Microbiome Labs

MegaGuard™ is a novel digestive aid that combines licorice polyphenols, cleansing artichoke leaf extract, and soothing ginger to promote normal digestion, regulate stomach acid, maintain healthy H. pylori levels, and reduce occasional digestive discomforts such as gas and bloating. With the power of these herbs combined, MegaGuard™️ provides unique and comprehensive digestive support, bowel regularity, and gastric balance.*
Suggested Use: Ages 8+: Take one capsule with lunch and dinner, or as directed by your healthcare practitioner.

Serving Size: 1 Capsule 

Amount Per Serving
Artichoke leaf extract ... 320mg
Gutgard® licorice flavonoids ... 75mg
Ginger root extract ... 30mg
(20% gingerols)

Other Ingredients: Cellulose, vegetable capsule (water and cellulose).
If you are pregnant or nursing; taking any medication; have a medical condition, consult your doctor before using this product.  Keep out of reach of children.  Do not use if safety seal is broken or missing.

MegaMycoBalance™ – Targeted Yeast & Fungal Balance Support, 180 Softgels

Microbiome Labs

Clinically Formulated Support for Yeast Balance in the Gut and Beyond

MegaMycoBalance™ is a specialized formula designed to support healthy yeast and fungal balance throughout the body, with a particular focus on the digestive tract. It features two key active ingredients — undecylenic acid and bee propolis — known for their antifungal activity and ability to maintain microbial equilibrium.

By helping to manage yeast levels in the gut, MegaMycoBalance™ can also support balanced microflora in the vaginal, oral, and skin microbiomes, all of which are influenced by gut health. This makes it an ideal part of antifungal protocols, gut restoration plans, or maintenance routines after antibiotic or high-sugar exposure.

Key Benefits

• Helps maintain healthy yeast and fungal levels in the GI tract

• Disrupts fungal biofilms and inhibits yeast-to-hyphae transformation

• Supports microbial balance and immune function in the gut

• Promotes healthy vaginal flora by modulating gut-based yeast activity

• May aid in managing chronic or recurrent fungal overgrowth symptoms

• Gradual dose escalation for increased tolerance and flexibility

Active Ingredient Science

Undecylenic Acid
A powerful antifungal fatty acid derived from castor bean oil. It inhibits yeast cell growth and biofilm formation, and may help prevent Candida albicans from converting into its aggressive filament (hyphal) form that penetrates the intestinal wall.

Bee Propolis (70% extract)
A natural resin used by bees to protect hives from microbial threats. Rich in bioflavonoids like pinocembrin, galangin, and pinobanksin, bee propolis has been shown to help maintain fungal balance by inhibiting the growth of common yeast species.

Together, these ingredients deliver a dual-action antifungal effect that targets both active yeast and protective biofilms — a critical part of managing difficult or persistent fungal imbalances.

Supplement Facts

Serving Size: 6 softgels
Servings Per Container: 30

Other Ingredients:
Olive oil, bovine gelatin, glycerin, purified water, beeswax, sunflower lecithin.
Contains: bee products.

Suggested Use

Ages 8 and up:

• Start with 1 softgel daily for 5 days

• Gradually increase by 1 softgel every few days

• Maximum dosage: 6 softgels daily, or as recommended by your healthcare practitioner

Children under 8: Use only under medical supervision.
Best taken with or without meals. Drink plenty of water throughout the day.

Frequently Asked Questions (FAQ)

Q: What symptoms may indicate a need for yeast balance support?
A: Bloating, brain fog, skin irritation, recurrent vaginal yeast issues, sugar cravings, or white coating on the tongue can all suggest fungal imbalance.

Q: Can I combine MegaMycoBalance™ with probiotics or gut protocols?
A: Yes. It works well alongside MegaSporeBiotic™, Mega IgG2000™, or MegaMucosa™ as part of a total gut restoration or Candida protocol.

Q: Does this product kill all yeast?
A: No. It supports balance, helping reduce overgrowth while preserving the beneficial functions of commensal yeasts.

Q: How long can I use it?
A: Typical protocols last 4–8 weeks, but your practitioner may recommend longer use depending on your needs.

FODMATE™ – Targeted Enzyme Support for FODMAP Digestion, 120 Capsules

Microbiome Labs

Digestive Support for High-FODMAP Foods

FODMATE™ is an advanced digestive enzyme formula designed to support the breakdown of high-FODMAP foods and ease occasional digestive discomfort. It helps address symptoms such as bloating, abdominal discomfort, gas, and occasional constipation often associated with fermentable carbohydrates. FODMATE™ is ideal for short-term use in conjunction with a low-FODMAP diet or as targeted support when consuming high-FODMAP foods.

Key Benefits

• Supports digestion of fermentable carbohydrates (FODMAPs)

• Helps reduce occasional bloating, gas, and abdominal discomfort

• Enables continued intake of nutrient-rich, plant-based foods

• Supports adherence to restrictive diets without excessive food elimination

• May ease the transition away from low-FODMAP diets during microbiome restoration

Supplement Facts

Serving Size: 2 capsules
Servings Per Container: 60

Other Ingredients:
Cellulose, vegetarian capsule (cellulose and water)

Suggested Use

Adults and children age 8 and older: Take 2 capsules with a meal, 2–3 times per day or as directed by your healthcare practitioner.

Children under 8: Consult a healthcare practitioner before use.

Note:

• Not designed to break down polyols (e.g., sorbitol, mannitol), which may still cause symptoms in sensitive individuals.

• Should not be taken alongside prebiotic supplements such as MegaPre™.

• Intended for short-term use as part of a gut restoration protocol.

MegaSporeBiotic™ Gummies for Kids – Spore-Based Gut Support in a Fruity Gummy, 30 Count

Microbiome Labs

Delicious Daily Probiotic Support for Children Ages 4+

MegaSporeBiotic™ Gummies for Kids deliver clinically studied spore-forming probiotics in a fun, flavorful, and easy-to-chew format. Designed specifically for children 4 years and older, these gummies help support gut microbial diversity, maintain a healthy gut barrier, and promote balanced immune function — all in a tasty mixed berry gummy that kids love.

Each gummy contains a proprietary blend of four Bacillus strains, including the flagship Bacillus indicus HU36™ and Bacillus subtilis HU58™, shown to survive digestion, colonize the gut, and support microbiome health naturally.

Key Benefits

• Supports microbial diversity and gut balance

• Helps maintain a healthy gut barrier and digestive integrity

• Promotes immune regulation and healthy inflammatory response

• Naturally flavored with blueberry, strawberry, and blackberry

• 100% spore-based probiotics – no refrigeration needed

• Dairy-free, soy-free, non-GMO, and free of artificial colors

• Kid-friendly delivery format — no pills or powders

Science Behind the Strains

Each gummy contains 2 Billion CFU from a clinically tested probiotic blend:

• Bacillus indicus HU36™ – Supports production of antioxidant carotenoids (astaxanthin, lycopene, lutein), quinols, and vitamins at the absorption site

• Bacillus clausii SC109 – Acid-resistant; supports respiratory and gut health, and maintains microbial balance

• Bacillus subtilis HU58™ – Promotes gut motility, gut lining integrity, vitamin production (B group, K2), and immune balance

• Bacillus coagulans SC208 – Supports digestion and metabolism, may help with occasional constipation and diarrhea

Unlike conventional probiotics, these Bacillus spores survive digestion, arrive in the intestines alive, and activate where they’re needed most — promoting a stable and functional microbiome.

Supplement Facts

Serving Size: 1 gummy
Servings Per Container: 30
Probiotic Blend: 2 Billion CFU

Proprietary Spore-Based Probiotic Blend:

• Bacillus indicus HU36™

• Bacillus clausii (SC109)

• Bacillus subtilis HU58™

• Bacillus coagulans (SC208)

Other Ingredients:
Tapioca syrup, sugar, purified water, dextrose, pectin, natural flavors (blueberry, strawberry, blackberry), citric acid, MCT oil (from palm oil), natural fruit & vegetable color concentrates, sodium citrate, carnauba wax.

Suggested Use

Ages 4+: Take 1 gummy per day, or as directed by your healthcare practitioner.
Chew thoroughly before swallowing.

No refrigeration required. Store in a cool, dry place.

Frequently Asked Questions (FAQ)

Q: Are these suitable for children under 4?
A: No. MegaSporeBiotic™ Gummies for Kids are formulated for ages 4 and up. For younger children, consult your pediatrician.

Q: Can adults take these?
A: Adults may benefit from a higher dose. Microbiome Labs also offers MegaSporeBiotic™ Gummies for Adults, with 2x the CFU per serving.

Q: Do the gummies contain sugar?
A: Yes, 1 gram of added sugar per gummy, from tapioca syrup and dextrose. No artificial sweeteners.

Q: Are they shelf-stable?
A: Yes. Spore-forming probiotics do not require refrigeration and are highly stable at room temperature.

PyloGuard™ – Targeted H. pylori Detox Support with Patented Postbiotic, 30 Capsules

Microbiome Labs

Gut Detox Innovation Powered by Inactivated Lactobacillus reuteri DSM17648

PyloGuard™ is a groundbreaking postbiotic supplement that supports the body’s natural elimination pathways and helps reduce the microbial load of Helicobacter pylori (H. pylori) in the stomach and upper digestive tract. Its key ingredient, Lactobacillus reuteri DSM17648, is a patented strain shown in clinical studies to bind, aggregate, and promote the excretion of H. pylori without disrupting the broader gut microbiome.

Unlike traditional treatments that may cause side effects or bacterial resistance, PyloGuard™ offers a gentle, microbiome-compatible approach to digestive health.

Key Benefits

• Supports natural reduction of H. pylori colonization**

• Promotes healthy microbial balance in the stomach and upper GI tract

• Aids the body’s natural detox and elimination processes

• Shelf-stable and resistant to gastric acid

• Contains only inactivated (postbiotic) cells – no live bacteria

• Can be paired with MegaSporeBiotic™ and MegaGuard™ for enhanced support

• Safe for long-term daily use

• Does not disrupt beneficial commensal flora

What Is H. pylori and Why Support Detox?

H. pylori is a spiral-shaped, gram-negative bacterium that colonizes the gastric mucosa. Up to 50% of the world’s population may carry it. It’s difficult to eliminate because:

• It adheres tightly to stomach lining

• It produces ammonia to neutralize stomach acid

• It thrives in low-acid conditions and may resist antibiotics

PyloGuard™ addresses these challenges by binding H. pylori in the gut using inactivated L. reuteri cells, facilitating their removal naturally — without harsh chemicals or gut-disrupting agents.

Clinically Studied Postbiotic

In a proof-of-concept, randomized placebo-controlled trial, Lactobacillus reuteri DSM17648 was shown to:

• Significantly reduce H. pylori load in healthy but infected individuals

• Promote selective bacterial-to-bacterial aggregation, leading to physical removal via the digestive tract

• Work synergistically with Bacillus-based probiotics (like MegaSporeBiotic™)

Note: PyloGuard™ does not kill H. pylori; it binds to it, reducing its presence over time while preserving microbiome balance.

Supplement Facts

Serving Size: 1 capsule
Servings Per Container: 30

MegaPre™ – Precision Prebiotic for Microbiome Support, 180 Capsules

Microbiome Labs

Targeted Prebiotic Support for Keystone Gut Bacteria

MegaPre™ is a next-generation Precision Prebiotic™ supplement designed to support the growth of specific, health-promoting bacteria in the gut without stimulating the overgrowth of unwanted species. Unlike generic prebiotics that may feed both good and harmful microbes, MegaPre™ uses clinically studied oligosaccharides and organic kiwifruit powder to selectively nourish keystone species — the core beneficial bacteria critical for microbiome health and immune function.

This capsule form offers convenient, tasteless dosing for individuals who prefer not to mix powders and still want the full benefit of targeted prebiotic support.

Key Benefits

• Supports microbial diversity in the gut

• Selectively feeds keystone bacterial strains: Akkermansia muciniphila, Faecalibacterium prausnitzii, and Bifidobacteria

• Reinforces the positive microbial shifts created by MegaSporeBiotic™

• Supports short-chain fatty acid (SCFA) production, including butyrate

• Promotes healthy intestinal barrier integrity and immune modulation

• Convenient capsule format — no mixing required

Science Behind MegaPre™

Keystone species like Akkermansia muciniphila and Faecalibacterium prausnitzii are foundational for gut health — but are often depleted due to antibiotics, processed foods, and environmental toxins. These species regulate inflammation, produce beneficial metabolites (like butyrate), and maintain the structural integrity of the gut lining.

MegaPre™ feeds these species with a proprietary blend of:

• Galactooligosaccharides (Bimuno®) – selectively fermented by bifidobacteria and associated with improved immune response and digestive health

• Xylooligosaccharides (PreticX®) – shown to increase SCFA production and encourage growth of beneficial gut flora

• Kiwifruit powder (ACTAZIN® & Livaux®) – a natural source of fiber and polyphenols that supports bowel regularity, mucosal health, and microbial diversity

Together, these ingredients deliver a precise, controlled prebiotic effect, making MegaPre™ an ideal companion to probiotic therapy or gut restoration programs.

Supplement Facts

Serving Size: 6 capsules
Servings Per Container: 30

Other Ingredients:
Vegetable capsule (cellulose and water), cellulose, magnesium stearate, silicon dioxide.
Contains: milk (from lactose-derived ingredients). Dairy-free options available upon request.

Suggested Use

Ages 4 and up:

• Start with 3 capsules daily (with or without food) for the first week

• Increase to 6 capsules daily as tolerated or as directed by your healthcare practitioner

Children under 4: Use only under medical supervision.

Frequently Asked Questions (FAQ)

Q: What makes MegaPre™ a “Precision Prebiotic”?
A: Unlike broad-spectrum prebiotics, MegaPre™ targets only beneficial species, avoiding overgrowth of non-beneficial bacteria.

Q: Can I use this with probiotics like MegaSporeBiotic™?
A: Yes. In fact, MegaPre™ is designed to reinforce and sustain the microbial changes induced by MegaSporeBiotic™.

Q: What results can I expect?
A: Improved gut comfort, better stool consistency, enhanced immunity, and increased energy — typically noticeable within 2–4 weeks of consistent use.

Q: Why capsules instead of powder?
A: The capsule format is ideal for those sensitive to flavors or who prefer precise, mess-free dosing — especially when traveling or on the go.

SereneSkin™ – Gut-Skin Axis Probiotic for Clear, Radiant Skin, 60 Capsules

Microbiome Labs

Clinically Formulated Probiotic Skincare from Within

SereneSkin™ is a first-of-its-kind, ingestible probiotic skincare supplement that supports the gut-skin axis, helping to promote healthy, hydrated, and visibly clearer skin from the inside out. This formula contains a clinically studied blend of four spore-based Bacillus probiotic strains, alongside plant-based antioxidants and vitamin K2, to reduce occasional blemishes, balance oil and moisture levels, and enhance microbial harmony on both the gut and skin.

This daily two-capsule supplement is designed for those who want to address skin issues at the root cause — through gut health.

Key Benefits

• Supports clear and radiant skin from within

• Helps reduce occasional non-cystic acne and blemishes

• Promotes balanced oil and moisture levels in skin

• Supports gut microbial diversity and barrier function

• Maintains healthy skin microbiome balance

• Clinically studied ingredients targeting the gut-skin axis

• Shelf-stable, vegan, allergen-free

How It Works

The gut and skin are both rich in microbial ecosystems that communicate via the immune and nervous systems — this is called the gut-skin axis. When the gut is imbalanced, the skin often shows signs like breakouts, dryness, or irritation.

SereneSkin™ uses spore-forming Bacillus strains to support gut health and reduce intestinal permeability (“leaky gut”), which in turn helps balance the skin's microbial environment and reduce inflammatory signals that lead to acne or dryness.

Active Ingredients

Proprietary Bacillus Probiotic Blend (6.5 Billion CFU)

• Bacillus indicus HU36™ – Produces antioxidant carotenoids (lycopene, beta-carotene) that support skin tone and defense

• Bacillus subtilis HU58™ – Balances the gut microbiome and promotes vitamin K2 production

• Bacillus clausii SC109 – Supports immune and respiratory function, microbial harmony

• Bacillus coagulans SC208 – Produces lactic acid; supports digestion and gut pH balance

Citrus Bioflavonoids (MicrobiomeX®)

• From Citrus sinensis and Citrus paradisi

• Provide natural antioxidant and anti-inflammatory activity in both gut and skin

Golden Tomato Carotenoids (Lumenato™)

• Natural source of phytoene and phytofluene, plant pigments that protect skin from oxidative stress and UV damage

Vitamin K2 (Menaquinone-7)

• Supports skin elasticity, vascular health, and optimal calcium metabolism

Supplement Facts

Serving Size: 2 capsules
Servings Per Container: 30