Enzymes

Enzyme Science

Complete Digestion capsules Enzyme Science

From $13.50

Enzyme Science

Acid Calm™ 90 сapsules Enzyme Science

$28.99

Overview

Acid Calm by Enzyme Science is a digestive support formula designed to help soothe occasional heartburn and indigestion while supporting healthy digestion and stomach lining integrity.

The formula combines digestive enzymes, PepZinGI® zinc carnosine, and marshmallow root to support both digestion and gastrointestinal comfort. This combination helps maintain the natural protective lining of the stomach while assisting the body in breaking down food efficiently.

PepZinGI® zinc carnosine has been studied for its ability to support gastrointestinal mucosal health and help maintain stomach lining integrity. Marshmallow root provides soothing mucilage compounds that help calm irritated digestive tissues. :contentReference[oaicite:0]{index=0}

Key Benefits

Supports relief of occasional heartburn and indigestion
Helps protect and support the stomach lining
Supports healthy digestion and nutrient absorption
Contains soothing marshmallow root for GI comfort
Includes Thera-blend® digestive enzymes
Protease-free enzyme formula for gentle digestive support

Supplement Facts

Serving Size: 1 Capsule

Servings Per Container: 90

Amount Per Serving	% Daily Value
Zinc (from 10 mg PepZinGI® Zinc Carnosine)	2 mg (18%)
Marshmallow Root (Althaea officinalis)	233 mg †
Acid Calm Enzyme Blend	215 mg †
Cellulase Thera-blend®	600 CU
Lipase Thera-blend®	200 FIP
Amylase Thera-blend®	3,000 DU

† Daily Value not established.

Other Ingredients: Vegetarian capsule (HPMC, water).

Free From: Casein, crustaceans, eggs, fish, gluten, milk, nuts, sesame, shellfish, soy and wheat. No artificial colors, fillers or flavors.

How It Works

Zinc Carnosine (PepZinGI®) helps support and protect the stomach’s mucosal lining while maintaining gastrointestinal integrity.

Marshmallow Root contains natural mucilage compounds that help soothe irritated digestive membranes and support gastrointestinal comfort.

Thera-blend® enzymes support the breakdown of food components, helping reduce digestive stress and promoting efficient nutrient absorption.

Suggested Use

Take 1 capsule at the end of a meal to calm digestive discomfort. The product may also be taken any time digestive discomfort begins, or as recommended by a healthcare practitioner.

FAQ

What is PepZinGI®?
PepZinGI® is a patented zinc-carnosine complex designed to support the stomach lining and gastrointestinal health.

Can Acid Calm help with occasional heartburn?
Yes. The formula is designed to support digestive comfort and help soothe occasional heartburn and indigestion.

Why are digestive enzymes included?
Digestive enzymes help break down food efficiently, which may reduce digestive stress that contributes to occasional digestive discomfort.

Is this product vegetarian?
Yes. The capsules are plant-based and the formula does not contain common allergens.

Storage

Store in a cool, dry place with the container tightly closed.

Enzyme Science

Telomere Pro™ 30 capsules Enzyme Science

$43.99

Integrative Therapeutics

Similase® GFCF 120 capsules Integrative Therapeutics

$35.25

RELIEVES OCCASIONAL INDIGESTION, GAS, AND BLOATING

Digestion of gluten and casein can be particularly difficult for some individuals. Similase GFCF contains enzymes to support comprehensive digestion, while also providing dipeptidyl peptidase IV (DPP IV) activity for the digestion of proline-containing dipeptides from gluten and casein.* Similase GFCF supports a gluten-free, casein-free lifestyle and helps relieve occasional indigestion, gas, and bloating.

DIRECTIONS

Similase® GFCF Directions and/or Dosage Adults take 2 capsules with each meal or as recommended by a healthcare professional.

Warning If you are pregnant, nursing, have diabetes or if you are taking prescription drugs, consult a healthcare professional before use. While Similase® GFCF will reduce the level of reactive gliadin and gluten proteins in a meal, it is advised that celiac disease sufferers continue with their normal gluten exclusion diet as even small amounts of gliadin can cause adverse reactions in the most sensitized individuals. Keep out of reach of children. Safety sealed with inner seal. Do not use if seal is broken or missing. Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.

FAQS

Q: What are the sources of the enzymes used in Similase® GFCF?

A: The vegetarian enzymes used in Similase® GFCF are produced through the fermentation of fungal organisms, including Aspergillus, Rhizopus, and Saccharomyces. Some of the vegetarian enzyme products contain maltase, which is derived from malt barley. If a product contains maltase, it is not gluten-free.

Q: What do the abbreviations for enzyme activity units (e.g., USP, HUT, etc.) stand for?

A: There are many scientific systems used for measuring enzyme activity. The most common enzyme measurement systems are Food Chemical Codex (FCC), United States Pharmacoepia (USP), and Federal Internationale Pharmaceutique (FIP). Each different enzyme measurement system has an enzyme assay method with its own units of measurements. For example, one of the enzyme measurements from protease is HUT (Hemoglobin Unit Tyrosine). Here are some common enzyme activity abbreviations:HUT = hemoglobin unit tyrosine PC = Bacterial Protease Unit DU = apha-amylase dextrinizing unit LU = lipase units PU = phytase units ALU = acid lactase unit CU = cellulase units INVU = inverted unitLacU = lactase activity unit

Supplement Facts
Serving Size: 2 capsules
Servings Per Container: 60

Amount Per Serving	%DV
Microbial Enzymes	621 mg
- DPP IV Protease Blend (Protease I, II, III, IV, V) FCC (pH 4.7)	134,660 HUT
- FCC (pH 7.0)	22,660 PC
- USP (pH 7.5)	12,557 USP
- Amylase FCC (pH 4.6)	16,370 DP°
- FCC (pH 4.8)	16,370 DU
- USP (pH 6.8)	10,913 USP
- Lactase I, II FCC (pH 4.5)	642 ALU
- Lipase I, II FCC (pH 7.0)	888 FIP
- Cellulase I, II FCC (pH 4.5)	141 CU
- Sucrase (Invertase) FCC (pH 4.5)	181 SU
- Phytase FCC (pH 5.5)	0.68 FTU

%DV: Daily Value (DV) not established
†Percent daily value is based on a 2000 calorie diet

Other Ingredients:
Plant-derived capsule (hypromellose), cellulose, inulin (from chicory root), calcium laurate, silica.

Similase® GFCF Does Not Contain:

Dairy, Colors, Artificial Flavors, Preservatives

Klair Labs

THER-BIOTIC® SIBB-Zymes™ 180 capsules Klaire Labs / SFI Health

$61.99

Brush Border Enzymes

Benefits and Features

Digestive enzymes to support the end steps of carbohydrate and protein digestion.^†

Detail Overview

Critical enzymes for the final steps of carbohydrate and protein digestion. Supplementation may be helpful if genetic and other factors have disrupted your small intestine's brush border, causing low activity of these brush border enzymes.^†

A variety of genetic and acquired factors can disrupt the small intestine brush border, which may result in low activity of brush border enzymes. THER-BIOTIC® SIBB-Zymes™ supplies a blend of enzymes normally found in the small intestinal brush border that are critical for the final steps of carbohydrate and protein digestion. Disaccharide enzymes (lactase, maltase, and sucrase) are supplied together with glucoamylase to assist optimal cleaving of sugars and carbohydrates that if left undigested may affect absorption and microbial fermentation, contributing to a shift in the balance of yeast and bacteria.^†

THER-BIOTIC® SIBB-Zymes™ includes an active enzyme blend of peptidase and protease with dipeptidyl peptidase IV (DPP-IV) activity. Peptidase and protease enzymes help break down plant and animal proteins, including casein (milk/dairy products), gluten (wheat, rye, oats, barley, and other grains), and soy.^† Peptidase enzymes that express DPP-IV activity are especially effective in breaking down proline-rich exorphin (opiate-acting) peptides derived from incompletely digested casein, gluten, and soy that may influence central nervous system function in some individuals. THER-BIOTIC® SIBB-Zymes™ can help break down dietary disaccharides and oligosaccharides, including lactose.^†

SUPPLEMENT FACTS

Amount Per 2 Capsules		% Daily Value
Serving Size 2 Capsules
Enzyme Blend (microbially derived)		612 mg*
Glucoamylase		120 AGUΔ*
Protease/Peptidase Complex with endopeptidase, exopeptidase, and DPP-IV activity		121,660 HUTΔ*
Sucrase (invertase)		1,000 SUΔ*
Lactase		3,600 ALUΔ*
Maltase		600 DPΔ*

Other Ingredients:

Vegetarian capsule (hydroxypropyl methylcellulose, water) and microcrystalline cellulose, and silicon dioxide.

References: undefined

∆Units are those used in the Food Chemicals Codex (FCC).

Suggested Use

Adults: 2 capsules at the beginning of each meal or as directed by a healthcare professional. Children: As directed by a healthcare professional.

Allergy Statement

Made without common allergens: milk/casein, eggs, fish, shellfish, tree nuts, and peanuts, soybeans, and sesame. Vegan, No synthetic colors, flavors, or preservatives.

Caution

If you are pregnant, nursing, have a medical condition, or taking prescription drugs, consult your physician before using this product. KEEP OUT OF REACH OF CHILDREN.

FAQS

What is SIBB-Zymes™?

SIBB-Zymes™ is a Small Intestine Brush Border (SIBB) enzyme formulation that supports the final brush border stages of digestion and absorption.

This formula contains enzymes normally found in the brush border that are critical for the final steps of carbohydrate and protein digestion. Disaccharide enzymes (lactase, maltase, and sucrase) are supplied together with glucoamylase to assist optimal cleaving of sugars and carbohydrates.

SIBB-Zymes™ also includes a high-activity enzyme blend of peptidase and protease enzymes with dipeptidyl peptidase IV (DPP-IV) activity. Peptidase and protease enzymes help break down plant and animal proteins, including casein (milk/dairy products), gluten (wheat, rye, oats, barley, and other grains), and soy.^† Peptidase enzymes that express DPP-IV activity are needed to break down proline-rich exorphin (opiate-acting) peptides derived from incompletely digested casein, gluten, and soy that may affect central nervous system function in some individuals.

Why support the small intestine brush border?

Genetic, immunologic, bacterial, inflammatory, and environmental factors can influence the function and integrity of the brush border and its enzymes.

Brush border enzyme function may be affected by congenital or developmental factors. Lactase deficiency is the most common (39%) while other enzyme deficiencies such as sucrase (9%) are less common.

Cigarette smoking can also compromise function of the brush border.

How do I know if the brush border is not functioning optimally?

Occasional abdominal pain, bloating, gas, indigestion, or loose stool may indicate the need for support of the small intestinal brush border.

Why were these specific enzymes included in SIBB-Zymes™ and what do they do?

Glucoamylase is an enzyme that facilitates the digestion of sugars and long chain carbohydrates found in foods like corn, wheat, rice, and potatoes that, if left undigested, may lead to incomplete absorption with microbial fermentation, altering the balance of yeast and bacteria in the gut.^†

Lactase is an essential enzyme for the complete digestion of lactose, a carbohydrate in milk. Approximately 65% of the human population has a reduced ability to digest lactose after infancy. Lactase has been included to support the digestion of lactose and dairy products.

Maltase is a carbohydrate-digesting enzyme that is part of the final step of the digestion of carbohydrates and a naturally occurring sugar (maltose) that is found in malt, grains, and many processed foods.

Sucrase (invertase) digests what is commonly known as table sugar, as well as the components of complex carbohydrates. In humans, sucrase is linked with isomaltase. Unfortunately, most plant-derived sucrase supplements do not contain isomaltase which makes the inclusion isomaltase activity an important component of this formula.

The protease/peptidase complex contains peptidases and proteases that help break down difficult-to-digest proteins both from the ends of protein chains and from within. The complex also provides enzymes with dipeptidyl peptidase IV, or DPP-IV, activity, essential for the complete breakdown of proline-rich proteins and the inactivation of exorphins.

What makes SIBB-Zymes™ unique?

Optimal support should include disaccharadiases with overlapping glucoamylase and isomaltase activity, as well as DPP-IV activity, to ensure complete digestion of gluten, casein, and soy. Unlike many sucrase containing formulas, SIBB-Zymes™ provides isomaltase activity from Glucoamylase to support the digestion of carbohydrates. In addition, the enzymes provided in this formula are active across a broad pH range, unlike animal-derived digestive enzymes which are active only in a narrow pH range.

Who should take SIBB-Zymes™?

Children or adults wishing to assist more complete breakdown and absorption of disaccharides like lactose, trisaccharides, oligosaccharides, casein, gluten, and soy by supporting healthy brush border enzyme function may benefit from the use of SIBB-Zymes™. SIBB-Zymes™ may be especially suitable for individuals following a carbohydrate-restricted diet such as the FODMAPS, GAPS, and SCD diets.

What is the difference between SIBB-Zymes™ and Vital-Zymes™ Complete?

SIBB-Zymes™ specifically supports small intestine brush border (SIBB) enzyme function and supports more complete breakdown and absorption of casein, gluten, disaccharides, and oligosaccharides. SIBB-Zymes™ contains higher levels of these brush border enzymes to support the final stages of digestion compared to the broad spectrum activity of Vital-Zymes™ Complete.

SIBB-Zymes™ may be used as a stand-alone formula to support activity of these brush border enzymes; especially if this is the primary digestive need. It may also be used as a complement to Vital-Zymes™ Complete when higher digestive support of brush border enzyme activity/function is indicated to help maintain efficient digestive function and enhance nutrient absorption.

How many SIBB-Zymes™ should be taken?

The suggested use is 2 capsules taken at the beginning of a meal (or based on the amount food being consumed). There has been no upper limit established for enzyme supplementation. Large doses may be ingested without toxicity or adverse effects. People with active peptic ulcer or gastritis should not take SIBB-Zymes™ or other protease-containing supplements.

Are the enzymes vegetarian?

The enzymes are microbial-derived enzymes (carbohydrases, peptidases, and proteases from non-pathogenic species of Aspergillus) contained in a base of cellulose, and encapsulated in Kosher-certified vegetarian capsules. There are no porcine or bovine ingredients, nor are there any fruit-derived enzymes for optimal tolerance in phenol-sensitive individuals.

Can the capsules be opened?

Capsules can be opened and mixed with a small amount of food or beverage as long as it is not hot. When mixing capsule contents in foods, avoid contact with eyes and inhalation of powder as the enzymes may cause some irritation to mucus membranes. Foods treated in this manner should be consumed immediately.

Are there any contraindications or side effects?

Unlike certain vitamins, minerals, and herbs, there is no known upper limit (or threshold) to the amount of supplemental enzymes that can be consumed. No side effects have been reported with oral use of these enzymes. However, those with known allergies to Aspergillus should avoid using this product unless otherwise directed by their healthcare professional. In addition, persons with gastritis, active ulcers, gastroesophageal reflux disorder (GERD), or known damage to the gastrointestinal mucosa should not use this product unless otherwise directed by their healthcare professional. People with diabetes should use the products only under supervision of a medical professional.

Can pregnant and lactating women use the product?

Pregnant or nursing women should consult with a healthcare professional before using supplemental enzymes.

How will I know when SIBB-Zymes™ is working?

Improvements in digestion and gastrointestinal function may be seen immediately upon taking an enzyme supplement or may take several days to several weeks to become noticeable.

Premier Research Labs

Inflammacidin™ 90 capsules Premier Research Labs

$61.99

Enzyme Science

Intolerance Complex™ capsules Enzyme Science

From $22.99

Overview

Intolerance Complex™ by Enzyme Science is a comprehensive digestive enzyme formula designed to support the breakdown of foods associated with common food intolerances. The formula contains high-potency enzymes that help digest gluten, dairy proteins, lactose, phenols and complex carbohydrates.

Digestive enzymes help break food down into smaller nutrients that the body can absorb and utilize for energy, growth and cellular repair. When enzyme production is insufficient, digestion may slow down and lead to occasional bloating, gas and abdominal discomfort. Intolerance Complex™ helps support efficient digestion and nutrient absorption.

Key Benefits

Supports digestion of gluten, dairy and phenols
Helps reduce occasional bloating, gas and indigestion
Supports digestion of proteins, carbohydrates, fats and fiber
High-potency digestive enzyme formula
Supports common food intolerances
Thera-blend® enzyme technology for activity across a wide pH range

Supplement Facts

Serving Size: 2 Capsules

Servings Per Container: 15/45

Amount Per Serving	Activity	% Daily Value
DPP-IV	2,000 DPPU	†
Xylanase	30,000 XU	†
Protease Thera-blend®	140,000 HUT	†
ATP Pro® (ATP, Magnesium Citrate, Phytase, CoQ10)	155 mg	†
Amylase Thera-blend®	14,000 DU	†
Alpha Galactosidase	1,200 GalU	†
Glucoamylase	40 AGU	†
Lactase	3,000 ALU	†
Pectinase	50 Endo-PGU	†
Maltase	200 DP	†
Lipase Thera-blend®	800 FIP	†
Cellulase Thera-blend®	400 CU	†
Invertase	150 SU	†
Hemicellulase	50 HCU	†

† Daily Value not established.

Other Ingredients: Vegetarian capsule (HPMC, water).

Free From: Casein, crustaceans, eggs, fish, gluten, milk, nuts, sesame, shellfish, soy and wheat. No artificial colors, fillers or flavors.

Suggested Use

Take 1–2 capsules per meal with the first bite of food, or as recommended by a healthcare practitioner.

FAQ

What does Intolerance Complex help digest?
This formula supports digestion of gluten, dairy proteins, lactose, phenols, complex carbohydrates and other macronutrients.

When should I take digestive enzymes?
Digestive enzymes are most effective when taken with the first bite of food.

Can digestive enzymes help with occasional bloating?
When food is properly broken down, fermentation in the gut may be reduced, which can help decrease occasional bloating and gas.

Is this product vegetarian?
Yes, the capsules are vegetarian and the formula does not contain common food allergens.

Can I take more than one capsule?
Yes, 1–2 capsules per meal are recommended depending on the meal and individual needs.

Storage

Store in a cool, dry place with the container tightly closed.

Enzyme Science

Apple Cider Vinegar 60 capsules Enzyme Science

$29.99

Enzymes

About Enzymes