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Melatonin releases from the pineal gland, reaching its peak at night to help maintain healthy cell health throughout the body.82 Secretion of melatonin declines significantly with age, as the pineal gland becomes calcified.83 Jet lag, shift work, and poor vision can disrupt melatonin cycles.84-86
Melatonin keeps our circadian cycle in tune.87, 88 Not only does this hormone work to maintain cell health, it appears to regulate a system of self-repair and regeneration.89-94 As melatonin diminishes with age, our biological functions are impaired.95, 96 Melatonin also has strong antioxidant properties. It directly scavenges both hydroxyl and peroxyl free radicals, and it does so more effectively than most other antioxidants. It also greatly potentiates the efficiency of other endogenous and exogenous antioxidants.97 Melatonin is especially important for protecting cellular DNA against peroxynitrite damage by inhibiting peroxynitrite free radical reactions.98 Some research has found that melatonin increases the speed of falling asleep and adds to the quality of sleep in about 60% of people who use it.99-102
References available upon request.
Take one (1) capsule 30 to 60 minutes before bedtime, or as recommended by a healthcare practitioner. Melatonin is naturally secreted from the pineal gland at night, and should be taken at night for optimal results.
Serving Size: 1 capsule
Amount Per Serving
Melatonin ... 3mg
Other ingredients: rice flour, gelatin.
Non-GMO
Caution
Consult your healthcare provider before taking this product if you are being treated for a medical condition (especially autoimmune or depressive disorders). Use caution if combining with alcohol. This product is not intended for children, pregnant or lactating women, or women trying to become pregnant. Do not attempt to drive or operate heavy machinery after taking this product.
Warnings
KEEP OUT OF REACH OF CHILDREN
DO NOT EXCEED RECOMMENDED DOSE
Do not purchase if outer seal is broken or damaged
HELPS PROMOTE A RESTFUL, RELAXED STATE
L-Theanine is an amino acid that helps promote a restful, relaxed state without diminishing daytime alertness.
HOW IT WORKS
Human studies have found that supplemental L-theanine promotes the generation of alpha brain waves, suggesting a state of relaxation.* Controlled clinical trials have shown that L-theanine can support a healthy stress response.
DIRECTIONS
L-Theanine Directions and/or Dosage Adults take 2 capsules one to two times daily.
Warning If you are pregnant, nursing, or taking any medications, consult a healthcare professional before use. Keep out of reach of children. Safety sealed with inner seal. Do not use if seal is broken or missing. Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.
FAQS
Q: Does L-theanine affect serotonin levels?
A: The effect of L-theanine on brain levels of serotonin in humans is still unclear. Animal studies completed to date have provided conflicting data. Until more research is completed, we recommend that persons taking antidepressant medications consult their healthcare practitioner before using L-theanine.
| Ingredients | Amount Per Serving | % Daily Value |
|---|---|---|
| L-Theanine | 200mg | ** |
Serving Size
2 capsules
Other Ingredients
- Cellulose
- Plant-derived capsule (hypromellose)
- Magnesium stearate
L-Theanine Does Not Contain
- Wheat
- Gluten
- Corn
- Soy
- Dairy
- Colors
- Flavors
Zahler's Junior Melatonin provides 1 mg of sleep-enhancing Melatonin for children.
- Supports quality sleep
- Provides 1 mg Melatonin per tablet
- Delicious-tasting grape flavor
Zahler's Junior Melatonin provides 1 mg of sleep-regulating melatonin to support restful and quality sleep. Melatonin is a natural seep aid that the brain produces in response to darkness. Supplementing with additional Melatonin is a quick and easy sleep booster.
Suggested use
Children ages 4+ take 1 chewable tablet at bedtime or as directed by a healthcare practitioner.
You may need additional supplements to support a healthy diet; consult your nutritionist for a formula that is right for you.
Warnings
Keep out of reach of children. Do not use if safety seal is damaged or missing. If pregnant, nursing or on medication, consult with your healthcare practitioner.
Store tightly closed in a cool, dry place.
| Supplement facts | ||
| Serving Size: 1 Tablet | ||
| Servings Per Container: 120 | ||
| Amount Per Serving | %Daily Value for Adults and Children ≥ 4 Years | |
| Melatonin | 1 mg | * |
| * Daily Value not established. | ||
Warnings
Keep out of reach of children. Do not use if safety seal is damaged or missing. If pregnant, nursing or on medication, consult with your healthcare practitioner.
Store tightly closed in a cool, dry place.
Jarrow Formulas® 5-HTP 5-Hydroxytryptophan) is an extract of Griffonia simplicifolia seeds from coastal West Africa. Purity is assured by HPLC. 5-HTP is the direct metabolic precursor to serotonin and is important for the production of melatonin, a hormone secreted by the pineal gland that aids biorhythm regulation.
- Help Support A Balanced Mood
- 5-HTP Is A Precursor To Serotonin
- 50 mg 5-HTP Per Serving
- Vegan, Non-GMO, Gluten Free
Suggested use
Adults take 1 capsule once a day on an empty stomach or as directed by your qualified healthcare professional.
WARNING: Consult a healthcare professional before using this product if you are pregnant, nursing, under the age of 18, are taking medication (especially if taking SSRIs, MAOs, or sedative medications) or have a medical condition; if adverse reactions occur, discontinue use.
KEEP OUT OF THE REACH OF CHILDREN.
STORE IN A COOL, DRY PLACE.
| Supplement facts | ||
| Serving Size: 1 Capsule | ||
| Amount Per Serving | % DV | |
| 5-HTP (5-Hydroxytryptophan) (from Griffonia simplicifolia) (Seed) | 50 mg | † |
| † Daily Value (DV) not established. | ||
Other ingredients
Microcrystalline cellulose, capsule (hydroxypropylmethylcellulose, water), magnesium stearate (vegetable source) and silicon dioxide.
No wheat, gluten, soybeans, dairy, egg, fish/shellfish, peanuts/tree nuts or sesame.
Support Sleep & Wellbeing
Benefits and Features
This essential alpha-amino acid helps make proteins and brain-signaling chemicals like the neurotransmitters serotonin and melatonin.†
Detail Overview
L-Tryptophan is an essential alpha-amino acid that is a precursor to the neurotransmitters serotonin and melatonin. Supplementation with tryptophan has been shown in numerous clinical trials to be safe, well-tolerated, and supportive of well-being, calmness, relaxation, sleep, and appetite control.† For best results, take tryptophan on an empty stomach, or with a small serving of carbohydrates.
SUPPLEMENT FACTS
| Serving Size 4 Capsules | ||
| Amount Per 4 Capsules | % Daily Value | |
|---|---|---|
| L-Tryptophan | 2,000 mg | * |
| * Daily value not established | ||
Other Ingredients:
Vegetarian capsule (hydroxypropyl methylcellulose, water), ascorbyl palmitate, and microcrystalline cellulose.
Suggested Use
Adults: 2-4 capsules at bedtime or as directed by a healthcare professional. Children: as directed by a healthcare professional.
Allergy Statement
Made without common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, soybeans, and sesame. Non-GMO, Vegan, No synthetic colors, or flavors.
Caution
Consult your physician If you are pregnant or nursing, or have a medical condition, or taking prescription drugs, (including antidepressants such as MAOIs and SSRIs, and sedatives), or under the age of 18 years. May cause drowsiness. Do not use with alcoholic beverages or before and while operating a motor vehicle or machinery. KEEP OUT OF REACH OF CHILDREN.
Zenbiome™ Cope – Advanced Psychobiotic Support for Stress, Mood & Cognitive Health, 60 Capsules
Microbiome Labs
Targeted Gut-Brain Axis Support with Psychobiotic 1714™
Zenbiome™ Cope is a clinically formulated psychobiotic supplement designed to support the body’s response to occasional stress, mood changes, and mental fatigue. Powered by the extensively studied Bifidobacterium longum 1714™, and reinforced with essential B vitamins and saffron extract, Zenbiome™ Cope delivers targeted gut-brain axis support to help you stay calm, focused, and resilient throughout daily challenges.
Key Benefits
-
Helps manage occasional stress and mental fatigue
-
Supports calm mood and emotional balance
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Enhances memory, cognitive function, and brainwave activity
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Promotes energy levels and resilience under stress
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Regulates HPA axis and cortisol response
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Supports gut-brain communication through the psychobiome
Science Behind Zenbiome™ Cope
The Gut-Brain Axis & Psychobiotic 1714™
The gut-brain axis is the bidirectional communication network between the gastrointestinal system and the brain. An imbalanced gut microbiome may impact neurotransmitter signaling, mood regulation, and stress responses.
Zenbiome™ Cope features Bifidobacterium longum 1714™, a unique psychobiotic strain that modulates brainwave patterns, reduces perceived stress, and enhances cognitive performance. Clinical trials showed improved memory, focus, and stress-handling ability within 4 weeks of use.
Core Ingredients
Bifidobacterium longum 1714™ (5 Billion CFU)
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Modulates brain activity and cortisol response
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Supports cognitive performance and memory
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Helps maintain mood balance under stress
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Promotes gut microbial health and HPA axis regulation
Vitamin B6 (Pyridoxine Hydrochloride) – 0.85 mg (50% DV)
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Supports neurotransmitter function
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Essential for converting glutamate to GABA (calming pathway)
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Involved in serotonin synthesis
Vitamin B12 (Hydroxocobalamin Acetate) – 1.2 mcg (50% DV)
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Supports serotonin and dopamine pathways
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Maintains homocysteine levels for brain health
-
Contributes to mood and energy regulation
Saffron Stigma Extract (Crocus sativus L.) – 14 mg
-
Helps support healthy mood, relaxation, and nervous system function
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Clinically shown to reduce occasional low mood and emotional tension
Supplement Facts
Serving Size: 1 capsule
Servings Per Container: 60
| Ingredient | Amount | % Daily Value |
|---|---|---|
| Vitamin B6 (pyridoxine HCl) | 0.85 mg | 50% |
| Vitamin B12 (hydroxocobalamin) | 1.2 mcg | 50% |
| Bifidobacterium longum 1714™ | 5 Billion CFU | † |
| Saffron Extract (Crocus sativus L.) | 14 mg | † |
† Daily Value not established
Other Ingredients: Cellulose, vegetable capsule (cellulose and water), magnesium stearate, silicon dioxide
Free from: gluten, dairy, soy, GMOs, artificial preservatives
Shelf-stable, vegan-friendly
Suggested Use
Ages 8+: Take 1 capsule daily in the morning, with or without food, or as directed by your healthcare practitioner.
FAQ
Q: What is a psychobiotic?
A: A psychobiotic is a probiotic strain that positively influences the gut-brain axis and supports mood, stress resilience, and cognition.
Q: Can I take Zenbiome™ Cope with Zenbiome™ Sleep?
A: Yes. Zenbiome™ Cope is formulated for daytime stress support, while Zenbiome™ Sleep helps with nighttime relaxation and sleep quality. They work synergistically.
Q: How long before I notice results?
A: Clinical results with Bifidobacterium 1714™ were observed within 4 weeks. Continued use supports long-term balance.
Q: Is this a replacement for anxiety medication?
A: No. Zenbiome™ Cope is a dietary supplement intended to support occasional stress and mood balance. It is not a medication.
Jarrow Formulas 5-HTP (5-Hydroxytryptophan) is an extract of Griffonia simplicifolia seeds from coastal West Africa. Purity is assured by HPLC. 5-HTP is the direct metabolic precursor to serotonin and is important for the production of melatonin, a hormone secreted by the pineal gland that aids biorhythm regulation.
- Help Support A Balanced Mood
- An Extract of Griffonia simplicifolia Seeds, the Direct Metabolic Precursor to Serotonin. 5-HTP is Important for the Production of Melatonin.
- 100 mg 5-HTP Per Serving
- Vegan, Non-GMO, Gluten Free
Suggested use
Adults take 1 capsule once a day on an empty stomach or as directed by your qualified healthcare professional.
WARNING: Consult a healthcare professional before using this product if you are pregnant, nursing, under the age of 18, are taking medication (especially if taking SSRIs, MAOs, or sedative medications) or have a medical condition; if adverse reactions occur, discontinue use.
Keep out of the reach of children.
| Supplement facts | ||
| Serving Size: 1 Capsule | ||
| Amount Per Serving | % DV | |
| 5-HTP (5-Hydroxytryptophan) (from Griffonia simplicifolia) (Seed) | 100 mg | † |
| † Daily Value (DV) not established. | ||
Other ingredients
Microcrystalline cellulose, capsule (hydroxypropylmethylcellulose, water), magnesium stearate (vegetable source) and silicon dioxide.
No wheat, gluten, soybeans, dairy, egg, fish/shellfish, peanuts/tree nuts or sesame.
FERMENTED MELATONIN
“PRL’s signature FermExcel-100 line is an industry first!”
- Fermented, probiotic-cultured melatonin
- Supports brain, sleep, and immune system health
- Promotes the unique antioxidant activity of melatonin
PRODUCT INFORMATION
Melatonin is a unique, complex molecule that is naturally present in virtually every cell of the body. Melatonin is considered to be the global master bioregulator of the whole body, intercoordinating many of the body’s complex systems, including quality sleep‚ brain support‚ the immune system‚ antioxidants‚ cardiovascular system‚ neuroendocrine system‚ bone health.* The levels of melatonin peak in one’s early years, then as the body ages, the biosynthesis of melatonin begins to decline drastically.
Premier Research Labs Melatonin-ND™ is a nutritional industry first, featuring melatonin in a convenient liquid form that has been cultured with beneficial probiotic organisms for active bio-availability. Melatonin-ND™ is not animal-derived so it is suitable for everyone, including vegetarians and vegans. This premier quality formula is fermented using a unique probiotic culture which allows rapid delivery and superior bioenergetic dynamics. Many people say they can feel the effect of this product the very first time they take it.
What is melatonin?
Melatonin is a unique immunomodulatory compound which supports a wide range of physiological functions. It is produced by the body’s pineal gland, a master gland located in the center of your brain. The secretion of melatonin is inhibited by light and stimulated by darkness. Therefore, melatonin production naturally rises at night. However, this may be compromised in individuals who have altered circadian rhythms or sleep patterns. The use of melatonin to promote restful sleep is well documented and has received substantial publicity for its ability to promote natural sleep patterns and maintain normal circadian rhythms. This extraordinary hormone is one of nature’s most effective antioxidants, offering unsurpassed protection against a broad range of free radicals which can cause cellular damage.
Are you enjoying restful nights and radiant days? If you need more help, then PRL’s Melatonin-ND™ is your product of choice. Experience an industry first with probiotic-fermented melatonin that promotes deep, restful, REM sleep.* You and your family will feel the PRL difference!
RECOMMENDED USAGE
Take 1 dropper just before sleep, or as directed by a health professional. Shake gently before use.
Supplement Facts
Serving Size 1 dropper (1 mL)
Servings Per Container about 54
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