \u003ch3\u003eWhat is nuBioAge 1-MNA + Apigenin?\u003c\/h3\u003e\n  \u003cp\u003eIt is a dual-ingredient dietary supplement containing 250 mg of 1-methylnicotinamide and 150 mg of apigenin per capsule, formulated for vascular support, NAD+ metabolism, and healthy aging.\u003c\/p\u003e\n\n  \u003ch3\u003eHow much 1-MNA is in each capsule?\u003c\/h3\u003e\n  \u003cp\u003eEach capsule contains 250 mg of 1-MNA as 1-methylnicotinamide chloride.\u003c\/p\u003e\n\n  \u003ch3\u003eHow much apigenin is in each capsule?\u003c\/h3\u003e\n  \u003cp\u003eEach capsule contains 150 mg of apigenin standardized to 98%.\u003c\/p\u003e\n\n  \u003ch3\u003eWhat is 1-MNA?\u003c\/h3\u003e\n  \u003cp\u003e1-MNA, or 1-methylnicotinamide, is a naturally occurring metabolite formed during nicotinamide metabolism. It has been investigated for its involvement in vascular function and cellular signaling.\u003c\/p\u003e\n\n  \u003ch3\u003eIs 1-MNA the same as NMN?\u003c\/h3\u003e\n  \u003cp\u003eNo. 1-MNA and NMN are different compounds. NMN is an NAD+ precursor, while 1-MNA is a methylated metabolite of nicotinamide.\u003c\/p\u003e\n\n  \u003ch3\u003eDoes 1-MNA directly increase NAD+?\u003c\/h3\u003e\n  \u003cp\u003e1-MNA is not a conventional NAD+ precursor like NMN or nicotinamide riboside. Its biological effects are investigated primarily in relation to nicotinamide metabolism, vascular function, and cellular signaling.\u003c\/p\u003e\n\n  \u003ch3\u003eWhat is apigenin?\u003c\/h3\u003e\n  \u003cp\u003eApigenin is a naturally occurring plant flavonoid found in foods and herbs such as parsley, chamomile, and celery. It is studied for its antioxidant-related properties and cellular signaling activity.\u003c\/p\u003e\n\n  \u003ch3\u003eWhat is CD38?\u003c\/h3\u003e\n  \u003cp\u003eCD38 is an enzyme involved in NAD+ metabolism and cellular signaling. It is one of the enzymes that consume NAD+ in the body.\u003c\/p\u003e\n\n  \u003ch3\u003eDoes apigenin inhibit CD38?\u003c\/h3\u003e\n  \u003cp\u003eLaboratory research has identified apigenin as a CD38 inhibitor under certain experimental conditions. Whether oral supplementation at the amount in this product significantly inhibits CD38 in humans remains to be established.\u003c\/p\u003e\n\n  \u003ch3\u003eWhat does NAD+ preservation mean?\u003c\/h3\u003e\n  \u003cp\u003eNAD+ preservation refers to supporting the balance between NAD+ production and consumption. The manufacturer associates apigenin with this concept because of its investigated effects on CD38 activity.\u003c\/p\u003e\n\n  \u003ch3\u003eDoes this product contain NMN or NR?\u003c\/h3\u003e\n  \u003cp\u003eNo. The two labeled active ingredients are 1-MNA and apigenin. The formula does not list NMN or nicotinamide riboside.\u003c\/p\u003e\n\n  \u003ch3\u003eCan this supplement support circulation?\u003c\/h3\u003e\n  \u003cp\u003eThe manufacturer positions 1-MNA as an ingredient for healthy vascular function and circulation. Research into its biological activity is ongoing, and the supplement is not intended to treat circulatory disorders.\u003c\/p\u003e\n\n  \u003ch3\u003eDoes this formula support healthy aging?\u003c\/h3\u003e\n  \u003cp\u003eThe formula is designed around biological pathways relevant to vascular wellness and NAD+ metabolism. However, it has not been established that this combination extends human lifespan or prevents age-related disease.\u003c\/p\u003e\n\n  \u003ch3\u003eDoes 1-MNA + Apigenin provide immediate energy?\u003c\/h3\u003e\n  \u003cp\u003eThe ingredients are associated with metabolic and cellular signaling pathways rather than immediate stimulation. This is not a caffeine-based energy supplement.\u003c\/p\u003e\n\n  \u003ch3\u003eIs this product suitable for vegetarians?\u003c\/h3\u003e\n  \u003cp\u003eThe supplement uses a vegetable capsule made from hypromellose. The supplied label does not identify any animal-derived ingredients.\u003c\/p\u003e\n\n  \u003ch3\u003eHow many capsules are in one bottle?\u003c\/h3\u003e\n  \u003cp\u003eEach bottle contains 30 capsules.\u003c\/p\u003e\n\n  \u003ch3\u003eHow many servings are in one bottle?\u003c\/h3\u003e\n  \u003cp\u003eEach bottle provides 30 servings.\u003c\/p\u003e\n\n  \u003ch3\u003eHow long does one bottle last?\u003c\/h3\u003e\n  \u003cp\u003eAt the recommended intake of one capsule daily, a bottle lasts 30 days.\u003c\/p\u003e\n\n  \u003ch3\u003eHow should I take 1-MNA + Apigenin?\u003c\/h3\u003e\n  \u003cp\u003eThe manufacturer's suggested use is one capsule daily.\u003c\/p\u003e\n\n  \u003ch3\u003eCan I combine this product with NAD+ supplements?\u003c\/h3\u003e\n  \u003cp\u003eThe formula contains ingredients related to NAD+ metabolism, but evidence establishing the safety or added benefits of combining it with NMN, NR, or other NAD+-focused supplements is limited. Consult a healthcare professional before combining them.\u003c\/p\u003e\n\n  \u003ch3\u003eIs apigenin the same as chamomile extract?\u003c\/h3\u003e\n  \u003cp\u003eNo. Apigenin is a specific flavonoid that occurs naturally in chamomile and other plants. A standardized apigenin supplement provides a defined quantity of the compound, unlike a general chamomile extract.\u003c\/p\u003e\n\n  \u003ch3\u003eAre 1-MNA and apigenin equally dosed?\u003c\/h3\u003e\n  \u003cp\u003eNo. Each capsule contains 250 mg of 1-MNA and 150 mg of apigenin.\u003c\/p\u003e\n\n  \u003ch3\u003eDoes the formula contain a proprietary blend?\u003c\/h3\u003e\n  \u003cp\u003eNo. Both active ingredient quantities are individually disclosed on the Supplement Facts label.\u003c\/p\u003e\n\n  \u003ch3\u003eWhat are the other ingredients?\u003c\/h3\u003e\n  \u003cp\u003eThe other ingredients are hypromellose (vegetable capsule), microcrystalline cellulose, magnesium stearate, and silicon dioxide.\u003c\/p\u003e\n\n  \u003ch3\u003eIs the supplement intended for children?\u003c\/h3\u003e\n  \u003cp\u003eThe product is presented as an adult wellness supplement. Use in children should only occur under the direction of an appropriately qualified healthcare professional.\u003c\/p\u003e\n\n  \u003ch3\u003eWho should consult a healthcare professional before use?\u003c\/h3\u003e\n  \u003cp\u003ePregnant or breastfeeding individuals, people with medical conditions, and those taking prescription medications should consult a healthcare professional before using this supplement.\u003c\/p\u003e\n\n  \u003ch2\u003eStorage\u003c\/h2\u003e\n\n  \u003cp\u003eStore in a cool, dry place away from excessive heat, humidity, and direct sunlight. Keep the bottle tightly closed and out of reach of children. Do not use if the safety seal is damaged or missing.\u003c\/p\u003e\n\n  \u003cp\u003e\u003csmall\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This product is intended for nutritional support and is not intended to diagnose, treat, cure, or prevent any disease. Information about individual ingredients and their biological pathways does not establish clinical efficacy for the finished combination.\u003c\/small\u003e\u003c\/p\u003e\n\u003c\/section\u003e","brand":"nuBioAge","offers":[{"title":"Default Title","offer_id":67987124650173,"sku":"50019","price":62.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0614\/6356\/0381\/files\/New-1-MNAApigenin-photo-2.png?v=1793037297","url":"https:\/\/nutrigeek.shop\/ru\/products\/1-mna-apigenin-30-capsules-nubioage","provider":"Nutrigeek","version":"1.0","type":"link"}