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MegaPre™ – Precision Prebiotic Powder, 5.5 oz (144.5 g)
Microbiome Labs
Clinically Targeted Prebiotic to Restore Keystone Gut Bacteria
MegaPre™ is a cutting-edge Precision Prebiotic™ powder that selectively nourishes beneficial gut bacteria — without feeding opportunistic microbes. Unlike general fiber products, MegaPre™ contains clinically tested oligosaccharides and organic kiwifruit powder that promote the growth of keystone species like Akkermansia muciniphila, Faecalibacterium prausnitzii, and Bifidobacteria. These bacteria play a foundational role in gut barrier integrity, immune regulation, and short-chain fatty acid (SCFA) production.
This 5.5 oz jar contains 30 servings of unflavored, mixable powder — ideal for daily gut support and easy integration into Total Gut Restoration protocols.
Key Benefits
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Selectively feeds critical keystone bacteria (not broad-spectrum)
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Enhances microbial diversity and butyrate production
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Supports healthy gut lining and mucosal immunity
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Works synergistically with MegaSporeBiotic™
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Easy-to-mix, unflavored formula for customizable use
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Gluten-free, non-GMO, no artificial ingredients
Science Behind MegaPre™
Keystone species are essential for gut health, but modern lifestyles (processed foods, antibiotics, stress) often deplete them. MegaPre™ helps rebuild this foundation through a proprietary blend of:
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Galactooligosaccharides (Bimuno®) – Shown to support Bifidobacteria and enhance SCFA production
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Xylooligosaccharides (PreticX®) – Clinically proven to improve microbial diversity and support bowel regularity
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Organic Kiwifruit Powder (Livaux® and ACTAZIN®) – Rich in polyphenols and fiber to support gut motility and microbial balance
Together, these ingredients provide targeted nourishment for the microbiome — without causing bloating or feeding unwanted bacteria.
Supplement Facts
Serving Size: 1 scoop (4.8 g)
Servings Per Container: 30
Net Weight: 5.5 oz (144.6 g)
| Nutrient | Amount per Serving |
|---|---|
| Proprietary Functional Fiber Blend | 4 g |
| – Galactooligosaccharides (Bimuno®) | — |
| – Organic Xylooligosaccharides (PreticX®) | — |
| – Organic Kiwifruit Powder (Livaux®, ACTAZIN®) | — |
| Calories | 20 |
| Total Carbohydrate | 4 g (1% DV) |
| Dietary Fiber | 1 g (4% DV) |
| Total Sugars | <1 g |
Other Ingredients:
None. Unflavored. Free of sweeteners, colors, and artificial additives.
Contains: milk (from lactose-derived GOS).
(Dairy-free version available separately.)
Suggested Use
Ages 4 and up:
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Start with ½ scoop per day during the first week
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Increase to 1 scoop daily, or as directed by your healthcare provider
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Mix into 8–12 oz of room temperature water, smoothie, or non-hot liquid
Children under 4: Use only under medical supervision.
Frequently Asked Questions (FAQ)
Q: Is MegaPre™ a fiber supplement?
A: Not exactly. While it contains fiber, it's a targeted prebiotic designed to support specific beneficial microbes rather than general digestion.
Q: What does it taste like?
A: It’s unflavored and mixes well with water, smoothies, or juice. No sweetness or added flavor.
Q: Can I take it with MegaSporeBiotic™?
A: Yes. It’s highly recommended as part of Microbiome Labs’ Total Gut Restoration protocol, supporting long-term microbial shifts.
Q: Is it suitable for people with sensitive digestion?
A: Yes. MegaPre™ is well-tolerated, even in individuals who react poorly to traditional prebiotics. Start with a half dose to assess tolerance.
Overview
Berberine 500 mg 90 capsules is a high-potency botanical formula designed to support healthy glucose metabolism, lipid balance, metabolic function, and gut microbiome health. Each capsule provides 500 mg of berberine HCl standardized to 97%, sourced from Indian barberry root (Berberis aristata), delivering a concentrated and practitioner-grade form of this well-studied plant compound.
Berberine is widely used in metabolic support supplements because of its role in supporting healthy blood sugar balance already within normal limits, lipid metabolism, and cellular energy regulation. This formula is ideal for those looking for a berberine HCl 500 mg supplement with clinically relevant potency and clean capsule delivery.
Key Benefits
- Provides 500 mg of berberine HCl (97%) per capsule
- Supports healthy blood glucose metabolism already within normal limits
- Promotes healthy cholesterol and triglyceride balance
- Supports AMPK activity and cellular energy regulation
- Helps support gut microbiome balance and digestive health
- Botanical metabolic support in a concentrated practitioner-style formula
- Well suited for cardiometabolic wellness routines
Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 90
| Ingredient | Amount Per Serving | % Daily Value |
|---|---|---|
| Berberine HCl 97% (from Indian Barberry) (root) (Berberis aristata) | 500 mg | Daily Value not established |
Other Ingredients: Hydroxypropyl methylcellulose, microcrystalline cellulose, rice hull concentrate, gum arabic, sunflower oil, silicon dioxide.
Ingredient Breakdown
| Ingredient | Role in the Formula |
|---|---|
| Berberine HCl 97% | Concentrated plant alkaloid used to support glucose metabolism, lipid balance, and metabolic regulation |
| Indian Barberry Root | Botanical source of berberine used in standardized metabolic support formulas |
How It Works
Berberine is a plant-derived alkaloid best known for its role in supporting glucose metabolism, lipid balance, and cellular energy pathways. One of its key mechanisms is its interaction with AMP-activated protein kinase (AMPK), an enzyme involved in regulating energy use, fat metabolism, and glucose handling at the cellular level. This is one reason berberine is frequently included in formulas aimed at metabolic balance and cardiometabolic support.
In addition to metabolic support, berberine is also relevant for gut microbiome health. Its interaction with the intestinal environment makes it useful in broader wellness strategies where digestion, microbial balance, and metabolic health overlap. This gives the formula a wider benefit profile than a simple blood sugar support product alone.
Because this formula delivers 500 mg of berberine HCl standardized to 97% per capsule, it aligns well with the strength commonly used in berberine-focused supplementation routines. For people looking for a high-strength berberine supplement for glucose support, lipid balance, and gut health, this is a strong single-ingredient option.
Suggested Use
As a dietary supplement, take 1 capsule three times daily, or as directed by a healthcare practitioner.
FAQ
What does Berberine 500 mg support?
It is designed to support healthy glucose metabolism, lipid balance, metabolic function, and gut microbiome health.
How much berberine is in each capsule?
Each capsule provides 500 mg of berberine HCl standardized to 97%.
What is the source of berberine in this formula?
The berberine is derived from Indian barberry root (Berberis aristata).
Why is berberine often used for metabolic support?
Berberine is commonly used because it supports pathways related to glucose handling, lipid metabolism, and AMPK activity, which are central to metabolic balance.
Who may consider this product?
It may be useful for individuals focused on cardiometabolic wellness, healthy blood sugar support already within normal limits, lipid balance, and gut-microbiome-related wellness strategies.
Storage
Store in a cool, dry place, tightly capped, away from light. Keep out of the reach of children. Use only if safety seal is intact. Variations in product color may occur.
RestorFlora™ – Comprehensive Gut Recovery Probiotic with Yeast & Spore-Based Bacteria, 60 Capsules
Microbiome Labs
Advanced Multi-Strain Formula for Digestive & Immune Resilience
RestorFlora™ is a broad-spectrum probiotic and gut recovery formula combining a clinically validated probiotic yeast (Saccharomyces boulardii) with three resilient spore-forming bacterial strains: Bacillus subtilis HU58™, Bacillus clausii SC-109, and Bacillus coagulans SC208. This powerful combination is designed to restore microbial balance, promote gut resilience, and support digestion and immunity — even during or after gut-disruptive events like antibiotics, food poisoning, or GI stress.
Unlike traditional probiotics that may degrade in the stomach or fail under antibiotic pressure, RestorFlora™ delivers hardy, shelf-stable strains that survive transit, colonize the gut, and maintain immune synergy.
Key Benefits
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Supports intestinal flora balance and microbiome resilience
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Helps maintain digestive comfort and motility
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Supports healthy transit time and relief from bloating, gas, cramps, diarrhea, or constipation
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Promotes gut recovery during/after gut-disrupting medications or practices
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Enhances immune system response and gut-lining integrity
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Combines yeast and bacterial strains for broader-spectrum support
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Shelf-stable, dairy-free, gluten-free, soy-free
Unique Multi-Strain Composition
Each capsule delivers a clinically studied combination of:
🦠 Saccharomyces boulardii (CNCM I-1079)
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A probiotic yeast known for use during and after antibiotic therapy
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Helps maintain intestinal barrier function and prevent overgrowth of unwanted microbes
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Extensively used to reduce the risk of antibiotic-associated diarrhea
🦠 Bacillus subtilis HU58™
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Spore-forming probiotic that resists stomach acid, activates in the intestines
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Produces key nutrients like vitamin K2 and short-chain fatty acids (SCFAs)
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Supports mucosal immunity and gut lining regeneration
🦠 Bacillus clausii (SC-109)
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Naturally antibiotic-resistant
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Helps regulate immune balance and support respiratory health
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Known to persist and colonize even under antimicrobial pressure
🦠 Bacillus coagulans (SC208)
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Assists protein digestion and carbohydrate fermentation
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Produces lactic acid to modulate gut pH
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Improves symptoms like bloating and abdominal discomfort
Supplement Facts
Serving Size: 1 capsule
Servings Per Container: 60
Probiotic Blend Total: 370 mg / 8 Billion CFU
| Strain | Amount |
|---|---|
| Saccharomyces boulardii (CNCM I-1079) | 250 mg |
| Bacillus subtilis HU58™ | 100 mg |
| Bacillus clausii SC109 | 10 mg |
| Bacillus coagulans SC208 | 10 mg |
Other Ingredients: Cellulose, hypromellose (vegetable capsule), water.
Free from: GMOs, dairy, soy, gluten, artificial additives.
Suggested Use
Ages 5+:
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Week 1: Take 1 capsule twice daily with food
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Week 2 and beyond: Take 1 capsule daily with food
Or as directed by your healthcare provider.
Children under 5: Use only under medical supervision.
No refrigeration required.
Frequently Asked Questions (FAQ)
Q: Can RestorFlora™ be used with antibiotics?
A: Yes — it is specifically designed to support the gut during and after antibiotic therapy. All strains are stable in the presence of gut-disrupting agents.
Q: How is it different from single-strain S. boulardii products?
A: RestorFlora™ goes beyond traditional S. boulardii formulas by combining yeast + multiple Bacillus strains, offering broad-spectrum support for both digestive and immune health.
Q: Is it okay for daily use?
A: Yes — it’s gentle enough for daily use and clinically well-tolerated.
Q: Can it be combined with MegaSporeBiotic™ or other Microbiome Labs products?
A: Absolutely — RestorFlora™ is often paired with M
MegaMarine™ – Clinical-Grade Omega-3 for Gut & Immune Health, 60 Softgels
Targeted Fish Oil Formulated for the Gut, Not Just the Brain
MegaMarine™ is a pharmaceutical-grade fish oil designed specifically for gut and immune health — not just general omega-3 support. It provides a potent and balanced blend of EPA, DHA, and DPA in their natural triglyceride form for optimal bioavailability. Additionally, it contains Specialized Pro-Resolving Mediators (SPMs) — powerful omega-3 derivatives that help the body resolve inflammation.
While most fish oils focus on brain or heart health, MegaMarine™ delivers the omega-3s your intestinal lining, microbiome, and immune cells need to function properly — making it ideal for individuals with compromised gut barrier, immune imbalance, or chronic inflammation.
Key Benefits
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Supports gut microbial diversity (incl. Akkermansia, Bifidobacterium, Lactobacillus)
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Promotes healthy mucosal lining and gut barrier function
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Neutralizes LPS and supports intestinal detoxification
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Aids in the resolution of inflammation via SPMs
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Improves absorption of EPA/DHA through inclusion of DPA
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Naturally flavored, clean softgel formula — no fishy aftertaste
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Certified sustainable and dolphin-safe (FOS Certified)
Science Behind MegaMarine™
Fish oil is widely known for its cardiovascular and neurological benefits — but its impact on gut health has often been overlooked. Recent studies show that omega-3s, especially EPA and DPA, help maintain the intestinal lining, reduce inflammatory signaling, and enhance microbial diversity.
EPA – Key for gut mucosal protection. Supports intestinal alkaline phosphatase, which detoxifies endotoxins like LPS and improves epithelial resilience.
DHA – Maintains phospholipid membrane fluidity in both the nervous system and the enteric nervous system of the gut.
DPA – A rare omega-3 that improves the bioavailability of EPA and DHA and helps modulate the COX inflammatory pathway.
SPMs (Specialized Pro-Resolving Mediators) – End-stage omega-3 metabolites that actively help the immune system resolve inflammation. Most people underproduce them due to stress, poor diet, or genetic limitations. MegaMarine™ includes SPMs directly in the formula.
Together, these components make MegaMarine™ one of the most complete omega-3 products available — engineered specifically for the needs of the gastrointestinal system.
Supplement Facts
Serving Size: 2 softgels
Servings Per Container: 30
| Nutrient | Amount per Serving |
|---|---|
| Total Omega-3 Fatty Acids | 1500 mg |
| – EPA (Eicosapentaenoic Acid) | 850 mg |
| – DHA (Docosahexaenoic Acid) | 450 mg |
| – DPA (Docosapentaenoic Acid) | 100 mg |
| Specialized Pro-Resolving Mediators (PRMs) | 200 mg |
| Total Fat | 2.5 g (3% DV) |
| Cholesterol | 10 mg (3% DV) |
| Calories | 25 |
| Protein | <1 g |
Other Ingredients:
Highly refined omega-3 marine oil (from anchovy, sardine, herring, mackerel, squid), natural lemon flavor, mixed tocopherols (antioxidants), capsule (bovine gelatin, glycerin, water).
Contains fish.
Suggested Use
Ages 8 and up:
Take 2 softgels daily with food, or as recommended by your healthcare practitioner.
No refrigeration required. Store in a cool, dry place.
Frequently Asked Questions (FAQ)
Q: What makes MegaMarine™ different from regular fish oils?
A: Most fish oils are formulated for heart or brain support. MegaMarine™ is specifically engineered for gut health, with a high EPA content, added DPA for bioavailability, and SPMs to promote inflammation resolution.
Q: Why are SPMs important?
A: Specialized Pro-Resolving Mediators (SPMs) help your immune system actively resolve inflammation rather than simply suppress it. MegaMarine™ includes them preformed, which bypasses conversion limitations caused by stress, genetics, or diet.
Q: Can this help with leaky gut or GI inflammation?
A: Yes. The combination of EPA, DPA, and SPMs helps support gut barrier integrity, reduce inflammatory signaling, and improve detoxification of endotoxins like LPS.
Q: Is this product sustainable?
A: Yes. MegaMarine™ is Friends of the Sea (FOS) certified, meeting strict environmental and sustainability standards, including dolphin-safe practices.
Glutamine-rich, prebiotic formula supports GI and immune function
Benefits and Features
Powerful support for your entire GI tract and gut microbiota with a blend of supporting nutrients, prebiotics, and glutamine.
Detail Overview
GastroThera™ provides extensive support for the entire GI tract by addressing energy requirements of the intestinal mucosa, structural composition of intestinal and colonic cells, microorganism balance, and production of protective intestinal mucus secretions.† GastroThera™ augments the actions of MultiThera® multivitamin formulas with the amino acid glutamine, the primary fuel for intestinal cell function, to help meet the high energy demands of the GI tract, liver, and immune system during periods of physiological stress and transport ammonia to the kidneys for excretion.† Acacia and inulin add soluble fibers that are readily fermentable into short-chain fatty acids that support the growth of beneficial bacteria, assist water absorption, and support colonic cell function.† N-Acetyl-D-Glucosamine helps form intestinal mucous secretions that protect intestinal tissues and help food pass through the GI tract.† GastroThera™ can be taken regularly or periodically for nutritive support of GI function and is often used with probiotic supplementation. The powder is neutral in taste and readily soluble in water.
SUPPLEMENT FACTS
| Serving Size 6 Capsules | ||
| Amount Per 6 Capsules | % Daily Value | |
|---|---|---|
| Calories | 20 | |
| Total Carbohydrate | 1 g | <1%** |
| L-Glutamine (free form) | 3.75 g | * |
| Acacia (Acacia senegal)(bark exudate gum) | 375 mg | * |
| Inulin (chicory extract)(root) | 187 mg | * |
| N-Acetyl-D-Glucosamine | 187 mg | * |
| * Daily value not established **Percent Daily Values are based on a 2,000 calorie diet |
||
Other Ingredients:
Vegetarian capsule (hydroxypropyl methylcellulose, water), ascorbyl palmitate, and silicon dioxide.
Suggested Use
Adults: 6 capsules daily or as directed by a healthcare professional. May be taken with food or between meals. Children: As directed by a healthcare professional
Allergy Statement
Made without common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, soybeans, and sesame. Non-GMO, Vegan, No synthetic colors or flavors.
Caution
Consult your physician If you are pregnant or nursing, or have a medical condition, or taking prescription drugs, or under the age of 18 years. KEEP OUT OF REACH OF CHILDREN.
Mega IgG2000™ Powder – Dairy-Free Immunoglobulin Concentrate, 60 g
Immune and Gut Barrier Support in a Pure, Powdered Form
Mega IgG2000™ Powder is a purified, dairy-free immunoglobulin concentrate designed to support gut barrier function, immune regulation, and gastrointestinal detoxification. Unlike colostrum-based supplements, Mega IgG2000™ is derived from bovine serum and contains no lactose, casein, or β-lactoglobulin — making it suitable for individuals with dairy sensitivities.
This powdered version offers flexible dosing and is ideal for individuals who prefer non-capsule formats or need tailored immune and digestive support as part of their gut restoration protocol.
Key Benefits
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Supports gut barrier integrity and mucosal immune function
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Helps bind and neutralize endotoxins (such as LPS) and microbial debris
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Promotes immune balance without overstimulation
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Enhances nutrient absorption and supports healthy metabolism
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Dairy-free, casein-free, β-lactoglobulin-free
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Mixes easily into cold liquids
Immunoglobulin Profile
Mega IgG2000™ contains three key antibodies:
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IgG (Immunoglobulin G): The most abundant antibody in circulation, essential for long-term immune defense.
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IgM (Immunoglobulin M): The first line of defense against unfamiliar antigens.
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IgA (Immunoglobulin A): Found in mucosal areas (GI tract, sinuses, lungs), saliva, and tears — supports local immunity.
These immunoglobulins act within the gut lumen to capture and clear harmful substances before they can enter systemic circulation.
Supplement Facts
Serving Size: 1 scoop (2 g)
Servings Per Container: 30
| Ingredient | Amount per Serving |
|---|---|
| Serum-derived immunoglobulin concentrate (ImmunoLin®) | 2 g |
| — of which IgG | 900 mg |
| Protein | 2 g |
| Calories | — |
Other Ingredients: None
Suggested Use
Ages 2 and up:
Take 1 scoop daily, with or without food, or as directed by your healthcare practitioner.
Mix into 16 oz of cold water or preferred liquid and stir for at least 20 seconds.
Drink plenty of fluids throughout the day.
Children under age 2: Use only under medical supervision.
BPC-157, a peptide that is renowned for its healing properties, particularly in accelerating the repair of tendons, muscles, nerves, and ligaments. It exhibits anti-inflammatory effects that help reduce swelling and pain, aiding in quicker and more comfortable recovery.
Additionally, its potential neuroprotective and
gut health benefits contribute indirectly to
overall well-being and recovery processes.
Cellular Pathways
BPC-157
• increases fibroblast migration and dispersal
• induces F-actin formation in fibroblasts
• enhances vascular expression of VEGFR2.
• NO pathway and FAK pathway for vascular response due to injury
Why this matters:
When injuries occur or repair is needed, decreasing inflammation and formation of new blood vessels is required to help the tissue heal. BPC-157 is multi-faceted in helping healing tissues and decreasing recovery times.
Clinical Studies
The promoting effect of pentadecapeptide
BPC-157 on tendon healing involves
tendon outgrowth, cell survival, and cell
migration.
The activation of migration and spreading can be strengthened by the observation of increased F-actin formation in tendon fibroblasts after BPC-157 treatment. BPC-157 was further proven in the present study to be capable of activating the phosphorylation levels of FAK and paxillin in tendon fibroblasts.
Synergy with GLP-1, Sermorelin:
BPC-157 + PPS for inflammation and pain
BPC-157 exerts anti-inflammatory effects by suppressing pro-inflammatory cytokines and promoting tissue repair, while PPS modulates glycosaminoglycan synthesis and stabilizes the extracellular matrix. Together, they enhance tissue regeneration, inhibit inflammatory signaling pathways, and modulate pain transmission, offering a comprehensive approach to alleviate inflammation and pain.
BPC-157 + Sermorelin for Injury recovery and prevention
Sermorelin’s optimization of growth hormone secretion facilitates tissue repair, while BPC-157’s enhancement of growth hormone receptor density synergistically complements this effect, potentially improving tissue healing and regeneration.
MegaGuard™ is a novel digestive aid that combines licorice polyphenols, cleansing artichoke leaf extract, and soothing ginger to promote normal digestion, regulate stomach acid, maintain healthy H. pylori levels, and reduce occasional digestive discomforts such as gas and bloating. With the power of these herbs combined, MegaGuard™️ provides unique and comprehensive digestive support, bowel regularity, and gastric balance.*
Suggested Use: Ages 8+: Take one capsule with lunch and dinner, or as directed by your healthcare practitioner.
Serving Size: 1 Capsule
Amount Per Serving
Artichoke leaf extract ... 320mg
Gutgard® licorice flavonoids ... 75mg
Ginger root extract ... 30mg
(20% gingerols)
Other Ingredients: Cellulose, vegetable capsule (water and cellulose).
If you are pregnant or nursing; taking any medication; have a medical condition, consult your doctor before using this product. Keep out of reach of children. Do not use if safety seal is broken or missing.
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