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Jarrow Formulas® Methyl B-12 & Methyl Folate plus Pyridoxal-5-Phosphate (P5P) combines the biologically active coenzyme forms of vitamin B12, B9 and B6 that support cellular energy metabolism and neurotransmitter synthesis.* This combination supports the recycling of homocysteine to methionine to support cardiovascular health.
- Provides Methyl B-12 plus Methyl Folate and Pyridoxal 5-Phosphate in a Convenient Chewable Tablet Form
- Cellular Energy Metabolism and Cardiovascular Health*
- 1000 mcg Methyl B-12 and 400 mcg Methyl Folate per serving
- Lemon and Other Natural Flavors Chewable Tablet
- Methylcobalamin (Methyl B-12) and Methyl Folate are biologically active forms of vitamin B12 and B9*
- Methyl Folate is unlike synthetic folic acid that may mask vitamin B12 deficiency*
- Pyridoxal 5-Phosphate (P-5-P) Is the Coenzyme Form of Vitamin B6*
- Vegan, Non-GMO, Gluten Free
Suggested use
Adults take 1 chewable tablet once a day or as directed by your qualified healthcare professional.
WARNING: Consult a healthcare professional before using this product if you are pregnant, nursing, under the age of 18, are taking medication (especially antiepileptic and chemotherapy) or have a medical condition; if adverse reactions occur, discontinue use.
| Supplement facts | ||
| Serving Size: 1 Tablet | ||
| Amount Per Serving | %DV | |
| Vitamin B6 (as Pyridoxal-5-Phosphate) | 1.5 mg | 88% |
| Folate (400 mcg as (6S)-5-MTHF [from (6S)-5-Methyltetrahydrofolate Glucosamine Salt]) | 680 mcg DFE‡ | 170% |
| Vitamin B12 (as Methylcobalamin) | 1,000 mcg | 41,667% |
| ‡Dietary Folate Equivalents. | ||
Other ingredients
Xylitol, microcrystalline cellulose, stearic acid (vegetable source), natural flavor, citric acid, magnesium stearate (vegetable source), silicon dioxide and rebaudioside A (stevia extract).
No wheat, gluten, soybeans, dairy, egg, fish/shellfish, peanuts/tree nuts or sesame.
Keep out of the reach of children.
P-5-P – Active Vitamin B6 for Amino Acid and Neurotransmitter Support
P-5-P provides pyridoxal 5’-phosphate (P-5-P), the active coenzyme form of vitamin B6, to support amino acid metabolism, neurotransmitter synthesis, liver function, and overall nervous system health.
This well-absorbed, bioactive form of B6 bypasses the need for conversion in the liver, making it ideal for individuals with compromised B6 metabolism.
Key Benefits*
-
Supports amino acid metabolism
-
Promotes neurotransmitter production (e.g., serotonin, dopamine, GABA)
-
Aids in liver function and red blood cell formation
-
Helps maintain a healthy nervous system
-
Provides B6 in its active, ready-to-use form
Supplement Facts (per capsule)
-
Vitamin B6 (as pyridoxal 5’-phosphate): 30 mg (1765% DV)
-
Other ingredients: Microcrystalline cellulose, vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine
Suggested Use
Take 1 capsule daily with food or as directed by your healthcare professional.
Highlights
✔ Active coenzyme form of B6
✔ Hypoallergenic and well-tolerated
✔ Gluten-free, dairy-free, soy-free
✔ Suitable for vegetarians
| Serving Size 1 Capsule | ||
| Amount Per Capsule | % Daily Value | |
|---|---|---|
| Vitamin B6 ( as pyridoxal 5'- phosphate) | 30 mg | 1,765% |
Other Ingredients:
Microcrystalline cellulose, vegetarian capsule (hydroxypropyl methylcellulose, water), and L-leucine.
Suggested Use
Adults: 1 capsule daily with food or as directed by a healthcare professional. Children: As directed by a healthcare professional.
Allergy Statement
Made without common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, soybeans, and sesame. Non-GMO, Vegan/ No synthetic colors, flavors, or preservatives.
Caution
Consult with your physician if you are pregnant or nursing, or have any medical condition, or taking prescription drugs, or under the age of 18 years. KEEP OUT OF REACH OF CHILDREN.
Methyl Folate ((6S)-5-methyltetrahydrofolate or (6S)-5-MTHF) is a highly biologically active form of folate.* Due to the body’s limited ability to transform synthetic folic acid into the active form of folate, supplementation with 5-MTHF is highly preferable.
- Biologically Active Folate (Methyl Folate [5-MTHF])
- Quatrefolic®: 4th Generation Development in Folate Delivery
- Increased Stability & Bioavailability
Suggested use
Adults take 1 capsule once a day with or without food or as directed by your qualified healthcare professional.
WARNING: Consult a healthcare professional before using this product if you are pregnant, nursing, under the age of 18, are taking medication (especially antiepileptic and chemotherapy) or have a medical condition; if adverse reactions occur, discontinue use.
Keep out of the reach of children.
| Supplement facts | ||
| Serving Size: 1 Capsule | ||
| Amount Per Serving | % DV | |
| Folate (1,000 mcg as (6S)-5-MTHF [from (6S)-5-Methyltetrahydrofolate Glucosamine Salt]) |
1,700 mcg DFE‡ | 425% |
| ‡Dietary Folate Equivalents. | ||
Other ingredients
Microcrystalline cellulose, capsule (hydroxypropylmethylcellulose, water) and magnesium stearate (vegetable source).
No wheat, gluten, soybeans, dairy, egg, fish/shellfish, peanuts/tree nuts or sesame.
95% polyphenol content
Provides epigallocatechin gallate (EGCG), an important polyphenol in green tea that promotes fat oxidation and calorie-burning.†
Contains significantly higher amounts of epigallocatechin gallate (EGCG), the most active catechin (polyphenol), compared to most green tea extracts. Catechin polyphenols and other compounds in green tea act in synergy to promote fat oxidation and thermogenesis.†
| Serving Size 1 Capsule | ||
| Amount Per Capsule | % Daily Value | |
|---|---|---|
| Green Tea Extract (Camellia sinensis)(leaf)(standardized to 95% polyphenols, 50% epigallocatechin 3-gallate [250 mg EGCG]) |
500 mg | * |
| * Daily value not established | ||
Other Ingredients:
Vegetarian capsule (hydroxypropyl methylcellulose, water), microcrystalline cellulose, ascorbyl palmitate, and silicon dioxide.
Suggested Use
Adults: 1 capsule daily with food or as directed by a healthcare professional.
Allergy Statement
Free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, soybeans, and yeast. Contains no artificial colors, flavors, or preservatives.
Caution
Do not exceed the recommended amount. Not for use by persons under 18 years of age. Take with food. If you are pregnant, nursing, have a medical condition, or taking prescription drugs, consult your physician before using this product. Do not take this product if you have liver disease or elevated liver enzymes. If you experience nausea, vomiting, abdominal pain, yellowing of the skin/eyes, dark urine, sweating, unusual tiredness and/or loss of appetite, stop using this product and contact your physician. Each capsule contains up to approximately 5 mg caffeine. KEEP OUT OF REACH OF CHILDREN.
Overview
TMG (Trimethylglycine) is a targeted methylation support formula designed to help maintain healthy homocysteine metabolism, liver function, and cellular resilience. Also known as betaine, TMG serves as both a methyl donor and a cellular osmolyte, supporting important metabolic and protective processes throughout the body.
This formula provides 750 mg of trimethylglycine per capsule in a simple, focused single-ingredient format for daily methylation and metabolic support.
Key Benefits
- Supports healthy methylation pathways
- Helps maintain normal homocysteine metabolism
- Supports liver and kidney cellular health
- Acts as a methyl donor for methionine production
- Functions as a cellular osmolyte for stress resilience
- Provides 750 mg of trimethylglycine per capsule
Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 100
| Ingredient | Amount Per Serving | % Daily Value |
|---|---|---|
| Trimethylglycine | 750 mg | Daily Value not established |
Other Ingredients: Hydroxypropyl methylcellulose, microcrystalline cellulose, L-leucine.
How It Works
Trimethylglycine (TMG), also known as betaine, is a methyl donor that helps convert homocysteine into methionine through methylation pathways. This supports healthy homocysteine balance and contributes to normal metabolic processes involved in cardiovascular, liver, and cellular health.
TMG also functions as a cellular osmolyte, helping cells maintain fluid balance and structural stability under stress. This dual role makes it especially useful for supporting methylation efficiency and resilience in stress-prone tissues such as the liver and kidneys.
Suggested Use
As a dietary supplement, take 1 capsule twice daily before meals, or as directed by a healthcare practitioner.
FAQ
What is TMG?
TMG stands for trimethylglycine, also known as betaine. It is a compound that supports methylation and healthy homocysteine metabolism.
What does this supplement support?
It is designed to support methylation, liver health, homocysteine metabolism, and cellular stress resilience.
How much TMG is in each capsule?
Each capsule provides 750 mg of trimethylglycine.
When should it be taken?
The suggested use is 1 capsule twice daily before meals, or as directed by a healthcare practitioner.
Is this a single-ingredient formula?
Yes. The active ingredient is trimethylglycine (TMG), making it a focused single-ingredient methylation support formula.
Storage
Store in a cool, dry place, tightly capped, away from light. Keep out of the reach of children. Use only if safety seal is intact. Variations in product color may occur.
Methyl Folate ((6S)-5-methyltetrahydrofolate or (6S)-5-MTHF) is a highly biologically active form of folate.* Due to the body’s limited ability to convert synthetic folic acid into the active form of folate, supplementation with (6S)-5-MTHF is preferable.
- A Highly Bioactive Form Of Folate
- Quatrefolic®
- Increased Stability & Bioavailability
- Extra Strength, 400mcg of Folate Per Serving
Suggested use
Adults take 1 capsule once a day with or without food or as directed by your qualified healthcare professional.
WARNING: Consult a healthcare professional before using this product if you are pregnant, nursing, under the age of 18, are taking medication (especially antiepileptic and chemotherapy) or have a medical condition; if adverse reactions occur, discontinue use.
| Supplement facts | ||
| Serving Size: 1 Capsule | ||
| Amount Per Serving | %DV | |
| Folate (400 mcg as (6S)-5-MTHF [(6S)-5-Methyltetrahydrofolate Glucosamine Salt) | 680 mcg DFE‡ | 170% |
| ‡Dietary Folate Equivalents. | ||
Other ingredients
Microcrystalline cellulose capsule (hydroxypropylmethylcellulose, water) and magnesium stearate (vegetable source).
No wheat, gluten, soybeans, dairy, egg, fish/shellfish, peanuts/tree nuts or sesame.
Keep out of the reach of children.
Vitamin B6 with Magnesium
Benefits and Features
The active form of vitamin B6 plus magnesium to support the health and function of your brain, nervous system, blood vessels, skin, and eyes.†
Detail Overview
Pyridoxal 5’-phosphate (P-5-P) is the active coenzyme form of vitamin B6 that is directly utilized by the body. P-5-P plays an important role in amino acid metabolism, neurotransmitter production, and a variety of other metabolic reactions such as the metabolism of carbohydrates, fats, and proteins.† Magnesium is included to assist vitamin B6 metabolism. In addition, these 2 nutrients are frequently found as cofactors for the same enzymes.
SUPPLEMENT FACTS
| Serving Size 1 Capsule | ||
| Amount Per Capsule | % Daily Value | |
|---|---|---|
| Vitamin B6 (as pyridoxal 5’-phosphate) | 30 mg | 1,765% |
| Magnesium (as TRAACS® magnesium bisglycinate chelate, magnesium oxide‡) | 100 mg | 24% |
Other Ingredients:
Vegetarian capsule (hydroxypropyl methylcellulose, water) and ascorbyl palmitate.
‡Albion® and TRAACS® are registered trademarks of Albion® Laboratories, Inc.
Suggested Use
Adults: 1 capsule daily with food or as directed by a healthcare professional. Children: As directed by a healthcare professional.
Allergy Statement
Made without common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, soybeans, and sesame. Non-GMO, Vegan, No synthetic colors or flavors.
Caution
Consult your physician If you are pregnant or nursing, or have a medical condition, or taking prescription drugs, or under the age of 18 years. KEEP OUT OF REACH OF CHILDREN.
Jarrow Formulas® Methyl B-12 & Methyl Folate plus Pyridoxal-5-Phosphate (P-5-P) combines biologically active forms of vitamin B12, B9, and B6 that support cellular energy metabolism and neurotransmitter synthesis.* This combination supports the recycling of homocysteine to methionine to support cardiovascular health.
- Provides Methyl B-12 plus Methyl Folate and Pyridoxal 5-Phosphate in a Convenient Chewable Tablet Form
- Cellular Energy Metabolism and Cardiovascular Health*
- 5000 mcg Methyl B12 and 800 mcg Methyl Folate per serving
- Methylcobalamin (Methyl B12) and Methyl Folate are biologically active forms of vitamin B12 and B9
- Methyl Folate is unlike synthetic folic acid that may mask vitamin B12 deficiency
- Pyridoxal 5-Phosphate (P-5-P) Is the Coenzyme Form of Vitamin B6
Suggested use
Adults take 1 chewable tablet once a day or as directed by your qualified healthcare professional.
WARNING: Consult a healthcare professional before using this product if you are pregnant, nursing, under the age of 18, are taking medication (especially antiepileptic and chemotherapy) or have a medical condition; if adverse reactions occur, discontinue use.
Keep out of the reach of children.
| Supplement facts | ||
| Serving Size: 1 Tablet | ||
| Servings Per Container: 60 | ||
| Amount Per Serving | %DV | |
| Vitamin B₆ (as Pyridoxal 5-Phosphate) | 2.5 mg | 147% |
| Folate (800 mcg as 6S)-5MTHF-Methyltetrahydrofolate Glucosamine Salt) | 1,360 mcg DFE‡ | 340% |
| Vitamin B12 (as Methylcobalamin) | 5,000 mcg | 208,330% |
| ‡Dietary Folate Equivalents. | ||
Other ingredients
Xylitol, microcrystalline cellulose, stearic acid (vegetable source), natural flavor, citric acid, rebaudioside A (stevia) extract and magnesium stearate (vegetable source).
No wheat, gluten, soybeans, dairy, egg, fish/shellfish, peanuts/tree nuts or sesame.
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