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Guttides is a carefully formulated supplement that combines the regenerative power of BPC-157 with the anti-inflammatory prowess of KPV, offering a dual-action approach to wellness.
What’s Inside GUTTIDES?
BPC-157 is a peptide shown to accelerate healing, particularly in the digestive tract. BPC-157 is derived from a protein found in stomach acid and has been shown to support gut health, protect against ulcers, and improve recovery from soft tissue injuries.
BPC -157 is a 15 amino acid partial sequence of Body protection compound that was discovered and isolated in gastric juice. It increases fibroblast migration and dispersal, induces F-actin formation in fibroblasts, modulates angiogenesis, and enhances vascular expression of VEGFR2. It can be neuroprotective, cardioprotective, and counteracts the QTc prolongation induced by neuroleptics.
KPV is a tripeptide consisting of Lysine, Proline, and Valine. KPV is recognized for its ability to reduce inflammation and support the immune system by inhibiting the activation of NF-kappaB and MAP kinase inflammatory pathways and decreasing proinflammatory cytokine secretion.
It has demonstrated benefits in skin health, wound healing, and even shows promise in alleviating symptoms of inflammatory bowel diseases.
Each Guttides capsule contains 500mcg of BPC-157 and 500mcg of KPV.
GUTTIDES' Health Benefits
GUTTIDES’ systemic impact opens up a world of treatment possibilities, making it a versatile solution for a wide range of patient goals. Here are just a few examples of how our providers (and you) can implement Guttides to enhance patient outcomes:
- Gut health improvement
- Gastric reflux disease
- Antiulcer properties
- Joint pain/inflammation
- Soft tissue injury
- Autoimmune support
- Improves nerve generation
- Counteracts QT prolongation
- Acne
- Hair growth and support
Ingredients
• Body Protective Compound (as BPC-157 Arginate Salt): 500mcg
• KPV (Lysine-Proline-Valine) Peptide 500mcg
Recommended Use
Guttides can be incorporated into your patient’s daily routine with ease. The recommended dosage is one capsule per day, making it a simple addition to your overall health strategy.
BPC-157 Rapid Pro – Enhanced Fast-Acting Recovery & Gut Health Support
Description:
BPC-157 Rapid Pro is a premium oral peptide supplement featuring a higher-strength dose of BPC-157 (500 µg), formulated for rapid absorption and enhanced recovery. Designed for advanced joint, tissue, gut, and neurological support, this version includes an absorption enhancer (SNAC) to help the peptide be efficiently delivered and utilized.
Key Benefits
-
Accelerates recovery and comfort in joints, muscles, tendons, and ligaments.
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Promotes digestive health and gut–brain axis support.
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Enhances cognitive clarity, nerve resilience, and mood balance.
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Includes SNAC (absorption enhancer) for fast and efficient delivery of the active peptide.
Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 30/60
| Amount Per Capsule | Quantity |
|---|---|
| BPC-157 (as Arginate Salt) | 500 µg |
| Salcaprozate Sodium (SNAC – absorption aid) | ~3 mg |
Other Ingredients: Rice powder, microcrystalline cellulose, vegetable capsule (hypromellose).
Free From: Gluten, soy, dairy, GMOs.
Suggested Use
Take 1 capsule twice daily, at least 1 hour before or after eating or drinking anything other than water.
Frequently Asked Questions (FAQ)
What is BPC-157 Rapid Pro?
It’s a high-strength, fast-acting BPC-157 formula designed for powerful and swift support in joints, tissues, digestion, and neurological health.
What makes Rapid Pro different from the Rapid version?
Rapid Pro delivers double the BPC-157 (500 µg vs 250 µg) while also including a higher amount of SNAC for superior absorption and effect.
How does SNAC aid the formula?
SNAC helps protect BPC-157 from degradation in the stomach and enhances its passage into systemic circulation for improved efficacy.
What kind of results should I expect?
Users may experience faster recovery, improved joint comfort, and better digestive or cognitive results, especially with consistent use over time.
Is it suitable for athletic use?
BPC-157 typically isn’t part of standard drug tests, but athletes should verify with relevant organizations to ensure compliance with regulations.
Caution
-
Do not exceed the recommended dose.
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Consult a healthcare professional before use if pregnant, nursing, under 18, or if managing health conditions.
-
Discontinue use if adverse reactions occur.
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Store in a cool, dry place. Keep out of reach of children.
An exercise and caloric restriction mimetic that improves
Sirtuin and NAD+ functions. This low-dose leucine
compound is best known for its incredible enhancement
of weight loss with GLP 1’s like semaglutide.
LeuSynergy + GLP-1s has become a
foundational protocol for weight loss
and metabolism optimization.
Cellular Pathways
Delivering the right dose of Leucine decreases the amount
of NAD needed to activate SIRT-1.
* Leucine at a concentration of 0.5mM was shown to decrease the kM of NAD by 50%
With Leucine, LESS NAD+ is needed for SIRT-1 functions, improving NAD+ utilization in other cellular pathways.
Why this matters: SIRT-1 Downstream Effects
Stimulates caloric restriction and exercise pathways through these gene transcription factors::
PGC-1a: The core regulator of mitochondrial biogenesis, PPAR: Regulate fat oxidation, AMPK: Master regulator of cell energy, NF-kB: Inhibition leads to decreased inflammation and oxidative stress
Clinical Studies
Leucine-Resveratrol Synergy
Human Pre-diabetic Subjects Randomized:
Leucine 1.1 g + Resveratrol 50mg Twice Daily vs. Placebo
• OGTT and 60 min glucose and insulin concentration
• Reduced insulin resistance by 33%
• Significant improvement and insulin/glucose dynamics
Weight Loss – Fat Oxidation – Insulin Sensitivity
Synergy with GLP-1s: Semaglutide, Tirzepatide, Liraglutide
Studies show 15% reduction in body weight when semaglutide was accompanied by caloric restriction and exercise. Using an exercise mimetic like LeuSynergy is foundational in weight loss and metabolic health outcomes.
Insulin Independent Pathways for Glucose Disposal
GLP-1: Increase in GLUT4 expression by activating AMPK
LeuSynergy: Increase in GLUT4 expression through SIRT1 deacetylation of PGC-1a
Improved Fat Oxidation
GLP-1: Direct effects on hepatocytes by activating genes involved in beta-oxidation of fatty acids
LeuSynergy: Activation of PGC-1a and PPAR resulting in an increase in fatty acid oxidation and oxidative phosphorylation
Oxidative Stress and Pancreatic Beta Cell Protection
GLP-1: Reduced oxidative stress in pancreatic islets. Increases
B-cell mass by regulating cell kinectics and suppressing oxidative and ER stress, and amerlioration of glucolipotoxicity.
LeuSynergy: SIRT1 deacetylation and inhibition of NF-kB protecting beta cells from oxidative stress and inflammatory cytokines.
Ingredients
• Leucine 1.1 grams
• Resveratrol 50mg
• Pyroxdine 15mg
Recommended Use
Take 2 tablets in the morning and 2 tablets 90 minutes after lunch.
As an alternative to statins, it leverages the synergy of leucine and nicotinic acid with polymethoxylated flavones and tocotrienols to improve lipid biomarkers, fat oxidation, and circadian rhythms. SIRT genes are targeted due to their signaling to regulate fat oxidation, mitochondrial function, inflammatory cytokines, and antioxidant pathways. SIRT genes depend on NAD+ levels to be activated through AMPK’s nutrient-sensing capabilities. This axis between SIRT1/NAD+/AMPK is the focus of Sytrinol® LNA and its ability to improve metabolism and dyslipidemia.
Ingredients
• Sytrinol® 300mg
+ Nobiletin: Tangerentin 270mg
+ Tocotrienols 30mg
• Leucine 1,100mg
• Nicotinic Acid 75mg
Recommended Use
Take 3 capsules with dinner daily.
Sytrinol®
+ A patented combination of polymethoxylated flavones and tocotrienols.
+ Nobiletin was shown to increase hepatic fatty acid oxidation, decrease
fatty acid synthesis and decrease inflammatory gene transcription factors. (1)
+ Nobiletin was found to enhance circadian rhythms to protect against
metabolic syndrome. (2)
+ Tocotrienol similar to statins work on HMG-CoA reductase. (4)
+ Human trials with Sytrinol® showed a decrease in LDL, Triglycerides,
Leucine and Nicotinic:
+ Leucine at low doses (1.0-1.5g) was found to activate SIRT-1 by
lowering the km of NAD+. Improving endogenous NAD+ utilization. (3)
+ Low dose leucine was found to decrease nicotinic acid dose by 95% and still get same therapeutic outcomes without the side effects. (4)
+ Leucine and nicotinic acid works on the same mechanisms as caloric restriction and exercise to activate the SIRT/NAD+/AMPK axis to improve vasodilation, lower lipids, and decrease inflammation and foam cell production. (4)
Synergy with GLP-1 + GIP: Sytrinol®LNA
Therapy with a focus on reducing cardiovascular risk.
Combining GLP-1, Growth hormone secretagogues, and mitochondrial compounds to converge on key metabolic pathways.
Tirzepatide (GLP-1 + GIP) + Sytrinol®LNA
GIP component improves healthy expansion of white adipose tissue to prevent spillover of dietary lipids that can cause ectopic lipid accumulation.
Tirzepatide shown to reduce Triglycerides and VLDL
Overview
iCell Water™ is an advanced cellular hydration and performance formula designed to optimize cell signaling and volume through osmolyte balance. By combining neutral amino acid osmolytes and creatine, it supports intracellular hydration, muscle preservation, and cellular efficiency. It’s particularly beneficial for individuals on GLP-1 therapy or those seeking improved recovery, muscle maintenance, and overall vitality.
Key Benefits
- Promotes optimal cellular hydration and osmotic balance
- Helps preserve muscle tissue and prevent muscle loss
- Enhances strength, endurance, and recovery
- Improves cell signaling and protein metabolism
- Supports energy and cardiovascular performance
How It Works
iCell Water™ modulates cellular volume to enhance energy production and hydration efficiency. Its neutral amino acid osmolytes and creatine act on sodium and chloride-dependent transport systems to increase intracellular water and maintain cell structure.
Cellular Pathways
- Creatine acts as an osmolyte via the CT1 transporter, increasing cell water and ATP production.
- Glutamine promotes hepatocyte swelling through sodium-dependent uptake, activating regulatory volume decrease (RVD) mechanisms.
- Alanine, Leucine, and Glycine enhance osmotic pressure and cell expansion through Na⁺/K⁺/Cl⁻ channels.
Why It Matters
Muscle function is a key marker of longevity and reduced mortality risk. Intracellular hydration directly affects muscle performance, protein synthesis, and recovery. Studies show that higher intracellular water levels improve strength, endurance, and overall performance, while dehydration leads to decreased power and muscle efficiency.
Research Highlights
- Higher intracellular water correlates with better muscle strength and reduced fatigue.
- Intracellular water is a major predictor of athletic performance.
- Loss of intracellular water impairs power and grip strength.
Synergy with GLP-1 and Sermorelin
GLP-1 + iCell™
GLP-1 therapy may reduce thirst and cellular hydration, indirectly leading to muscle loss. iCell Water™ helps maintain hydration and muscle cell volume, preventing catabolism and supporting lean tissue during GLP-1 use.
Sermorelin + iCell™
Sermorelin enhances protein synthesis, while iCell™ inhibits protein degradation by expanding cell volume. Together, they synergistically improve muscle repair, strength, and endurance for optimal recovery.
Supplement Facts
| Supplement Facts | |
|---|---|
| Serving Size | 2 Scoops (23.68 g) |
| Servings Per Container | 20 |
| L-Alanine | 5 g † |
| Creatine Monohydrate | 5 g † |
| Taurine | 5 g † |
| Glycine | 4 g † |
| L-Glutamine | 3 g † |
† Daily Value not established.
Other Ingredients: Silicon Dioxide
Suggested Use
Mix 2 scoops in 64 ounces of water. Consume daily for best results.
Product Facts
- Per Bottle: 20 servings
- Serving Size: 2 scoops (23.68 g)
- Directions: Take two scoops daily, mixed with 64 oz of water
- Form: Powder
- Flavor: Unflavored
Caution
Consult your physician before use if you are pregnant, nursing, taking medication, or have a medical condition. Keep out of reach of children.
Highlights
- Supports muscle, joint, and cellular hydration
- Enhances performance and endurance
- Works synergistically with GLP-1 and Sermorelin
- Free from artificial sweeteners and additives
BPC-157 Delayed – Steady, Lower-GI Support for Tissue, Digestive & Joint Health
Description:
BPC-157 Delayed is a thoughtfully designed delayed-release oral peptide supplement delivering 250 µg of BPC-157 (Body Protective Compound) per capsule. Enhanced with an absorption booster (SNAC), this formulation is crafted to release gradually in the lower gastrointestinal tract for sustained support of joint, digestive, tissue, and neurological wellness.
Key Benefits
-
Offers steady, long-term support for joints, tendons, muscles, and ligament repair.
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Helps maintain digestive balance and supports the gut-brain connection.
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Encourages neurological clarity and nerve health through balanced signaling.
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Promotes improved circulation via nitric oxide pathway support.
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Gradual release provides consistent absorption and extended benefit over time.
Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 60
Other Ingredients: Rice powder, microcrystalline cellulose, vegetable capsule (hypromellose, gellan gum).
Free From: Gluten, soy, dairy, GMOs.
Suggested Use
Take 1 capsule twice daily—morning and evening—for consistent, round-the-clock support, or follow your healthcare professional’s guidance.
Frequently Asked Questions (FAQ)
What is BPC-157 Delayed?
A delayed-release peptide supplement designed for slow, steady absorption in the lower digestive tract, delivering 250 µg of BPC-157 per capsule with SNAC to support absorption.
How does it differ from Rapid?
Both contain the same active dose and absorption enhancer, but Rapid releases in the upper GI tract for quicker effects, while Delayed is designed for sustained, gradual uptake further down the intestine.
What benefits does it provide?
It supports joint and tissue health, digestive integrity, neurological function, and vascular health through nitric oxide pathways, offering balanced and prolonged wellness support.
When might changes be noticed?
Some users report improvements in comfort or digestion within days or weeks, with more consistent and noticeable results emerging over time.
Is it a good oral form of BPC-157?
Yes — with SNAC aiding absorption in the lower GI tract, this delayed-release format offers reliable, practical, and steady delivery throughout the day.
Is it safe?
Yes. Physician-formulated, third-party tested, and manufactured following GMP standards. However, consult a healthcare professional if you have health conditions or are taking medications.
Caution
-
Do not exceed the recommended dose.
-
Pregnant or nursing individuals, those under 18, or anyone with health conditions should seek healthcare advice before use.
-
Discontinue use if adverse reactions occur.
-
Store in a cool, dry place. Keep out of reach of children.
| Amount Per Capsule | Quantity |
|---|---|
| BPC-157 (as Arginate Salt) | 250 µg |
| Salcaprozate Sodium (SNAC – absorption aid) | ~1.5 mg |
Butyrate prodrug, tributyrin, is proven to overcome the pharmacokinetic drawbacks of butyrate supplementation. Butyrate can epigenetically regulate gene expression. nuButyrate has the only regulatory compliant tributyrin on the market clinically substantiated to be bioavailable in the colon and to show improvement in boosting butyrate-producing bacteria. Butyrate has been shown to neutralize reactive oxygen species by the overexpression of glutathione peroxidase, causing the inhibition of NF-kB, leading to the activation of antioxidant enzymes and impairing inflammatory genes. nuButyrate is crucial to immune, gut, and metabolic health.
Ingredients
• Tributyrin (as CoreBiome®): 500 mg
Recommended Use
Take 2 capsules daily.
Helping support digestive and gastrointestinal health
through impacting gene expression, Tributyrin is the only
form to be clinically substantiated bioavailability in the
colon. It supports immune health by supporting tight
junctures in the intestinal lining normalizing inflammatory
responses in the gastrointestinal tract.
Butyrate prodrug Tributyrin is proven to
overcome the pharmacokinetic drawbacks of
butyrate supplementation while eliminating
bad smell and taste.
Cellular Pathways
The overexpression of GPx causes the blocking of the
NF-kB cascade, resulting in the attenuation of the
inflammatory response by impairing the expression of
NF-kB inflammatory genes.
Butyrate induces maturation and expansion of colonic
regulatory T cells
PPARy, strongly expressed in the colon, controls the energy
production required for microbiome homeostasis through
fatty acid oxidation.
Why this matters:
3 days of Abx administered by oral gavage resulted in an
early complete loss of bacterial groups. Despite outgrowth of
several resistant organisms, cecal contents from abx-treated
mice lost the ability to produce SCFAs from inulin and lost HIF
expression, both of which are restored by butyrate administration.
Butyrate is a potent activator of AMPK in colonic cell lines.
*Kelly, C. Crosstalk between Microbiota-Derived Short-Chain Fatty Acids and Intestinal Epithelial
HIF Augments Tissue BarrierFunction. Cell Host Microbe. 2015; 17(5): 662–671
Clinical Studies
nuButyrate™ Results
Butyrate prodrug Tributyrin is proven to overcome the pharmacokentic drawbacks of butyrate supplementation while eliminating bad smell and taste. It has been clinically substantiated bioavailability in the colon.
* who performed the study?
• Faecalibacterium prausnitzii increased 41% over placebo
• Anaerostipes increased 67% over placebo
• Both bacteria are butyrate producers and their benefits are associated with butyrate production (healthy microbiome, immunity, healthy inflammatory response, etc.)
Tributyrin (as CoreBiome®)
• Is the #1 selling SCFA on the market
• Has clinically substantiated bioavailability in the colon
• In a 48-hour study using a gastrointestinal model [and that was repeated in a four-week study], CoreBiome® limited IL6, TNF-alpha and measurements of epithelial function through TEER (transepithelial electrical resistance), suggesting that it may support gut barrier function
• Is the ONLY SCFA with marketable claims
Synergy with Larazotide, Guttides (BPC-157 + KPV):
Critical component of GI protocols including Guttides (BPC-157 + KPV), Larazotide and low dose pentosan polysulfate.
Larazotide + nuButyrate™
Larazotide protects the gut by improving and repairing tight junctions providing gut permeability protection. Larazotide improves the structure and integrity of the gut while nubutyrate works on creating the optimal environment through immune and inflammation modulation.
Guttides + nuButyrate™
The combination of gut health peptides BPC-157 and KPV improve inflammation and mucosal barrier integrity. nuButyrate is commonly used in conjunction to further improve the GI inflammatory state.
Dive into purity
Codeage Wild-Caught Marine Collagen powder supplement offers hydrolyzed collagen of types 1 & 3, sustainably sourced from North American ocean white fish. Packed with 18 amino acids, this pure fish collagen powder supplement provides a 50-day supply in each canister. This marine collagen powder is also ideal for those seeking a meatless collagen supplement.
- Codeage Wild-Caught Marine Collagen supplement is sustainably sourced from deep-ocean white fish in North American cold waters, providing a high concentration of type 1 & 3 collagen in a convenient powder format.
- This marine collagen powder supplement delivers 18 essential and non-essential amino acids, offering comprehensive support to your overall health and well-being.*
- This pure fish collagen supplement formula is uncompromising in its purity. This marine collagen peptides supplement is non-GMO, dairy-free, and gluten-free. This hydrolyzed fish collagen contains zero carbs, with no additives, preservatives, or sulfites, making it a clean and wholesome addition to your daily routine. This meatless collagen is also shellfish-free.
- Each container of this hydrolyzed collagen powder formula provides a generous 50-day supply designed to integrate into your busy life seamlessly; its versatility allows you to mix it into beverages, protein shakes, or your favorite recipes.
- Codeage Wild-Caught Marine Collagen powder is manufactured in the USA with global ingredients in a cGMP-certified facility for quality and purity.
Ingredients
Wild-Caught, Cold Water White Fish Collagen.
Amino acid profile (average milligrams per serving): Alanine 702 mg, Arginine 684 mg, Aspartic Acid 459 mg, Glutamic Acid 1116 mg, Glycine 1836 mg, Histidine 99 mg, Hydroxylysine 36 mg, Hydroxyproline 594 mg, Isoleucine 108 mg, Leucine 252 mg, Lysine 270 mg, Methionine 63 mg, Phenylalanine 162 mg, Proline 1170 mg, Serine 243 mg, Threonine 135 mg, Tyrosine 45 mg, Valine 189 mg. Average milligrams per serving naturally occurring; absolute values may vary. Contains 8 of 9 essential amino acids. Not a significant source of protein. Collagen protein does not count toward the FDA recommended Percent Daily Value for protein because it lacks one essential amino acid: tryptophan. Packaged by weight, not volume. Settling may occur.
SUGGESTED USE.
Adults take 1 scoop with 8-12 ounces of water or your favorite beverage or as directed by a qualified healthcare practitioner.
CAUTION: Do not exceed recommended dose. Pregnant, nursing mothers, children under 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Please use caution if you have allergies or sensitivities to any of the listed ingredients. Keep out of reach of children and pets. Do not use if safety seal is damaged or missing. Store in a cool dry place. Use this product as a food supplement only. Do not use for weight reduction.
| Supplement facts | ||
| Serving Size: 1 Scoop (About 9 g) | ||
| Servings Per Container: Approx. 50 | ||
| Amount Per Serving | %Daily Value | |
| Wild-Caught, Cold Water White Fish Collagen |
9000 mg | ** |
| **Daily Value (DV) not established |
||
|
Typical Amino Acid Profile |
|||||
| (Average milligrams per serving naturally occurring; absolute values may vary.) |
|||||
| Alanine | 702 mg | Hydroxylysine | 36 mg | Phenylalanine** | 162 mg |
| Arginine | 684 mg | Hydroxyproline | 594 mg | Proline | 1170 mg |
| Aspartic Acid | 459 mg | Isoleucine** | 108 mg |
Serine |
243 mg |
| Glutamic Acid | 1,116 mg | Leucine** | 252 mg |
Threonine** |
135 mg |
| Glycine | 1,836 mg | Lysine** | 270 mg | Tyrosine | 45 mg |
| Histidine** | 99 mg |
Methionine** |
63 mg | Valine** | 189 mg |
| **Essential Amino Acids. Contains 8 of 9 essential amino acids. |
|||||
Other ingredients
100% collagen peptides from wild-caught cold water white fish in North America.
Contains: Fish (white fish).
Allergen warning: Fish (white fish).
Показано 8/22
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