About Life Extension
Life Extension is a privately owned vitamin and supplement company founded in 1980 and headquartered in Fort Lauderdale, Florida.
The brand offers a broad range of science-based supplements, vitamins, minerals, antioxidants, probiotics, specialty formulas, and wellness products across many health categories.
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298 products
Homocysteine Resist by Life Extension is a vegetarian capsule supplement featuring a targeted selection of B vitamins and folate. The Shopify package contains 60 capsules.
This formula combines riboflavin (vitamin B2), vitamin B6, vitamin B12, and folate as L-5-methyltetrahydrofolate (L-5-MTHF) to support already-healthy homocysteine levels, heart health, brain health, and cellular energy production.
Key Benefits
- Helps maintain homocysteine levels already within the normal range
- Supports a healthy vascular system
- Supports neurotransmitter synthesis for cognitive health
- Supports cellular energy production with vitamin B2
- Provides selected forms of vitamins B6, B12, and folate
Ingredient Breakdown
| Ingredient or Feature | Role in the Formula |
|---|---|
| Riboflavin (vitamin B2) | Included as part of the B-vitamin formula supporting homocysteine balance and cellular energy production. |
| Vitamin B6 as pyridoxyl 5’-phosphate | Supports neurotransmitter synthesis, amino acid metabolism, and lipid metabolism. |
| Folate as L-5-methyltetrahydrofolate calcium salt | Helps maintain homocysteine levels within the normal range and supports neurotransmitter synthesis for cognitive health. |
| Vitamin B12 as methylcobalamin | Included in the targeted B-vitamin combination for homocysteine support. |
How It Works
Homocysteine Resist brings together selected B vitamins and folate in one formula. Folate and vitamin B12 help maintain homocysteine levels within the normal range, while folate and vitamin B6 support neurotransmitter synthesis. Vitamin B2 supports the body’s energy production, complementing the formula’s focus on heart, brain, and cellular support.
Suggested Use
Take one (1) capsule daily with food, or as recommended by a healthcare practitioner.
Caution
- KEEP OUT OF REACH OF CHILDREN
- DO NOT EXCEED RECOMMENDED DOSE
- Do not purchase if outer seal is broken or damaged.
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Quality & Certifications
- Non-GMO
Frequently Asked Questions
What is Homocysteine Resist?
Homocysteine Resist is a Life Extension B-vitamin supplement formulated to support already-healthy homocysteine levels, heart health, and brain health.
Which ingredients are included?
The formula includes riboflavin (vitamin B2), vitamin B6 as pyridoxyl 5’-phosphate, folate as L-5-methyltetrahydrofolate calcium salt, and vitamin B12 as methylcobalamin.
How should I take it?
Take one (1) capsule daily with food, or as recommended by a healthcare practitioner.
What package is available?
The Shopify package contains 60 capsules.
Is the formula non-GMO?
Yes. Homocysteine Resist is identified as Non-GMO.
Life Extension Discomfort Relief (Berry Flavor) 60 is a convenient berry-flavored chewable tablet featuring 600 mg of PEA (palmitoylethanolamide). PEA is a compound naturally produced by your body.
Designed to support comfort during occasional minor discomfort, this chewable supplement provides a convenient way to take PEA without swallowing the tablet whole. The product is available as 60 chewables.
Key Benefits
- Supports comfort during occasional minor discomfort
- Provides PEA (palmitoylethanolamide) in a convenient chewable format
- Berry flavored for convenient use
Ingredient Breakdown
| Ingredient or Feature | Role in the Formula |
|---|---|
| Palmitoylethanolamide (PEA) | The featured compound in the formula, included to support comfort during occasional minor discomfort. |
| Berry flavor | Provides the product's berry flavor. |
| Chewable tablet | Offers a convenient format that should be chewed rather than swallowed whole. |
How It Works
Discomfort Relief provides PEA (palmitoylethanolamide), a compound naturally produced by your body, in a chewable tablet. The formula is designed to support comfort during occasional minor discomfort while offering a convenient berry-flavored format.
Who Is It For?
Discomfort Relief is intended for those seeking support for occasional minor discomfort in a convenient chewable supplement.
Suggested Use
- Chew one (1) tablet once or twice daily, or as recommended by a healthcare practitioner.
- Do not swallow tablets whole.
Quality & Certifications
- Non-GMO
Frequently Asked Questions
What is Discomfort Relief?
Discomfort Relief is a berry-flavored chewable supplement featuring PEA (palmitoylethanolamide).
How much PEA does each serving provide?
Each serving provides 600 mg of PEA (palmitoylethanolamide).
How should Discomfort Relief be used?
Chew one (1) tablet once or twice daily, or as recommended by a healthcare practitioner. Do not swallow tablets whole.
What flavor is Discomfort Relief?
Discomfort Relief has a berry flavor.
How many chewables are included?
The package contains 60 chewables.
Caution
- KEEP OUT OF REACH OF CHILDREN
- DO NOT EXCEED RECOMMENDED DOSE
- Do not purchase if outer seal is broken or damaged.
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
ComfortMAX™ 60 AM/PM tablets from Life Extension combine palmitoylethanolamide (PEA) with honokiol from Magnolia bark in a dual-action formula designed to support nerve comfort.
The AM/PM format provides separate morning and bedtime tablets for support throughout the day and night.
Key Benefits
- Supports nerve cell health with palmitoylethanolamide (PEA)
- Honokiol encourages healthy levels of calming neurotransmitters in the brain
- Supports comfort through complementary AM and PM formulas
- Designed for morning and nighttime use
Ingredient Breakdown
| Ingredient or Feature | Role in the Formula |
|---|---|
| Palmitoylethanolamide (PEA) | Supports nerve cell health and helps inhibit inflammatory factors. |
| Honokiol from Magnolia bark | Encourages healthy levels of calming neurotransmitters in the brain. |
| AM/PM tablet format | Provides separate morning and bedtime formulas for day-and-night comfort support. |
How It Works
ComfortMAX™ combines PEA and honokiol to support nerve comfort through complementary actions. PEA supports nerve cell health by helping inhibit inflammatory factors, while honokiol encourages healthy levels of calming neurotransmitters in the brain.
Suggested Use
Take one (1) AM tablet in the morning and one (1) PM tablet before bed, or as recommended by a healthcare practitioner.
Caution
The blue PM tablet may cause mild sedation in some people. Take at bedtime.
Warnings
- KEEP OUT OF REACH OF CHILDREN
- DO NOT EXCEED RECOMMENDED DOSE
- Do not purchase if outer seal is broken or damaged.
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Quality & Certifications
Non-GMO
Frequently Asked Questions
What is ComfortMAX™?
ComfortMAX™ is an AM/PM tablet formula from Life Extension designed to support nerve comfort.
Which ingredients are included?
The formula includes palmitoylethanolamide (PEA) and honokiol from Magnolia bark.
How should ComfortMAX™ be used?
Take one (1) AM tablet in the morning and one (1) PM tablet before bed, or as recommended by a healthcare practitioner.
When should the PM tablet be taken?
Take the blue PM tablet at bedtime.
What dietary attribute does the product have?
ComfortMAX™ is Non-GMO.
Adding L-Carnitine to your supplement regimen provides a host of potential health benefits associated with aging. It starts with supporting mitochondria, which power every cell in your body.
What Is L-Carnitine?
Mitochondria, the powerhouses found within human cells, produce the energy that vital tissues need to keep us vibrant and healthy. Healthy levels of carnitine support optimum functioning of mitochondria and your body’s energy production.
Maintaining optimal mitochondrial function is important for many aspects of healthy aging.
L-Carnitine Benefits
- Helps maintain cellular metabolic activity
- Supports healthy concentration of nitric oxide, which helps support already-healthy blood pressure
- Supports the brain's natural defenses against age-related memory & cognitive decline
- Helps maintain healthy body composition
Protecting Cellular Energy
L-carnitine is an amino acid produced in your body. It plays an important role in moving fatty acids into the mitochondria of your cells. This is important, since as we age, there is a steady decline in cellular energy. The primary reason is that our mitochondria aren’t functioning properly. Healthy levels of carnitine support optimum functioning of mitochondria.
Mitochondria, the powerhouses found within human cells, produce the energy that vital tissues need to keep us vibrant and healthy. Healthy levels of carnitine support optimum functioning of mitochondria.1 The problem is that as we age, levels of carnitine decline in all our tissues, reducing cellular energy production and metabolic activity.
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- KEEP OUT OF REACH OF CHILDREN
- DO NOT EXCEED RECOMMENDED DOSE
- Do not purchase if outer seal is broken or damaged.
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Life Extension Pyridoxal 5-Phosphate is a capsule supplement featuring the metabolically active form of vitamin B6, pyridoxal 5’-phosphate. This product is available as 60 capsules and is designed to support the body’s normal coenzyme-dependent chemical reactions.
Pyridoxal 5’-phosphate may also help support healthy nerve, eye, cardiovascular, and kidney function while supporting the body’s defenses against glycation reactions involving lipids and proteins.
Key Benefits
- Provides pyridoxal 5’-phosphate, the metabolically active form of vitamin B6.
- Supports normal coenzyme activity in chemical reactions.
- Helps support healthy nerve, eye, cardiovascular, and kidney function.
- Supports the protection of lipids and proteins against glycation reactions.
- Non-GMO formula.
Ingredient Breakdown
| Ingredient or Feature | Role in the Formula |
|---|---|
| Pyridoxal 5’-phosphate | The metabolically active form of vitamin B6, included to support coenzyme-dependent chemical reactions and healthy body function. |
How It Works
Pyridoxal 5’-phosphate functions as a coenzyme in chemical reactions. The source also describes it as supporting the protection of living lipids and proteins against glycation reactions, helping provide nutritional support for healthy nerve, eye, cardiovascular, and kidney function.
Suggested Use
Take one (1) capsule daily with food, or as recommended by a healthcare practitioner.
Caution
- KEEP OUT OF REACH OF CHILDREN
- DO NOT EXCEED RECOMMENDED DOSE
- Do not purchase if outer seal is broken or damaged.
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Quality & Certifications
Non-GMO.
Frequently Asked Questions
What is this supplement designed to support?
It is designed to support coenzyme-dependent chemical reactions and healthy nerve, eye, cardiovascular, and kidney function.
What form of vitamin B6 does it provide?
It provides pyridoxal 5’-phosphate, described as the metabolically active form of vitamin B6.
How should it be taken?
Take one (1) capsule daily with food, or as recommended by a healthcare practitioner.
How many capsules are in the package?
The package contains 60 capsules.
Life Extension PQQ 20 mg capsules provide PQQ (pyrroloquinoline quinone) in a vegetarian capsule format. This formula is designed to support mitochondrial biogenesis, cellular energy production, antioxidant protection, and healthy mitochondrial DNA.
Each package contains 30 capsules. PQQ supports the growth of new cellular mitochondria and helps maintain youthful cellular energy levels, with additional support for heart and cognitive health.
Key Benefits
- Supports mitochondrial biogenesis and the growth of new cellular mitochondria
- Helps maintain healthy cellular energy production
- Provides cellular antioxidant support
- Helps support healthy mitochondrial DNA
- Supports heart and cognitive health
Ingredient Breakdown
| Ingredient or Feature | Role in the Formula |
|---|---|
| PQQ disodium salt (pyrroloquinoline quinone) | Supports mitochondrial biogenesis, cellular energy production, antioxidant protection, and healthy mitochondrial DNA. |
| Microcrystalline cellulose | Other ingredient in the formula. |
| Vegetable cellulose | Vegetarian capsule material. |
| Silica | Other ingredient in the formula. |
| Stearic acid | Other ingredient in the formula. |
How It Works
PQQ is designed to support mitochondrial biogenesis, the process associated with maintaining cellular mitochondria. By supporting mitochondria, PQQ helps promote healthy cellular energy production and provides antioxidant support for mitochondrial DNA.
Suggested Use
Take one (1) capsule daily, or as recommended by a healthcare practitioner.
Serving Size: 1 Vegetarian Capsule
Quality & Certifications
- Non-GMO
- Vegetarian
Caution
- KEEP OUT OF REACH OF CHILDREN
- DO NOT EXCEED RECOMMENDED DOSE
- Do not purchase if outer seal is broken or damaged.
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Frequently Asked Questions
What is Life Extension PQQ designed to support?
It is designed to support mitochondrial biogenesis, cellular energy production, antioxidant protection, and healthy mitochondrial DNA.
What is the active ingredient?
The active ingredient is PQQ disodium salt, also known as pyrroloquinoline quinone.
How should this supplement be used?
Take one (1) capsule daily, or as recommended by a healthcare practitioner.
Is this product vegetarian?
Yes. It is identified as vegetarian and uses a vegetable cellulose capsule.
Healthy aging, oxidative stress, heart & brain, absorbable formula
Aging like fine wine. This formula promotes healthy aging via cardiovascular health support, oxidative stress defense and more, and features an ultra-absorbable resveratrol as well as quercetin.
What Is Optimized Resveratrol Elite™?
Resveratrol is an anti-aging supplement that’s good for your heart, mind, and cellular health. But traditional resveratrol has low bioavailability. This formula contains trans-resveratrol in a hydrogel coating to improve bioavailability up to a whopping 10x! That is combined with a high-bioavailability form of quercetin—a phytonutrient that’s good for your heart and immune system. This advanced formula allows your body to make the most of these super-nutrients' health benefits.
Resveratrol is a healthy aging nutrient. Quercetin promotes heart and immune health. This supplement gives you a healthy dose of both.
Optimized Resveratrol Elite™ Benefits
- Contains healthy aging nutrient trans-resveratrol
- Provides up to 10x better bioavailability*
- Helps maintain already-healthy blood pressure
- Protects against oxidative stress
- Supports brain health
- Contains bioavailable quercetin
*Than unformulated resveratrol
Better resveratrol—no red wine required
You’ve probably heard about research that red wine is good for you. Science has found that the grapes red wine is made from contain resveratrol, a polyphenol that promotes a wide range of health and healthy aging mechanisms. But resveratrol has low bioavailability. We’ve solved this problem by combining trans-resveratrol (from Japanese knotweed) with a hydrogel coating of galactomannan fibers from fenugreek seeds. Doing this protects resveratrol once you’ve ingested it. This increases resveratrol’s bioavailability up to 10x, delivering much more of this healthy aging nutrient to your cells.
Resveratrol is a well-known healthy aging nutrient. Our Resveratrol Elite™ formulas contain trans-resveratrol, the form associated with beneficial biological effects. Resveratrol also promotes healthy insulin sensitivity, supports a healthy inflammatory response and has been shown to promote healthy endothelial function for a healthy cardiovascular system.
A more bioavailable resveratrol
We’ve combined resveratrol with galactomannan fibers from fenugreek seeds. This makes our Resveratrol Elite™ formulas up to 10 times more bioavailable. This means that the trans-resveratrol in this product reaches higher levels in your bloodstream and circulates longer than traditional, unformulated resveratrol.
Resveratrol and heart health
One way that resveratrol can promote heart health is by helping to shield your cells from oxidative stress. Resveratrol also promotes endothelial health and function—an essential component of living a long, healthy life.
Resveratrol and brain health
At the same time, resveratrol has shown an ability to help the brain and cognition: In a randomized controlled trial, it encouraged healthy neurological function as well as brain blood flow. These are additional ways in which resveratrol can bolster even more essential aspects of healthy aging.
Augmenting resveratrol with quercetin
Our formula also delivers quercetin, a phytonutrient that complements resveratrol. In a randomized clinical study, researchers compared the formulated Bio-Quercetin to unformulated quercetin. They found that the quercetin formulated with fenugreek fibers led to serum levels of total quercetin up to 62 times higher than unformulated quercetin, and 18 times higher levels of free (unconjugated) quercetin.
Quercetin promotes both cardiovascular and endothelial health and helps maintain healthy blood pressure already within the normal range. Quercetin is also a potent inhibitor of oxidative stress and helps promote a healthy inflammatory response.
Quercetin promotes a healthy immune response in the face of seasonal immune challenges. In a randomized clinical trial, quercetin encouraged a healthy immune response in physically fit older adults.
Non-GMO |
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- KEEP OUT OF REACH OF CHILDREN
- DO NOT EXCEED RECOMMENDED DOSE
- Do not purchase if outer seal is broken or damaged.
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Cholesterol & blood pressure health support, antioxidant support
This formula promotes cardiovascular health: specifically already-healthy cholesterol and blood pressure levels. It also offers powerful antioxidant support.
Optimized Quercetin is a cardiovascular and antioxidant support formula. It contains 250 mg of quercetin as well as 30 mg of vitamin C. This formula also has 220 mg of an optimized food blend sourced from onion, bitter orange and apple, along with an extract of camu-camu berry. Each bottle of Optimized Quercetin contains enough for a 1–2-month supply, depending on dosage. It is non-GMO and gluten-free.
Looking to maintain healthy cholesterol and blood pressure levels? Optimized Quercetin should be at the heart of your supplement routine.
Optimized Quercetin Benefits
- Encourages overall cardiovascular health
- Supports already healthy blood pressure levels
- Helps maintain cholesterol levels already in normal range
- Novel nutrient blend helps the body manage oxidative stress
What is quercetin?
Quercetin is a phytonutrient found in plants including apples, onions and citrus fruits. Quercetin encourages healthy nitric oxide levels, which helps maintain already healthy blood pressure, and supports healthy cholesterol levels already within normal range. It also has strong antioxidant properties.
Why Should I Supplement With Optimized Quercetin?
- Supports already healthy blood pressure levels
- Helps maintain cholesterol levels already in normal range
- This formula combines quercetin and vitamin C for added antioxidant support
Quercetin is an antioxidant that supports healthy nitric oxide levels. Quercetin helps maintain cardiovascular health: it encourages already healthy blood pressure levels, and when taken regularly over time, it can help support cholesterol levels already within normal range.
Our Optimized Quercetin blend also contains vitamin C, an optimized food blend from onions, bitter orange, and apple, and camu-camu (Myrciaria dubia) berry extract. Camu-camu is a tropical fruit rich in vitamin C. These nutrients were included as sources of quercetin, vitamin C, and other phytonutrients for added antioxidant support.
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| Dosage and Use | |||||||||||||||||
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- KEEP OUT OF REACH OF CHILDREN
- DO NOT EXCEED RECOMMENDED DOSE
- Do not purchase if outer seal is broken or damaged.
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
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