nuBioAge

GUTTIDES™ by nuBioAge — BPC-157 + KPV Blend (30 Capsules)

GUTTIDES from nuBioAge is a once-daily capsule combining two well-known bioactive compounds — BPC-157 (Body Protection Compound, as arginate salt) and the KPV tripeptide (Lysine-Proline-Valine). Each capsule delivers 500 mcg of each, making GUTTIDES a simple, convenient addition to a daily gut-wellness routine.

What's inside

• Body Protective Compound (as BPC-157 Arginate Salt): 500 mcg
• KPV Peptide (Lysine-Proline-Valine): 500 mcg
• Other ingredients: Vegetable Capsule (Hypromellose), Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide

Suggested use: Take one capsule daily, or as directed by your healthcare provider.

Why buy GUTTIDES at Nutrigeek Nutrigeek carries the full nuBioAge line as an authorized retailer. Every order is sourced through authorized channels, so you receive an authentic, properly stored product. Enjoy fast US shipping, free shipping on orders over $50, and a 30-day return policy. GUTTIDES is one of our most-reviewed nuBioAge products — see verified customer feedback below.

Questions about GUTTIDES or how it fits with other nuBioAge formulas? Email us at m@nutrigeek.shop.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

As an alternative to statins, it leverages the synergy of leucine and nicotinic acid with polymethoxylated flavones and tocotrienols to improve lipid biomarkers, fat oxidation, and circadian rhythms. SIRT genes are targeted due to their signaling to regulate fat oxidation, mitochondrial function, inflammatory cytokines, and antioxidant pathways. SIRT genes depend on NAD+ levels to be activated through AMPK’s nutrient-sensing capabilities. This axis between SIRT1/NAD+/AMPK is the focus of Sytrinol® LNA and its ability to improve metabolism and dyslipidemia.

Ingredients

DIHEXA, a synthetic peptide designed to significantly enhance cognitive functions. Specifically formulated to cross the blood-brain barrier, promoting the growth of new neurons and synapses, which are crucial for cognitive enhancement.

Mechanism of Action

Dihexa functions by increasing the levels of brain-derived neurotrophic factor (BDNF), a key protein involved in the growth, maintenance, and survival of neurons. The peptide facilitates the formation of new synapses and enhances the plasticity of existing neuronal connections, which are essential processes for learning and memory. It also helps facilitate new blood vessel growth in the brain.

Healthcare providers may be interested in Dihexa for several reasons including: 

Enhanced Focus and Cognitive Clarity: The peptide's ability to significantly increase BDNF levels plays a central role here, as BDNF is essential for supporting the survival and growth of neurons, and for facilitating synaptic plasticity, which is the brain's ability to adapt to new information

Memory Improvement: Memory enhancement through Dihexa is linked to its potent neurogenic effects, which are several orders of magnitude stronger than BDNF alone. By binding to and activating HGF, this promotes the formation of dendritic spines, which are crucial for memory storage and retrieval. This action not only helps in forming new memory pathways but also strengthens existing ones, thereby improving both short-term and long-term memory capabilities

Reduction of Brain Fog: The reduction of brain fog by Dihexa can be attributed to its overall enhancement of synaptic connectivity and neuroplasticity. Improved synaptic efficiency leads to clearer cognitive processing, allowing for quicker thinking and problem-solving, which directly combats the symptoms of brain fog. Additionally, the upregulation of BDNF and HGF contributes to a healthier neuronal environment, further clearing cognitive obscurities

Recovery Aid for Neurological Health: Dihexa's role in aiding recovery from neurological injuries such as strokes is particularly notable. It accelerates the process of neurogenesis and angiogenesis, which are critical for repairing brain damage and restoring function after a stroke. The peptide's ability to enhance HGF activity is key here, as HGF is known for its regenerative properties in neural tissues

Neuroinflammation Reduction: The reduction of neuroinflammation by Dihexa is another crucial therapeutic aspect. Neuroinflammation is a common underlying factor in many neurodegenerative diseases and cognitive disorders. Dihexa's modulation of HGF and BDNF not only supports neural growth and repair but also provides neuroprotective effects that reduce inflammation and the associated neurotoxicity.

UPPLEMENT FACTS

Serving Size: 1 Capsule
Servings per container: 30

† Daily Value not established

Other Ingredients: Vegetable Capsule (Hypromellose), Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide.

Overview

iCell Water™ is an advanced cellular hydration and performance formula designed to optimize cell signaling and volume through osmolyte balance. By combining neutral amino acid osmolytes and creatine, it supports intracellular hydration, muscle preservation, and cellular efficiency. It’s particularly beneficial for individuals on GLP-1 therapy or those seeking improved recovery, muscle maintenance, and overall vitality.

Key Benefits

• Promotes optimal cellular hydration and osmotic balance
• Helps preserve muscle tissue and prevent muscle loss
• Enhances strength, endurance, and recovery
• Improves cell signaling and protein metabolism
• Supports energy and cardiovascular performance

How It Works

iCell Water™ modulates cellular volume to enhance energy production and hydration efficiency. Its neutral amino acid osmolytes and creatine act on sodium and chloride-dependent transport systems to increase intracellular water and maintain cell structure.

Cellular Pathways

• Creatine acts as an osmolyte via the CT1 transporter, increasing cell water and ATP production.
• Glutamine promotes hepatocyte swelling through sodium-dependent uptake, activating regulatory volume decrease (RVD) mechanisms.
• Alanine, Leucine, and Glycine enhance osmotic pressure and cell expansion through Na⁺/K⁺/Cl⁻ channels.

Why It Matters

Muscle function is a key marker of longevity and reduced mortality risk. Intracellular hydration directly affects muscle performance, protein synthesis, and recovery. Studies show that higher intracellular water levels improve strength, endurance, and overall performance, while dehydration leads to decreased power and muscle efficiency.

Research Highlights

• Higher intracellular water correlates with better muscle strength and reduced fatigue.
• Intracellular water is a major predictor of athletic performance.
• Loss of intracellular water impairs power and grip strength.

Synergy with GLP-1 and Sermorelin

GLP-1 + iCell™

GLP-1 therapy may reduce thirst and cellular hydration, indirectly leading to muscle loss. iCell Water™ helps maintain hydration and muscle cell volume, preventing catabolism and supporting lean tissue during GLP-1 use.

Sermorelin + iCell™

Sermorelin enhances protein synthesis, while iCell™ inhibits protein degradation by expanding cell volume. Together, they synergistically improve muscle repair, strength, and endurance for optimal recovery.

Supplement Facts

† Daily Value not established.

Other Ingredients: Silicon Dioxide

Suggested Use

Mix 2 scoops in 64 ounces of water. Consume daily for best results.

Product Facts

• Per Bottle: 20 servings
• Serving Size: 2 scoops (23.68 g)
• Directions: Take two scoops daily, mixed with 64 oz of water
• Form: Powder
• Flavor: Unflavored

Caution

Consult your physician before use if you are pregnant, nursing, taking medication, or have a medical condition. Keep out of reach of children.

Highlights

• Supports muscle, joint, and cellular hydration
• Enhances performance and endurance
• Works synergistically with GLP-1 and Sermorelin
• Free from artificial sweeteners and additives

Regenatides™ is a groundbreaking oral supplement designed to harness the synergistic power of bioactive peptides and cutting-edge absorption technology. Each capsule delivers 500mcg of TB4-Fragment, 500mcg of BPC-157 (as arginate salt), and 3mg of SNAC, formulated to optimize cellular repair, reduce inflammation, and accelerate recovery.

Per Bottle: 30 capsules

Serving Size: 1

Directions: Take 1 capsule daily

1-MNA, a novel myokine, is a game-changer in cellular health by blocking the enzyme NNMT and optimizing NAD levels in the cells. 1-MNA offers a comprehensive approach to cellular health. Its anti-inflammatory, anti-thrombotic properties and positive effect on vascular endothelium and skeletal muscle energy metabolism make it a promising supplement in the medical field.

Optimized NAD Levels: 1-MNA works to restore and optimize NAD levels in cells, a crucial component for cellular health and energy production.

Anti-inflammatory and Anti-thrombotic Properties: 1-MNA possesses anti-inflammatory and anti-thrombotic characteristics, contributing to improved vascular health.

Inhibition of NNMT: 1-MNA has been shown to inhibit the enzyme NNMT, which when present in high levels, is associated with various diseases. By inhibiting this enzyme, 1-MNA can contribute to overall cellular health and disease prevention.

Benefits

BPC-157, a peptide that is renowned for its healing properties, particularly in accelerating the repair of tendons, muscles, nerves, and ligaments. It exhibits anti-inflammatory effects that help reduce swelling and pain, aiding in quicker and more comfortable recovery. 

Additionally, its potential neuroprotective and 
gut health benefits contribute indirectly to 
overall well-being and recovery processes. 

Cellular Pathways
BPC-157

•    increases fibroblast migration and dispersal
•    induces F-actin formation in fibroblasts
•    enhances vascular expression of VEGFR2.
•    NO pathway and FAK pathway for vascular response due to injury

Why this matters: 

When injuries occur or repair is needed, decreasing inflammation and formation of new blood vessels is required to help the tissue heal. BPC-157 is multi-faceted in helping healing tissues and decreasing recovery times. 

Clinical Studies

The promoting effect of pentadecapeptide 
BPC-157 on tendon healing involves 
tendon outgrowth, cell survival, and cell 
migration.

The activation of migration and spreading can be strengthened by the observation of increased F-actin formation in tendon fibroblasts after BPC-157 treatment. BPC-157 was further proven in the present study to be capable of activating the phosphorylation levels of FAK and paxillin in tendon fibroblasts.

Synergy with GLP-1, Sermorelin:

BPC-157 + PPS for inflammation and pain

BPC-157 exerts anti-inflammatory effects by suppressing pro-inflammatory cytokines and promoting tissue repair, while PPS modulates glycosaminoglycan synthesis and stabilizes the extracellular matrix. Together, they enhance tissue regeneration, inhibit inflammatory signaling pathways, and modulate pain transmission, offering a comprehensive approach to alleviate inflammation and pain.

BPC-157 + Sermorelin for Injury recovery and prevention

Sermorelin’s optimization of growth hormone secretion facilitates tissue repair, while BPC-157’s enhancement of growth hormone receptor density synergistically complements this effect, potentially improving tissue healing and regeneration.