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Total Gut Restoration Kit 1 (Capsules) Microbiome Labs

In stock
SKU: 95784
Regular price $355.99 USD

Total Gut Restoration is an advanced 3-month protocol to support and restore gut health. A triple-threat of three unique supplements works to support a healthy gut, including maintaining a healthy and harmonious microbial ecosystem, promoting a protective gut barrier, and supplying precision bacterial species that support balanced immune and digestive function. Indeed, a healthy gut is a necessary foundation for supporting a healthy immune system.

Total Gut Restoration Studies


Study Details and Results


Total Gut Restoration

in vitro (M-SHIME®)

Fecal samples were used in vitro to evaluate the effects on the gut microbiome using the Total Gut Restoration supplementation system. TGR supplementation resulted in short-chain fatty acids (SCFAs) production and supported intestinal barrier function and immune function.

DOI: 10.2217

MegaSporeBiotic™ and MegaMucosa™

The combination of MegaSpore™ and MegaMucosa™ promoted immune function and provided support to colonic mucosa.

DOI: 10.3390


10 days

300 million CFU of MegaSporeBiotic™ supplementation supported immune function and iron levels in mice.

DOI: 10.1002


12 weeks

12 weeks of supplementation with MegaSporeBiotic™ supported triglyceride levels in study subjects.

PMID: 33041703


Administration of MegaSporeBiotic™ was shown to support liver function.

DOI: 10.3390


Study Details and Results



60 days

MegaSporeBiotic™ provided relief for occasional abdominal discomfort and supported elimination and digestive health in study subjects.

DOI: 10.3390


30 days

MegaSporeBiotic™ demonstrated cardiac-supportive and immune-supportive properties.

DOI: 10.4291

MegaSporeBiotic™ and MegaPre™

MegaSporeBiotic™ and MegaPre™ promoted microbial diversity in the transverse and descending colon. Additionally, this synbiotic combination promoted the production of all SCFAs in the gut, including acetate, propionate, and butyrate.

DOI: 10.1016


3 weeks

MegaSporeBiotic promoted bacterial diversity and supported ammonia, propionate, and lactate levels.

DOI: 10.1016

MegaSporeBiotic™ and antibiotics

MegaSporeBiotic™ was shown to support immune system health and help maintain normal intestinal flora.


Kit 1 Includes One MegaSporeBiotic 180 Capsules

MegaSporeBiotic™ is a 100% spore-based, broad-spectrum probiotic shown to maintain healthy gut barrier function. This unique all-spore formula effectively RECONDITIONS the gut by promoting microbial diversity and maintaining key health-promoting, commensal gut bacteria. MegaSporeBiotic™ boasts a 5-year shelf-life, does not require refrigeration, and maintains a healthy gut microbiome.


Kit 1 Includes Two MegaPre 180 Capsules

MegaPre™ is the first Precision Prebiotic™ supplement made up of clinically tested, non-digestible oligosaccharides that can increase microbial diversity and selectively feed beneficial bacteria like Akkermansia muciniphilaFaecalibacterium prausnitzii, and Bifidobacteria. MegaPre™ REINFORCES the beneficial microbial changes created by MegaSporeBiotic™ to promote a strong and diverse microbiome.


Kit 1 Includes One MegaMucosa 180 Capsules

MegaMucosa is the first complete mucosal support supplement of its kind, formulated to support a healthy mucosal barrier. MegaMucosa also contains dairy-free immunoglobulins clinically shown to support a healthy immune system in the mucosa and a state-of-the-art flavobiotic shown to support microbial diversity and short-chain fatty acid production.



Week 1: Take 1 capsule every other day

Week 2: Take 1 capsule daily

Week 3-4+: Take 2 capsules daily


Take with a meal


MegaPre Capsules

In addition to MegaSporeBiotic

Week 5: Take 3 capsules daily

Week 6-8+: Take 6 capsules daily


Take with or without a meal


MegaMucosa Capsules

In addition to MegaSporeBiotic and MegaPre

Week 9: Take 3 capsules daily

Week 10-12+: Take 6 capsules daily


Take with or without a meal