Enzymes

Microbial-based enzymes for basic digestive support

Benefits and Features

These digestive enzymes help you digest a full range of foods, including protein, fats, carbs, sugar, and fiber^†. They may support enhanced absorption of the nutrients in your food and supplements and alleviate bloating, fullness, or discomfort associated with occasional indigestion and gas.^† 

Detail Overview

Inadequate digestive enzymes—amylase, lactase, lipase, cellulase, and neutral protease—can have an impact on digestive function, leading to occasional bloating, flatulence, or gastrointestinal discomfort. Each enzyme in Digestive Enzymes has a specific role to play that ultimately can help the body better absorb nutrients from food and supplements.

SUPPLEMENT FACTS

Enzyme combination to disrupt biofilm matrix

Benefits and Features

• In vitro testing demonstrates significant anti-biofilm activity^†
• Helps degrading bacterial and yeast cell wall structures^†
• Encourages healthy intestinal microbial communities^†

Biofilms are protective encasements formed by microorganisms making them highly resistant to antimicrobials. Ther-Biotic® InterFase^® is a unique enzyme formulation designed to break up the biofilm matrix that embeds the GI organisms.^†

Detail Overview

Biofilm consists of microorganisms encased within a self-produced matrix of exopolysaccharides and exoproteins that strongly adheres to interfaces and resists dislodgement. Microorganisms residing within biofilms are highly resistant to antimicrobials including antibiotics and bacteriocins produced by probiotics. Ther-Biotic® InterFase^® is a unique enzyme formulation that is specially designed to disrupt the biofilm matrix that embeds gastrointestinal organisms.^† Enzymes in Ther-Biotic® InterFase^® are selected for their ability to lyse the extracellular polymers commonly found in biofilm as well as degrade bacterial and yeast cell wall structures.^† The enzyme blend in Ther-Biotic® InterFase^® was developed using in vitro testing of antibiofilm activity and was found to have significant antibiofilm activity resulting in meaningful degradation of undesirable biofilm communities.^† Ther-Biotic® InterFase^® is intended for use in conjunction with efforts to support normal gastrointestinal function and microbiota.^† As an adjunct, it is best combined with the use of a high-strength, broad-spectrum, multispecies probiotic formulation and a prebiotic to encourage the formation of healthy intestinal microbial biofilm communities.^†

The capsules should be taken away from meals to maximize the enzyme effects.

SUPPLEMENT FACTS

MegaMycoBalance™ – Targeted Yeast & Fungal Balance Support, 180 Softgels

Microbiome Labs

Clinically Formulated Support for Yeast Balance in the Gut and Beyond

MegaMycoBalance™ is a specialized formula designed to support healthy yeast and fungal balance throughout the body, with a particular focus on the digestive tract. It features two key active ingredients — undecylenic acid and bee propolis — known for their antifungal activity and ability to maintain microbial equilibrium.

By helping to manage yeast levels in the gut, MegaMycoBalance™ can also support balanced microflora in the vaginal, oral, and skin microbiomes, all of which are influenced by gut health. This makes it an ideal part of antifungal protocols, gut restoration plans, or maintenance routines after antibiotic or high-sugar exposure.

Key Benefits

• Helps maintain healthy yeast and fungal levels in the GI tract

• Disrupts fungal biofilms and inhibits yeast-to-hyphae transformation

• Supports microbial balance and immune function in the gut

• Promotes healthy vaginal flora by modulating gut-based yeast activity

• May aid in managing chronic or recurrent fungal overgrowth symptoms

• Gradual dose escalation for increased tolerance and flexibility

Active Ingredient Science

Undecylenic Acid
A powerful antifungal fatty acid derived from castor bean oil. It inhibits yeast cell growth and biofilm formation, and may help prevent Candida albicans from converting into its aggressive filament (hyphal) form that penetrates the intestinal wall.

Bee Propolis (70% extract)
A natural resin used by bees to protect hives from microbial threats. Rich in bioflavonoids like pinocembrin, galangin, and pinobanksin, bee propolis has been shown to help maintain fungal balance by inhibiting the growth of common yeast species.

Together, these ingredients deliver a dual-action antifungal effect that targets both active yeast and protective biofilms — a critical part of managing difficult or persistent fungal imbalances.

Supplement Facts

Serving Size: 6 softgels
Servings Per Container: 30

Other Ingredients:
Olive oil, bovine gelatin, glycerin, purified water, beeswax, sunflower lecithin.
Contains: bee products.

Suggested Use

Ages 8 and up:

• Start with 1 softgel daily for 5 days

• Gradually increase by 1 softgel every few days

• Maximum dosage: 6 softgels daily, or as recommended by your healthcare practitioner

Children under 8: Use only under medical supervision.
Best taken with or without meals. Drink plenty of water throughout the day.

Frequently Asked Questions (FAQ)

Q: What symptoms may indicate a need for yeast balance support?
A: Bloating, brain fog, skin irritation, recurrent vaginal yeast issues, sugar cravings, or white coating on the tongue can all suggest fungal imbalance.

Q: Can I combine MegaMycoBalance™ with probiotics or gut protocols?
A: Yes. It works well alongside MegaSporeBiotic™, Mega IgG2000™, or MegaMucosa™ as part of a total gut restoration or Candida protocol.

Q: Does this product kill all yeast?
A: No. It supports balance, helping reduce overgrowth while preserving the beneficial functions of commensal yeasts.

Q: How long can I use it?
A: Typical protocols last 4–8 weeks, but your practitioner may recommend longer use depending on your needs.

FODMATE™ – Targeted Enzyme Support for FODMAP Digestion, 120 Capsules

Microbiome Labs

Digestive Support for High-FODMAP Foods

FODMATE™ is an advanced digestive enzyme formula designed to support the breakdown of high-FODMAP foods and ease occasional digestive discomfort. It helps address symptoms such as bloating, abdominal discomfort, gas, and occasional constipation often associated with fermentable carbohydrates. FODMATE™ is ideal for short-term use in conjunction with a low-FODMAP diet or as targeted support when consuming high-FODMAP foods.

Key Benefits

• Supports digestion of fermentable carbohydrates (FODMAPs)

• Helps reduce occasional bloating, gas, and abdominal discomfort

• Enables continued intake of nutrient-rich, plant-based foods

• Supports adherence to restrictive diets without excessive food elimination

• May ease the transition away from low-FODMAP diets during microbiome restoration

Supplement Facts

Serving Size: 2 capsules
Servings Per Container: 60

Other Ingredients:
Cellulose, vegetarian capsule (cellulose and water)

Suggested Use

Adults and children age 8 and older: Take 2 capsules with a meal, 2–3 times per day or as directed by your healthcare practitioner.

Children under 8: Consult a healthcare practitioner before use.

Note:

• Not designed to break down polyols (e.g., sorbitol, mannitol), which may still cause symptoms in sensitive individuals.

• Should not be taken alongside prebiotic supplements such as MegaPre™.

• Intended for short-term use as part of a gut restoration protocol.

Overview

PEA + Meriva Curcumin by Enzyme Science is a specialized formula designed to support the nervous system, joint comfort and recovery from physical stress. The formula combines ultra-micronized palmitoylethanolamide (PEA) with Meriva® curcumin phytosome, a highly bioavailable form of curcumin.

PEA is a naturally occurring fatty acid amide produced by the body that helps regulate inflammatory signaling and supports nerve comfort. Curcumin from turmeric provides additional antioxidant and cellular support. Together these ingredients help support healthy response to occasional physical stress, overexertion and muscle soreness.

The formula uses ultra-micronized PEA, which improves absorption and bioavailability compared to standard forms. Meriva® curcumin phytosome is a patented curcumin-phospholipid complex designed to significantly improve curcumin absorption. :contentReference[oaicite:0]{index=0}

Key Benefits

• Supports healthy nervous system function
• Helps support recovery after physical stress or overexertion
• Supports joint comfort and mobility
• Helps maintain healthy inflammatory response
• Supports muscle and tissue recovery
• Highly bioavailable forms of PEA and curcumin

Supplement Facts

Serving Size: 2 Capsules

Servings Per Container: 30/60

† Daily Value not established.

Other Ingredients: Vegetarian capsule (HPMC, water), rice concentrate.

Free From: Casein, crustaceans, eggs, fish, gluten, milk, nuts, sesame, shellfish, soy and wheat. No artificial colors, fillers or flavors.

How It Works

Palmitoylethanolamide (PEA) is a naturally occurring lipid compound produced by the body. It interacts with immune and nervous system pathways involved in inflammatory signaling and nerve function.

Ultra-micronization reduces particle size, improving absorption and allowing more efficient delivery of PEA to tissues.

Meriva® Curcumin Phytosome is a curcumin-phospholipid complex that significantly improves curcumin absorption compared with standard curcumin extracts. This allows better utilization of curcumin’s antioxidant and cellular support properties.

Suggested Use

Take 2 capsules twice daily with or without food, or as recommended by a healthcare practitioner.

FAQ

What is PEA?
Palmitoylethanolamide (PEA) is a naturally occurring lipid produced by the body that plays a role in regulating inflammatory and nerve signaling pathways.

What makes ultra-micronized PEA different?
Ultra-micronization reduces particle size, improving solubility and absorption compared to standard PEA forms.

What is Meriva® curcumin?
Meriva® is a patented curcumin phytosome complex that binds curcumin to phosphatidylcholine, increasing absorption and bioavailability.

Can this supplement support joint and muscle comfort?
The combination of PEA and curcumin is commonly used to support joint comfort, nerve health and recovery from physical stress.

Is this product vegetarian?
Yes. The capsules are made from plant-based materials and the formula does not contain common allergens.

Storage

Store in a cool, dry place with the container tightly closed.

Multi-enzyme formula for extensive digestive support

Benefits and Features

• Supports the breakdown of fat, fiber, protein & carbs to speed up digestion^†
• Helps reduces occasional gas, bloating, and indigestion^†
• Safe for routine daily use or as needed

Ther-Biotic® Vital-Zymes™ Complete supports healthy digestion of all major nutrient types (proteins, fats, carbohydrates). Perfect for those with occasional food sensitivities or indigestion, and delivers a full complement of high activity enzymes.^†

Detail Overview

Our best-selling multi-enzyme formulation offers an unusually comprehensive range of plant/ microbial-based enzymes, together with lysozyme, that work in concert to support normal enzyme activities such as digestion of foods and intestinal repair and maintenance mechanisms.^† The broad-spectrum combination of enzymes in Ther-Biotic® Vital-Zymes™ Complete supports the breakdown, absorption, and utilization of macronutrients from a wide spectrum of foods, including proteins and protein peptides, complex carbohydrates, disaccharides and sugars, lipids/fats, and vegetable fibers.^† As such, Ther-Biotic® Vital-Zymes™ Complete is an important dietary adjunct for individuals who seek to improve nutrient uptake, and for those with occasional indigestion.^† It can also be used for individuals who wish to support a balanced microbiota and healthy inflammation metabolism.^†

Attributes of Ther-Biotic® Vital-Zymes™ Complete

• Contains highly purified enzymes to meet the needs of food-sensitive individuals
• Contains no porcine or other animal-derived enzymes
• Avoids fruit-derived enzymes (bromelain, papain, and kiwi) for improved tolerance by sensitive individuals
• Active across a broad range of pH conditions (pH of 2 to 10) for benefit throughout the entire intestinal tract 
• Supplies a broad spectrum of disaccharidases (lactase, maltase, sucrase/invertase, pullulanase, and isomaltase) to assist in cleaving of sugars that may be fermented by organisms that shift the balance of microbiota†
• Assists protein breakdown, but avoids excessive amounts of proteases that may irritate GI tissues^†
• Dipeptidyl peptidase IV (DPP-IV) activity supports optimal cleaving of casein and gluten and their exorphin peptides (casomorphin and gluteomorphin)^†
• Supplies Serratia peptidase enzyme to support sensitive GI tissues from irritation and lysozyme for its unique lysing action on bacterial and yeast cell walls and broad immune support^†

Supports Healthy Blood Flow

Benefits and Features

Supports healthy blood clotting, circulation, and platelet function by helping to maintain your body's ability to break down unwanted blood clots in vessels.^† Free of vitamin K.

Detail Overview

Nattokinase is a proteolytic enzyme whose principle effect is fibrinolysis or degradation of fibrin, a fibrillar protein that when linked together forms the mesh essential for blood clot formation.^† Nattokinase also upregulates the body’s natural mechanism that guards against excess fibrin formation.† Nattokinase may support healthy blood clotting, circulation, and platelet function by helping to maintain optimum function of the body’s normal fibrinolytic processes.^† Produced from fermentation of non-GMO soybean isolates by Bacillus subtilis natto. Standardized to fibrin activity units and free of vitamin K.

SUPPLEMENT FACTS

Chewable multi-enzyme formula to support and enhance digestion^†

Benefits and Features

• Supports the breakdown of fat, fiber, protein & carbs to speed up digestion^†
• Reduces occasional gas, bloating, and indigestion^†
• Safe for routine daily use or as needed

Provides a comprehensive array of digestive enzymes to support healthy digestion and ease occasional indigestion.^†

Detail Overview

Ther-Biotic® Vital-Zymes™ (Chewables) offer a convenient choice when a chewable version of our popular Ther-Biotic® Vital-Zymes™ Complete enzyme formula is desired. Formulated using the same enzymes contained in Ther-Biotic® Vital-Zymes™ Complete with the exclusion of lysozyme, Ther-Biotic® Vital-Zymes™ (Chewables) is a good choice for administering enzymes to children or adults who may prefer a chewable tablet. This broad-spectrum enzyme formulation has moderate amounts of enzymes compared to Ther-Biotic® Vital-Zymes™ Complete to allow it to be comfortably chewed for routine daily use or as needed. Ther-Biotic® Vital-Zymes™ (Chewables) can assist in the breakdown of a wide range of proteins, peptides, fats, complex carbohydrates, sugars, and fibers.^† Serratia peptidase, a unique endopeptidase enzyme, helps protect sensitive GI tissue from irritation that can affect tissue health and intestinal comfort.^† Enzymes with DPP-IV activity and a full range of disaccharidases are included.^†

Suggested Use

Adults: 2 tablets at the beginning of each meal or as directed by a healthcare professional. Children: As directed by a healthcare professional.