Life Extension

• One of the most abundant amino acids in the body
• Called one of the most essential substances in the human body
• Thought to help regulate central nervous system
• Shows cardiovascular and neuroprotective properties
• Promotes system-wide health

• Insulin sensitivity and glucose utilization.6,7
• Proper utilization of minerals including calcium.1
• Healthy eyes.1,8,9
• Central nervous system regulation.2
• Cell membrane stability and water balance (osmoregulation).2,10,11
• Bile salt formation.1,10
• Cognitive function and neuron integrity.2,10,12
• Liver function.13
• Heart health.11,14-16

• KEEP OUT OF REACH OF CHILDREN
• DO NOT EXCEED RECOMMENDED DOSE
• Do not purchase if outer seal is broken or damaged.
• When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Prestigious scientific journals have highlighted gamma tocopherol as one of the most critically important forms of vitamin E for those seeking optimal health benefits. In fact, studies show the combination of alpha- and gamma-tocopherol supplementation appears to be superior to either supplementation alone on biomarkers of oxidative stress and on inflammatory factors.135, 136

Most commercial vitamin E supplements contain little, if any, gamma tocopherol. They instead rely on alpha tocopherol as the primary ingredient. However, it is gamma tocopherol (not the alpha form) that quenches peroxynitrite, the free radical that plays a major role in the development of age-related decline.137

Sesame Lignans: The Natural Vitamin E Booster

Life Extension has uncovered research suggesting that adding sesame lignans to gamma tocopherol may significantly enhance its beneficial effects.138-140 Sesame and its lignans have been shown to boost antioxidative activity in the tissues by elevating the levels of two antioxidative vitamins, vitamin C and E.141

In a human study that combined gamma tocopherol with sesame lignans, gamma tocopherol/sesame was 25% more effective than gamma tocopherol/tocotrienols in inhibiting tissue measurements for free radical and inflammatory response.142 Since tocotrienols are considered nature’s most potent antioxidants, the fact that low-cost gamma tocopherol with sesame is more effective is a remarkable finding.

Life Extension has fortified the popular Gamma E Tocopherol supplement with standardized sesame lignans. Consumers obtain superior benefits at a much lower cost. This formula provides potent doses of gamma tocopherol along with sesame lignan extract to augment the antioxidant effects of gamma tocopherol.

References Available Upon Request

Take one (1) softgel once or twice daily with food, or as recommended by a healthcare practitioner.

Serving Size: 1 softgel

Amount Per Serving
Vitamin E ... 45IU
(as D-alpha tocopherol)
Gamma E mixed tocopherols ... 360mg
Typical profile:
Gamma tocopherol 178 - 244 mg
Delta tocopherol 65 - 98 mg
Alpha tocopherol 27 - 39 mg
Beta tocopherol < 16 mg
Sesame seed lignan extract ... 20mg

Other Ingredients: gelatin, glycerin, sunflower oil, purified water, silica, carob color, rosemary extract.

Non-GMO

Caution
If you are taking anti-coagulant or anti-platelet medications, or have a bleeding disorder, consult your healthcare provider before taking this product.

Warnings

• KEEP OUT OF REACH OF CHILDREN
• DO NOT EXCEED RECOMMENDED DOSE
• Do not purchase if outer seal is broken or damaged.
• When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

How you feel is related to digestive health. Research indicates that bi-directional communication between your digestive tract and your brain plays a major role in mood and emotional health. FLORASSIST® Mood Improve combines innovative probiotics with a standardized saffron extract to support emotional well-being and help maintain a balanced mood.

Believe it or not, digestive health is tied to how you feel. That’s why Life Extension's created their FLORASSIST® Mood Improve formula.

FLORASSIST® Mood Improve Benefits

• Promotes balanced mood and brain health with saffron and probiotics
• Supports healthy signaling between your digestive tract & brain
• Encourages a healthy mental outlook & supports emotional well-being
• Helps relieve minor digestive discomfort that can accompany everyday stress

Suggested Use:

Take one (1) capsule daily, or as recommended by a healthcare practitioner.

Serving Size: 1 Vegetarian Capsules

Amount Per Serving

Mood Probiotic Blend … 357mg

(3 Billion CFU†)

Lactobacillus helveticus Rosell-52 ME^

Bifidobacterium longum Rosell-175 ME^    

Saffron extract … 30mg

(stigma) [std. to 2% safranal; 11% crocins]

Other ingredients: potato starch, vegetable oil powder, vegetable cellulose (capsule), maltodextrin, microcrystalline cellulose, vegetable stearate, ascorbic acid.

Contains milk, soybeans.

Gluten free - Non-GMO

†Colony Forming Units at time of manufacture.

^ME refers to a patented microencapsulation process that protects the probiotics for enhanced stability.

Life Extension's immune system is our body’s built-in line of defense. Coincidentally, it also reacts to harmless things in your environment, such as pollen. EpiCor®, a yeast fermentate and L. rhamnosus CRL1505, a probiotic strain, encourage multiple aspects of a healthy immune response, so you’re ready for whatever the world has for you.

EpiCor® was discovered when factory workers at a yeast fermentation plant had better work attendance than their office counterparts.

FLORASSIST® Immune & Nasal Defense Benefits

• Encourages the body’s healthy immune response
• Promotes production of immunoglobulin A (IgA), an essential part of your body’s immune defenses
• Supports healthy nasal airflow and response to things in your environment, such as pollen.

Suggested Use:

Take one (1) capsule daily, or as recommended by a healthcare practitioner.

Serving Size: 1 Vegetarian Capsule

Amount Per Serving

EpiCor®-Dried fermentate … 500mg

(from Saccharomyces cerevisiae)      

Lactobacillus rhamnosus CRL-1505 … 50mg

[providing 100 million CFU†]          

Other ingredients: vegetable cellulose (capsule), microcrystalline cellulose, corn starch, silica, stearic acid.

†Colony Forming Units at time of manufacture.

Gluten free - Non-GMO

EpiCor® is a registered trademark of Embria Health Sciences, L.L.C.

Warning: When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Do not purchase if outer seal is broken or damaged.

Keep out of reach of children.

Do not exceed recommended dose.

SAMe should not be taken by those diagnosed with bipolar disorder.

• KEEP OUT OF REACH OF CHILDREN
• DO NOT EXCEED RECOMMENDED DOSE
• Do not purchase if outer seal is broken or damaged.
• When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Helps Maintain Optimal Breast Health

Now more than ever before, women are being proactive about supporting breast health. One of the most important actions you can take is to maintain a healthy balance between “good” and “bad” estrogen. So if you’d like to proactively restore your youthful hormonal balance, try Breast Health Formula. This broad-spectrum formula provides powerful nutrients that help support healthy estrogen activity and detoxification to preserve optimal breast health.

Benefits at a Glance

• Helps maintain optimal breast health
• Supports youthful hormone balance
• Supports a healthy balance of estrogens
• Provides several botanical extracts

Maintaining Optimal Breast Health

Detrimental factors like the aging process, along with the daily bombardment of damaging environmental estrogen-like compounds, can affect the cellular structure of a woman’s breast.1-3

Research shows that specific botanical extracts can positively influence cellular status and remove some of the anxiety women face about maintaining a healthy balance of estrogens.

Promoting Healthy Estrogen Balance

Estrogen is broken down to several important metabolites in the body including the good 2-hydroxyestrone and the bad 16 alpha-hydroxyestrone. Scientists have identified nutrients like indole-3-carbinol (I3C) that can tip the delicate balance of estrogens in favor of the good form.4, 5

Women seeking to proactively restore their youthful hormonal balance can take this phytonutrient-based formula to help support healthy estrogen activity and detoxification.

Powerful Botanical Formula

Some of the active ingredients in the Breast Health Formula are:

• Phytoestrogens that function as selective estrogen receptor modifiers to help block certain estrogen receptor sites on cells, thus blocking bad estrogen from exerting its harmful effects6
• Plant lignans that boost beneficial enterolactone levels and favorably alter estrogen metabolism7-9
• Cruciferous Vegetable Extracts (such as I3C) that effectively increase 2-hydroxyestrone while reducing undesirable 16 alpha-hydroxyestrone10, 11
• Calcium d-Glucarate to safely facilitate the removal of harmful estrogen from the body12-14
• Vitamin D to restore healthy genetic regulatory switching to aging cells15

Be proactive and support optimal breast health by adding Breast Health Formula to your regimen today!

Serving Size: 2 capsules

Amount Per Serving
Vitamin D3 ... 1000IU
(as cholecalciferol)
Calcium ... 16.5mg
(as calcium D-glucarate)
Iodine ... 2mg
(as potassium iodide)
Proprietary Cruciferous Vegetable Blend ... 550mg
Broccoli super concentrate extract (seed and plant) [providing glucosinolates]; watercress 4:1 extract (whole herb); wasabi powder (rhizome)
I3C ... 100mg
(Indole-3-Carbinol)
Proprietary Enterolactone Precursors Blend ... 65mg
Flax lignan extract (seed) [providing secoisolariciresinol diglucoside (SDG)]; HMRlignan™ Norway spruce (Picea abies) lignan extract (knot wood) [std. to 90% hydroxymatairesinol potassium acetate]
Isoflavones ... 35mg
(from Novasoy® soy isoflavone concentrate)
DIM ... 14mg
(3, 3’-diindolylmethane)

Other Ingredients: vegetable cellulose (capsule), rice flour, ascorbyl palmitate, corn starch, maltodextrin.

Contains soybeans.

Novasoy® is a registered trademark of Archer Daniels Midland Company; HMRlignan™ trademark is used under license from Linnea S.A.

Caution
Do not take if pregnant or lactating. Consult your healthcare practitioner before taking this product if you have a thyroid condition, high blood calcium levels, or hormone-sensitive cancers. Individuals consuming more than 2, 000 IU/day of vitamin D (from diet and supplements) should periodically obtain a serum 25-hydroxy vitamin D measurement.

If you have a thyroid condition or are taking antithyroid medications, do not use without consulting
 your healthcare practitioner.

Warnings

• KEEP OUT OF REACH OF CHILDREN
• DO NOT EXCEED RECOMMENDED DOSE
• Do not purchase if outer seal is broken or damaged.
• When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Bone Strength Collagen Formula features a patented formulation of calcium and collagen to help maintain optimal bone health, promote bone strength and flexibility and help maintain healthy bone mineral density. Silicon from bamboo extract and dried plum extracts offer additional minerals to support bone health.

Bone Strength Collagen Formula is a good complement to resistance exercise and a comprehensive nutritional program.

Bone Strength Collagen Formula Benefits:

• Enhances bone health
• Helps maintain healthy bone mineral density
• Optimizes bone strength & flexibility

Suggested Use:

Take four (4) capsules daily in divided doses, or as recommended by a healthcare practitioner.

Serving Size: 4 Capsules

Amount Per Serving:

Vitamin D3 ... 25mcg

(as cholecalciferol)

Calcium ... 300mg

(from 3000 mg KoAct® Calcium Collagen Chelate and calcium fructoborate)

Magnesium ... 100mg

(as magnesium citrate)

Silicon ... 5mg

[from standardized Bamboo extract (stem)]

Dried Plum extract ... 100mg

(fruit) [standardized to 50% polyphenols by UV-Vis (50 mg)]

Boron ... 3mg

(calcium fructoborate as patented Fruitex B® OsteoBoron®)

Other ingredients: vegetable cellulose (capsule), vegetable stearate, maltodextrin, corn starch.

Gluten free -  Non-GMO

Warnings

• KEEP OUT OF REACH OF CHILDREN
• DO NOT EXCEED RECOMMENDED DOSE
• Do not purchase if outer seal is broken or damaged.
• When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Throughout life, cells known as osteoblasts construct bone matrix and fill it with calcium. At the same time, osteoclasts work just as busily to tear down and resorb bone. This fine balance is regulated by many factors, including systemic hormones and cytokines. Bone mass reaches its peak by the middle of the third decade of life and plateaus for about ten years, during which time bone turnover is constant, with bone formation approximately equaling bone resorption.1, 2

As our bodies age, this fine balance is lost. As the relative hormone levels shift in midlife — more drastically in women than in men — the osteoclasts gain the upper hand and bone mass begins to dwindle. Some bone is already being lost by the time women reach menopause, but the rate of loss can increase up to tenfold during the first five years after menopause.2-4

Bone density loss is not just associated with calcium deficiency, but also with an insufficient intake of a host of other nutrients5-12 including magnesium11, 12 and vitamin D3.13, 14 In order for calcium to help maintain healthy bones, adequate amounts of vitamin D3, zinc, 15, 16 magnesium, 17 manganese, 9 and other nutrients should be available so that calcium and phosphorus can be incorporated into the bone matrix. Additionally, many forms of calcium are not particularly well absorbed.18-20

While loss of bone mineral density is more commonly experienced by women, aging men can also have this issue.21 Both men and women may experience significant deficits of magnesium if they do not supplement. Bone Restore now contains 300 mg of magnesium. Magnesium is not only needed to maintain strong bones, but it is critical to promoting a healthy vascular system.22, 23 In fact, magnesium is critical for facilitating hundreds of enzymatic reactions that our bodies require to maintain optimal health.24, 25

To overcome the impediments that preclude aging adults from achieving optimal calcium status, Life Extension offers a proprietary comprehensive mineral formula called Bone Restore which has been designed to support healthy bone density and strength. Bone Restore provides 700 milligrams of elemental calcium from three different forms, along with the critically important nutrients magnesium, 17 boron, 5, 26, 27 zinc, 8, 15, 16 silicon, 28-30 manganese9 and vitamin D313, 14 needed for healthy bones.

In fact, the boron in this formula, called FruiteX B® OsteoBoron®, is a calcium/carbohydrate/boron complex, similar to what is found in fruits and vegetables and is more bioavailable than boron citrate. Scientific research has established the beneficial effects of boron on the strength of bones and joints.5, 31-34

One reason why aging people experience bone mineral density loss even though they are taking calcium supplements is that they may not be absorbing enough elemental calcium. Bone Restore provides calcium in capsule form to ensure that it breaks down fully in the digestive tract.

Calcium and other minerals are best not taken with fiber, because fiber can interfere with their absorption.35-37 There is evidence that calcium from supplements and dairy foods may inhibit iron absorption, although it has been very difficult to distinguish between the effects of calcium on iron absorption versus other inhibitory factors, such as phytate.38-40 Although current understanding of this suggests that the inhibition of calcium on absorption of iron is of short duration and the body has adaptive mechanisms.41

Calcium supplements are best taken with meals. They should always be taken with a full glass of water, juice, or other liquid to enhance solubility.42 If calcium-containing formulas are taken only once daily, they may be best taken in the evening.43

Serving Size: 4 capsules

Amount Per Serving
Vitamin D3 ... 1000IU
(as cholecalciferol)
Calcium ... 700mg
(from calcium carbonate, calcium citrate malate, calcium bisglycinate)
Magnesium ... 300mg
(as magnesium oxide)
Zinc ... 2mg
(as zinc amino acid chelate)
Manganese ... 1mg
(as manganese amino acid chelate)
Silicon ... 5mg
[from horsetail (Equisetum arvense) extract (herb)]
Boron ... 3mg
(calcium fructoborate as patented Fruitex B® OsteoBoron®)

Other ingredients: Vegetable cellulose (capsule), microcrystalline cellulose, maltodextrin, silica, modified food starch, vegetable stearate.

Malate is covered by U.S. Patent 6, 706, 904 and patents pending.

Fruitex B® and OsteoBoron® are registered trademarks of VDF Futureceuticals, Inc. U.S. Patent No. 5, 962, 049.

Warnings

• KEEP OUT OF REACH OF CHILDREN
• DO NOT EXCEED RECOMMENDED DOSE
• Do not purchase if outer seal is broken or damaged.
• When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.