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Metabolic Health
Product Overview
Berberine could be a powerful ally for those looking to manage their blood sugar levels, as it may help lower blood sugar. It also acts as a GLP-1 agonist, which could support weight management. Additionally, berberine is known for its antibacterial properties, heart health benefits, and anti-inflammatory effects.
Our capsules contain plant-derived berberine, provided as berberine hydrochloride, a well-researched and effective form of this key plant compound.
Benefits
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May help regulate glucose levels
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Supports lipid metabolism
Who Can Benefit
-
Individuals looking to maintain healthy blood sugar levels†
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People aiming for weight loss
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Those with high cholesterol
Key Features
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Hypoallergenic Formula: Safe for individuals with sensitive systems or allergies.
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Plant-Based Extract: A natural, low-risk option for supporting overall health.
Storage
Store in a cool, dry place (59°-85°F), away from direct light.
Detailed Overview
Berberine has the potential to support healthy blood sugar levels. Beyond that, it also possesses antibacterial properties and may improve heart health by promoting heart rhythm regularity.
Our Berberine capsules feature plant-derived berberine in the form of berberine hydrochloride, a highly studied and effective form of this powerful compound.
FAQs
What are the potential health benefits of taking Berberine?
Berberine is known for its potential to help manage blood sugar levels, support heart health, assist in weight management, and offer antibacterial benefits, which may enhance immunity during infections.
How does Berberine help with managing blood sugar levels?
Berberine can improve glucose metabolism, which makes it a helpful supplement for managing blood sugar. It has also been shown to stimulate GLP-1 production, supporting blood sugar regulation through multiple mechanisms.
Can Berberine support my weight loss efforts?
Yes, Berberine may aid in weight loss by improving fat metabolism, reducing appetite, and stimulating GLP-1 receptors. It may also slow the growth of fat tissue by promoting enzymes that increase the uptake of glucose and fatty acids.
Suggested Use:
Adults: 2 capsules, 1 to 2 times daily or as directed by a healthcare professional.
Children: As directed by a healthcare professional.
Allergy Statement:
This product is made without common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat/gluten, soybeans, and sesame.
It does not contain synthetic colors, flavors, or preservatives.
Non-GMO.
Vegan.
Caution:
Berberine should not replace any medication.
Consult your physician if you have a medical condition, are taking prescription drugs, or are under 18 years old.
Consult your physician if you are pregnant or nursing before taking this product.
Keep out of reach of children.
Supplement Facts
Serving Size: 2 Capsules
| Amount Per 2 Capsules | mg | % Daily Value |
|---|---|---|
| Berberine (as berberine HCI) (from Amur cork tree) | ||
| (Phellodendron amurense) (bark) | 500 mg | * |
Daily value not established
Other Ingredients:
Microcrystalline cellulose, vegetarian capsule (hydroxypropyl methylcellulose, water), stearic acid, and silicon dioxide.
Метаболическое здоровье
Преимущества и особенности
Натуральный растительный экстракт, клинически доказано поддерживающий здоровый уровень сахара в крови и метаболизм липидов.
Описание
Исследования показывают благоприятную роль берберина в здоровой регуляции глюкозы. Растительный берберин представлен в форме гидрохлорида берберина — наиболее изученной формы.
СВЕДЕНИЯ О ДОБАВКЕ
| Размер порции: 2 капсулы | ||
| Количество на 2 капсулы | % от суточной нормы | |
|---|---|---|
| Берберин (в виде HCI берберина) (из бархата амурского) (Phellodendron amurense) (кора) | 500 mg | * |
| * Суточная норма не установлена | ||
Другие ингредиенты:
Микрокристаллическая целлюлоза, вегетарианская капсула (гидроксипропилметилцеллюлоза, вода), стеариновая кислота и диоксид кремния.
Рекомендуемое применение
Взрослым: 2 капсулы 1–2 раза в день или по назначению специалиста здравоохранения. Детям: по назначению специалиста здравоохранения.
Заявление об аллергенах
Изготовлено без следующих распространенных аллергенов: молоко/казеин, яйца, рыба, моллюски, древесные орехи, арахис, пшеница, глютен, соя и кунжут. Без искусственных красителей, ароматизаторов и консервантов. Веганский продукт и без ГМО.
Предупреждение
Проконсультируйтесь с врачом, если вы беременны, кормите грудью, имеете заболевание или принимаете рецептурные препараты, а также если вам меньше 18 лет. ХРАНИТЬ В НЕДОСТУПНОМ ДЛЯ ДЕТЕЙ МЕСТЕ.
Overview
Berberine 500 mg 90 capsules is a high-potency botanical formula designed to support healthy glucose metabolism, lipid balance, metabolic function, and gut microbiome health. Each capsule provides 500 mg of berberine HCl standardized to 97%, sourced from Indian barberry root (Berberis aristata), delivering a concentrated and practitioner-grade form of this well-studied plant compound.
Berberine is widely used in metabolic support supplements because of its role in supporting healthy blood sugar balance already within normal limits, lipid metabolism, and cellular energy regulation. This formula is ideal for those looking for a berberine HCl 500 mg supplement with clinically relevant potency and clean capsule delivery.
Key Benefits
- Provides 500 mg of berberine HCl (97%) per capsule
- Supports healthy blood glucose metabolism already within normal limits
- Promotes healthy cholesterol and triglyceride balance
- Supports AMPK activity and cellular energy regulation
- Helps support gut microbiome balance and digestive health
- Botanical metabolic support in a concentrated practitioner-style formula
- Well suited for cardiometabolic wellness routines
Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 90
| Ingredient | Amount Per Serving | % Daily Value |
|---|---|---|
| Berberine HCl 97% (from Indian Barberry) (root) (Berberis aristata) | 500 mg | Daily Value not established |
Other Ingredients: Hydroxypropyl methylcellulose, microcrystalline cellulose, rice hull concentrate, gum arabic, sunflower oil, silicon dioxide.
Ingredient Breakdown
| Ingredient | Role in the Formula |
|---|---|
| Berberine HCl 97% | Concentrated plant alkaloid used to support glucose metabolism, lipid balance, and metabolic regulation |
| Indian Barberry Root | Botanical source of berberine used in standardized metabolic support formulas |
How It Works
Berberine is a plant-derived alkaloid best known for its role in supporting glucose metabolism, lipid balance, and cellular energy pathways. One of its key mechanisms is its interaction with AMP-activated protein kinase (AMPK), an enzyme involved in regulating energy use, fat metabolism, and glucose handling at the cellular level. This is one reason berberine is frequently included in formulas aimed at metabolic balance and cardiometabolic support.
In addition to metabolic support, berberine is also relevant for gut microbiome health. Its interaction with the intestinal environment makes it useful in broader wellness strategies where digestion, microbial balance, and metabolic health overlap. This gives the formula a wider benefit profile than a simple blood sugar support product alone.
Because this formula delivers 500 mg of berberine HCl standardized to 97% per capsule, it aligns well with the strength commonly used in berberine-focused supplementation routines. For people looking for a high-strength berberine supplement for glucose support, lipid balance, and gut health, this is a strong single-ingredient option.
Suggested Use
As a dietary supplement, take 1 capsule three times daily, or as directed by a healthcare practitioner.
FAQ
What does Berberine 500 mg support?
It is designed to support healthy glucose metabolism, lipid balance, metabolic function, and gut microbiome health.
How much berberine is in each capsule?
Each capsule provides 500 mg of berberine HCl standardized to 97%.
What is the source of berberine in this formula?
The berberine is derived from Indian barberry root (Berberis aristata).
Why is berberine often used for metabolic support?
Berberine is commonly used because it supports pathways related to glucose handling, lipid metabolism, and AMPK activity, which are central to metabolic balance.
Who may consider this product?
It may be useful for individuals focused on cardiometabolic wellness, healthy blood sugar support already within normal limits, lipid balance, and gut-microbiome-related wellness strategies.
Storage
Store in a cool, dry place, tightly capped, away from light. Keep out of the reach of children. Use only if safety seal is intact. Variations in product color may occur.
METABOLIC SUPPORT
WHAT IT DOES
Berberine offers metabolic support for glucose and lipid metabolism.* It also supports healthy blood sugar and insulin levels already within a normal range.*
HOW IT WORKS
Clinical studies demonstrate that berberine supports healthy lipid metabolism and cholesterol homeostasis.*1-6 Berberine can activate an important metabolic enzyme known as adenosine monophosphate-activated protein kinase (AMPK), a central regulator of cellular energy homeostasis.* Mechanistic research in vitro and in vivo suggests that berberine can decrease cholesterol and triglyceride synthesis by activating AMPK.7-9
In addition to supporting lipid metabolism, berberine supports healthy glucose metabolism and blood sugar management already within a normal range.*2-5 Mechanistic research in vitro suggests that berberine can support healthy glucose regulation through promoting glucose uptake in cells via GLUT4 translocation.7
REFERENCES
- Kong W et al. Nat Med. 2004;10(12):1344-51.
- Yin J et al. Metabolism. 2008;57(5):712-7.
- Zhang Y et al. J Clin Endocrinol Metab. 2008;93(7):2559-2565.
- Yang J et al. Evid Based Complement Alternat Med. 2012;2012:363845.
- Perez-Rubio K et al. Metab Syndr Relat Disord. 2013;11(5):366-9.
- Cao C et al. Exp Ther Med. 2019;17(4):3009-3014.
- Lee YS et al. Diabetes. 2006;55:2256-64.
- Brusq JM et al. J Lipid Res. 2006;47(6):1281-8.
- Jiang D et al. Lipids Health Dis. 2016;15:214.
DIRECTIONS
Berberine Directions and/or Dosage Adults take 1 capsule two to three times daily, or as recommended by a healthcare professional.
Warning Do not use if you are pregnant or nursing. If you have diabetes, or are taking any prescription drugs, consult a healthcare professional before use. Keep out of reach of children. Safety sealed with inner seal. Do not use if seal is broken or missing. Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.
| Nutritional Information: Food supplement | ||
| Serving Size: 1 | ||
| Servings Per Container: 60/120 | ||
| Amount Per Serving | %Daily Value* | |
| Berberine HCl | 500 mg | † |
| † Daily Value not established. | ||
Ingredients
plant-derived capsule (hypromellose), cellulose, calcium laurate, silica
FAQS
Q: Are there side effects associated with this product?
A: Side effects have been limited to transient gastrointestinal discomfort.
Berberine is a plant-based alkaloid long valued in traditional wellness practices — and now supported by modern science. It’s known for its ability to balance blood sugar levels, improve insulin sensitivity, support healthy weight management, and promote cardiovascular health.
Global Healing’s Berberine formula features organic Berberis Aristata extract paired with organic Ceylon cinnamon and black pepper to enhance absorption and effectiveness. This potent blend helps maintain metabolic function, cholesterol balance, and overall wellness.
Suggested Use:
Take 2 capsules daily with or without food, or as recommended by your healthcare provider.
Supplement Facts:
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Serving Size: 2 Capsules
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Servings Per Container: 30
| Ingredient | Amount Per Serving |
|---|---|
| Organic Berberis Aristata Extract | 1200 mg |
| Organic Ceylon Cinnamon | 100 mg |
| Organic Black Pepper | 10 mg |
*Daily Value not established.
Other Ingredients:
Organic vegetable capsule, organic MCT powder, organic rice hulls, ormus supercharged minerals.
Zahler's Berberine provides Berbevis® to help support healthy glucose levels and metabolism.
- Provides a robust dose of Berberine
- Supports healthy metabolism
- Easy-to-swallow capsules
Berberine is naturally extracted from plants and is associated with many benefits. Zahler's Berberine Includes includes Berbevis® and supports healthy blood glucose levels, heart health and metabolism.
Product FAQs
If I have a pea allergy, can I consume this product?
The Zahler Berberine contains Pea Protein Isolate, so if you're allergic to peas you should avoid this product.
Do I need to have a specific reason or condition to take Zahler Berberine or could I just take it for overall wellness support?
As long as you're not pregnant, nursing, on medications or have specific medical conditions you can go ahead and use Zahler Berberine. You don't need a special reason to take it. If you have a medical condition or are taking medications, discuss taking this product (and all nutritional supplements) with your doctor before use.
Suggested use
Take 2 capsules daily, with food, or as directed by your healthcare practitioner.
Warnings
Keep out of reach of children.
Do not use if safety seal is damaged or missing. Do not use if you are pregnant or nursing. This product should not be used by children or by individuals with liver or gallbladder disease. If you're taking medication or have a medical condition, discuss with your healthcare practitioner before using this product.
You may need additional supplements to support a healthy diet; consult your nutritionist for a formula that is right for you.
Store tightly closed in a cool dry place, away from direct sunlight.
| Supplement facts | ||
| Serving Size: 2 Capsules | ||
| Servings Per Container: 30 | ||
| Amount Per Serving | %Daily Value | |
|
Berbevis® Berberine Phospholipids Complex Indian Barberry Root Extract, Pea Protein Isolate, Sunflower Lecithin, Grape Seed Extract, Hydroxypropylcellulose. |
550 mg | * |
| Berberine HCl | 450 mg | * |
| *Daily Value not established. | ||
Other ingredients
Hypromellose (capsule), calcium laurate.
Made in the USA with globally sourced ingredients.
- Metabolism-Supporting Powerhouse: Berberine supports the body's natural metabolic processes and offers numerous benefits for overall health and wellness.*
- Sustainably Sourced: Enzymedica Berberine comes from Barberry (Berberis aristata), with no artificial fillers or excipients, and is standardized to 95%.
- Targeted-Delivery Capsules: Delivers a consistent amount of Berberine with each and every serving for targeted release and absorption.*
- Dosage: Just 1-2 capsules with meals, 3 times a day for metabolic support; take between meals with water; Contains no gluten, milk, casein, soy, egg, artificial colors, flavors, or GMOs*
- Great Health Made Easier: We source the best ingredients, validate them with the latest science and formulate clean, effective products. We invest in people and planet initiatives that support our values and legacy.
Benefits
Nature has a solution for everything, even helping to metabolize blood sugar.*
The alkaloid berberine has long been used for various health benefits. Sustainably sourced from Barberry, Enzymedica’s Berberine 800 mg is for metabolic support.* This metabolism-boosting powerful supports the body’s natural metabolic processes and offers numerous benefits for overall health and wellness.*
Used traditionally for centuries, Berberine is renowned as a safe and effective remedy for supporting blood sugar and cholesterol levels already within a normal range, healthy metabolism and microbiome balance.*
Science
What is Berberine?
Berberine is an alkaloid found in plants like Goldenseal, Barberry, Oregon Grape and Goldthread. Alkaloids help plants protect themselves against predators and regulate their growth. They also offer benefits for the overall health of humans.*
Berberine has a rich history of use in traditional herbalism for a number of common purposes, especially to support blood sugar metabolism and promote healthy weight loss.* Modern research now bolsters what common wisdom told us about berberine.
There are numerous research studies that support Berberine's use as a dietary supplement. In a series of two double-blind studies, Berberine was found to be influential for healthy weight management.*1,2
What makes Enzymedica's Berberine better?
Berberine can be sourced from many plants, including Barberry and Goldenseal. Unfortunately, Goldenseal is an “at risk” plant due to overharvesting in the wild and its use is strongly discouraged by plant conservationists.
The form we use comes from Berberis aristata, commonly called Indian barberry, which grows abundantly, is naturally sustainable and rich in valuable phytochemicals.
Our Berberine is also standardized at 95%. This provides a consistent amount of Berberine with each and every serving. In addition, our capsules are enteric-coated for targeted release. In the GI tract, berberine binds with other berberine molecules to form insoluble compounds that can’t be absorbed. Our formula uses targeted-delivery capsules to eliminate that issue.
References:
1. Yang, J., Yin, J., Gao, H., Xu, L., Wang, Y., and Li, M. Berberine improves insulin sensitivity by inhibiting fat store and adjusting adipokines profile in human preadipocytes and metabolic syndrome patients. Evid. Based Complement. Altern. Med. 2012; 2012: 363845.
2. Perez-Rubio, K.G., Gonzalez-Ortiz, M., Martinez-Abundis, E., Robles-Cervantes, J.A., and Espinel-Bermudez, M.C. Effect of berberine administration on metabolic syndrome, insulin sensitivity, and insulin secretion. Metab. Syndr. Relat. Disord. 2013; 11: 366–369.
Consult with physician prior to use if you are pregnant or nursing, taking medications or have a medical condition.
Caution: This product is not intended for individuals with impaired glucose metabolism such as prediabetes or diabetes.
Berberine may interfere with the absorption of tetracycline and related antibiotics. Berberine produces significant inhibition of CYP3A enzymes in humans. Because these enzymes metabolize most drugs, berberine may decrease the clearance of many medications thereby potentiating their effect.
Suggested Use
-
1-2 capsules with meals, three times a day.
-
Consult with a physician prior to use if you are pregnant, nursing, taking medications or have a medical condition.
Researchers have discovered that your mitochondria – those powerful energy factories within your cells – actually drive your body’s cellular aging.
As you grow older, your mitochondria undergo damage and mutations that affect their function. These damaged mitochondria accumulate in your cells while your cells produce fewer new mitochondria. Having healthy mitochondria is key to living a long, healthy life, so it’s important to give your mitochondria the support they need to stay healthy.
Two nutrients that support mitochondrial health in uniquely powerful ways are Berberine and PQQ (Pyrroloquinoline quinone). Our special synergistic formula, Berberine and MicroPQQ Advanced, provides a two-punch approach to optimizing your mitochondrial and your metabolic health as it helps to:
- Protect your mitochondria from oxidative damage.*
- Promote the growth of new mitochondria.*
- Support neurological and cognitive function.*
- Support immune and cardiovascular health.*
- Encourage fat burning.*
- Promote insulin, leptin and adiponectin function for a healthy metabolism.*
- Support healthy blood sugar levels already in the normal range.*
- Promote healthy insulin sensitivity.*
- Promote the growth of healthy gut microflora.*
- Support healthy lipid metabolism.*
With a patented, long-lasting and highly effective form of PQQ, Berberine and MicroPQQ Advanced offers unique benefits you won’t find in other Berberine or PQQ supplements.
Take action today to support your mitochondrial function, and order Berberine and MicroPQQ Advanced.
Supplement Facts
Suggested Use: Adults, as a dietary supplement, take one (1) capsule daily with a meal.
Caution: Keep out of reach of children. Do not use if safety seal is broken. If you are nursing, pregnant, taking medication, or have a medical condition, consult your physician before taking this product.
- Serving Size: 1 Capsule
- Servings Per Container: 30/90
| Nutrient | Amount Per Serving | % Daily Value |
|---|---|---|
| Berberine HCl (from Amur Cork Tree Bark) | 500 mg | * |
| Pyrroloquinoline Quinone Disodium Salt (PQQ) Complex^ | 10 mg | * |
*Daily Value (DV) not established.
^MicroPQQ® is a registered trademark of BioActives, LLC. Contains 50% PQQ.
Other Ingredients: Capsule (Hydroxypropyl Methylcellulose), Ascorbyl Palmitate, Microcrystalline Cellulose, Silicon Dioxide, Hydroxypropyl Methylcellulose, Carnauba Wax, Beta-Cyclodextrin.
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