Stress Support

Premier Research Labs

Max B-ND™ Premier Research Labs

From $39.99

Dietary Supplement

2 fl oz (54 mL)

Probiotic-Fermented Vitamin B Complex

STRESS B COMPLEX 2OZ

“PRL’s signature FermExcel-100 line is an industry first!”

Advanced support for liver, brain, energy and mood health*
Promotes adrenal, immune system, and cardiovascular system health*
Contains 13 active B-vitamin forms

PRODUCT INFORMATION

Do you feel fatigue or occasional stress from time to time? In this era of “more is more”, many tasks can vie for your attention and pull you in different directions all too often. An overly busy lifestyle can actually be at the core of some health concerns. During times of stress, your body’s capacity to adapt may be reduced without sufficient nutritional support. Supporting the system with Max B-ND™ offers advanced support for the liver, the brain, the immune system, adrenal glands, cardiovascular system, mood balance and energy levels.

Max B-ND^TM is a nutritional industry first - with never before available probiotic-fermented B vitamins. This product contains a high-energy B vitamin complex that delivers premier nutritional support.* Each 1/2 tsp. supplies high energy vitamin B forms including B5 as pantothenic acid, vitamin B2 in the riboflavin-5-phosphate form and more.

This B vitamin-rich formula offers advanced support for the liver, the immune system, adrenal glands, mood balance and energy levels.*

Healthful diets with adequate folate may reduce a women's risk of having a child with a brain or spinal cord defect.

ND Technology™ (Novel Micro-cultured Delivery)
This premier quality formula is fermented using a unique probiotic culture which allows rapid oral delivery with superior bioenergetic properties. Many people say they can feel the effect of this product the very first time they take it.

RECOMMENDED USAGE

Take 1/2 teaspoon mixed in 1/4 cup water daily. Shake before use. Refrigerate after opening.

Supplement Facts

Serving Size 1/2 Teaspoon (2.5 mL)
Servings Per Container 21/94

Enzyme Science

Serrapeptase Pro 120 capsules Enzyme Science

$57.50

Overview

Serrapeptase Pro by Enzyme Science is a high-potency systemic enzyme formula designed to support recovery, circulation and the body’s natural response to physiological stress.

This formula combines serrapeptase, a well-studied proteolytic enzyme, with Protease Thera-blend® and supportive minerals. Proteolytic enzymes help break down proteins and may assist the body in clearing damaged or unnecessary proteins during normal recovery processes.

Serrapeptase has been used for decades in Europe and Asia and has been studied for its ability to support tissue recovery, circulation and immune balance. When taken on an empty stomach, the enzyme is absorbed into the bloodstream where it can support systemic enzyme activity throughout the body. :contentReference[oaicite:0]{index=0}

Key Benefits

Supports the body’s natural response to systemic stress
Helps support circulation and cardiovascular health
Supports tissue recovery after physical exertion
Provides systemic proteolytic enzyme activity
Supports immune and inflammatory balance
Includes Thera-blend® enzymes active across a wide pH range

Supplement Facts

Serving Size: 1 Capsule

Servings Per Container: 120

Amount Per Serving	% Daily Value
Calcium (from Calcium Citrate)	17.5 mg (1%)
Magnesium (from Magnesium Citrate)	0.1 mg (<1%)
Protease Thera-blend®	80,000 HUT †
Serrapeptase	100,000 SPU †

† Daily Value not established.

Other Ingredients: Vegetarian capsule (HPMC, water).

Free From: Casein, crustaceans, eggs, fish, gluten, milk, nuts, sesame, shellfish, soy and wheat. No artificial colors, fillers or flavors.

How It Works

Serrapeptase is a proteolytic enzyme originally isolated from the bacterium Serratia marcescens. It helps break down non-living proteins and protein debris that can accumulate during the body’s natural repair processes.

Once absorbed into circulation, serrapeptase may help support healthy inflammatory balance and assist the body’s natural recovery mechanisms.

Protease Thera-blend® is a combination of multiple proteolytic enzymes that remain active across a broad pH range, allowing the formula to function effectively in different environments within the body.

The formula also includes small amounts of calcium and magnesium to help improve digestive comfort when using systemic enzymes.

Suggested Use

Take 1 capsule daily on an empty stomach, either 1 hour before or 2 hours after a meal, or as recommended by a healthcare practitioner.

FAQ

Why should serrapeptase be taken on an empty stomach?
When taken without food, the enzyme can be absorbed into the bloodstream and provide systemic enzyme support rather than being used only for digestion.

What is serrapeptase used for?
Serrapeptase is commonly used to support tissue recovery, circulation, immune balance and the body’s natural response to physiological stress.

What does SPU mean?
SPU (Serrapeptase Units) measures the enzymatic activity of serrapeptase and reflects the potency of the enzyme.

Is this product vegetarian?
Yes. The capsules are plant-based and the formula does not contain common allergens.

Can active individuals benefit from this formula?
Yes. Proteolytic enzymes are commonly used by individuals with active lifestyles to support recovery and overall systemic enzyme activity.

Storage

Store in a cool, dry place with the container tightly closed.

Microbiome Labs

Zenbiome Sleep 30 capsules Microbiome Labs

$64.08

Zenbiome™ Sleep – Psychobiotic Support for Restful Sleep & Stress Recovery, 30 Capsules

Microbiome Labs

Targeted Gut-Brain Axis Support for Sleep Quality, Mood, and Stress Resilience

Zenbiome™ Sleep is a cutting-edge psychobiotic formula designed to support individuals who experience occasional sleeplessness, disrupted sleep cycles, or stress-related fatigue. Featuring the clinically validated strain Bifidobacterium longum 1714™, along with lemon balm extract and L-theanine, this supplement promotes a calm mind, enhanced cognitive performance, and restorative sleep through the gut-brain axis.

Unlike sedatives or melatonin, Zenbiome™ Sleep addresses underlying causes of sleep disturbances by supporting healthy brain chemistry, nervous system function, and microbial balance.

Key Benefits

Promotes relaxation and quality sleep
Helps reset the natural sleep-wake cycle
Reduces cortisol levels and supports a healthy HPA axis response
Enhances mood, cognitive clarity, and emotional balance
Supports tryptophan metabolism and serotonin/melatonin pathways
Encourages alpha brainwave activity for calm wakefulness
Shelf-stable, non-habit forming, and well-tolerated

Active Ingredients

Bifidobacterium longum 1714™ (5 Billion CFU)

A clinically studied psychobiotic strain originally isolated from the healthy human gut.
Shown to:

Improve sleep duration and quality under stress
Reduce perceived stress and cortisol
Enhance mental energy, memory, and mood
Promote neuroprotection by shifting tryptophan metabolism away from neurotoxicity

Lemon Balm Leaf Extract (Melissa officinalis L.) – 200 mg

Traditionally used for restlessness, nervous tension, and sleep disturbances
Promotes calm and relaxation without sedation

L-Theanine – 200 mg

An amino acid that promotes alpha brainwaves and a relaxed mental state
Supports stress reduction and sleep onset latency without grogginess

Supplement Facts

Serving Size: 1 capsule
Servings Per Container: 30

Ingredient	Amount
Lemon Balm Extract	200 mg
L-Theanine	200 mg
Bifidobacterium longum 1714™	5 Billion CFU

Other Ingredients: Vegetable capsule (cellulose and water), cellulose, magnesium stearate, silicon dioxide
Free from: GMOs, gluten, soy, dairy, artificial additives

Suggested Use

Ages 8+: Take 1 capsule in the evening, with or without food, or as directed by your healthcare practitioner.

Clinical Highlights

Human Study (2020): Improved sleep indices during exam stress (PMID: 34589719)
Human Study (2016): Reduced perceived stress, enhanced memory, lower cortisol (PMID: 27801892)
Human Study (2019): Increased vitality, reduced fatigue, and improved social function (PMID: 30998517)

Frequently Asked Questions

Q: How is this different from melatonin?
A: Zenbiome™ Sleep does not contain melatonin. It works by supporting the body’s natural sleep processes via the gut-brain axis, making it suitable for long-term use.

Q: Will I feel drowsy the next morning?
A: No. The formula is designed to promote restful sleep without residual grogginess.

Q: Can I use this with Zenbiome™ Cope or Zenbiome™ DUAL?
A: Yes. Zenbiome™ Sleep works synergistically with other psychobiotic products for 24-hour stress and sleep support.

Q: Is it habit-forming?
A: No. It contains non-habit-forming natural ingredients and is safe for daily use.

Integrative Therapeutics

Cortisol Manager Tablets Integrative Therapeutics

From $26.75

SUPPORTS BALANCED CORTISOL & HEALTHY STRESS RESPONSE*

The ingredients in Cortisol Manager support healthy cortisol levels.* Cortisol is one of the most important hormones involved in the adaptation process. By supporting balanced cortisol and a healthy stress response, Cortisol Manager also promotes relaxation to support restful sleep.*

THE ROLE OF CORTISOL IN TIMES OF STRESS

Cortisol is a hormone produced in the adrenal cortex that is released during times of stress. Variations in cortisol secretion can indicate how well the body is coping with stress. Cortisol homeostasis is typically characterized by peak secretion during the early morning hours with a gradual decline throughout the day. Because of its central role as a key stress hormone, cortisol is often thought of as a bridge between stress and its health impact.

WITH HERBAL INGREDIENTS

The ingredients in Cortisol Manager help support a balanced, adaptive cortisol response to stress.* Cortisol Manager contains a stress-reducing proprietary blend of Sensoril® brand ashwagandha (Withania somnifera) and L-theanine.* A proprietary blend of Magnolia (Magnolia officinalis) and epimedium (Epimedium koreanum), as well as phosphatidylserine from soy lecithin are included in Cortisol Manager.

A 2008 placebo-controlled clinical trial showed that Sensoril® ashwagandha significantly reduced serum cortisol levels and helped manage stress compared to placebo, in subjects experiencing higher levels of stress.*¹

The ingredients in Cortisol Manager help support relaxation to promote restful sleep.* They also help stabilize the stress hormone cortisol to further support a healthy stress response.*

REFERENCES

Auddy B et al. J Am Nutraceutical Assoc. 2008;11(1):50-6.
Nobre AC et al. Asia Pac J Clin Nutr. 2008;17(S1):167-68.

DIRECTIONS

Cortisol Manager® Directions and/or Dosage Adults take 1 tablet before bedtime or as recommended by a healthcare professional. Increase to 2 tablets during times of high stress. For nightly use.

Warning Do not use if you are pregnant or nursing. If you are taking any medications, consult a healthcare professional before use. Individuals with diabetes should monitor blood glucose levels closely while taking this product. Keep out of reach of children. Safety sealed with inner seal. Do not use if seal is broken or missing. Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.

FAQS

Q: Can Cortisol Manager® be taken during the day? Will it cause drowsiness?

A: While some individuals do take Cortisol Manager® during the day, caution should be used as it will cause you to relax and drowsiness may occur.†

Q: Can Cortisol Manager® be helpful for someone with low cortisol levels?

A: While the ingredients do have a modulating effect, the small scale study shows a rather significant reduction in cortisol levels. Therefore, we would not recommend Cortisol Manager® for someone with low cortisol.

Q: What is the source of the phosphatidylserine in Cortisol Manager®?

A:

The source of the phosphatidylserine in Cortisol Manager® is vegetable glycerin. The glycerin, in turn, is derived from a highly purified, refined soybean oil, which contains no allergenic proteins.

Q: Does Cortisol Manager Contain Soy?

A:

Yes. Cortisol Manager contains phosphatidylserine sourced from soy. If your patients require a non-soy formula, you may want to consider standalone soy-free phosphatidylserine.

Q: Can Cortisol Manager be used in mid or late-stage stress response?

A: Though typically used within the early-stage of the stress response, Cortisol Manager can be used in the mid and late stages – particularly within the mid-stage when additional energy and stress support is needed.* The HPA Optimization program highlights key nutrient support that is appropriate for the mid and late stages, such as the adaptogenic herbal combination of HPA Adapt, for mid-stage, and CortiVive for late stage, which supports healthy cortisol production and healthy adrenal cortex function.

Q: If two tablets are taken per day, should these be taken at the same time or in divided dosing?

A:

While there may be instances when divided dosing is indicated, typically, if two tablets are taken per day, they can be taken at the same time.

Q: Can the tablets be cut or broken?

A:

Yes. The tablets are easily broken in half and can be consumed this way.

Q: Does it matter when during the day Cortisol Manager is taken?

A:

Clinical judgment will guide timing; however, Cortisol Manager is generally used in the evening or when cortisol secretion is high.

Q: As a member of the nightshade family, does ashwagandha pose any potential dangers or side effects?

A: No, not when used properly. Research has shown that ashwagandha offers safe and effective support for the body during times of stress.* Unfortunately, there are some sources indicating that all plants of the Solanaceae or nightshade family (potatoes, tomatoes, peppers, eggplant, and ashwagandha, included) should be avoided because of their potential to reduce immune system function. However, many of these same plants and herbs have been used as food staples and medicines for thousands of years. These compounds, found in green part of the vegetables, may cause adverse effects in humans when taken at unrealistically high levels.

INGREDIENTS	Amount / Serving	%DV
Serving Size: 2 tablets
Calories	5	--
Total Carbohydrate	1g	<1%†
Sodium	5mg	<1%
Stress-Reducing Proprietary Blend:	500mg	**
- Ashwagandha (Withania somnifera) Extract
(Sensoril® brand) (root, leaf)
- L-theanine
Cortisol-Reducing Proprietary Blend:	450mg	**
- Magnolia (Magnolia officinalis) Extract
standardized to 2% honokiol (6 mg) and
1% magnolol (3 mg)
- Epimedium (Epimedium spp.) Extract
Phosphatidylserine (from soybean lecithin)	100mg	**

**Daily Value (DV) not established

†Percent daily value is based on a 2000 calorie diet

Other Ingredients: cellulose, sodium croscarmellose, stearic acid, calcium silicate, magnesium stearate, silica, hypromellose, glycerin

Allergy Research Group

Herbal Adapt HPA Axis Restore 60 capsules Allergy Research Group

$34.89

Overview

Herbal Adapt HPA Axis Restore 60 capsules is an adaptogenic herbal formula designed to support a healthy stress response, balanced mood, physical resilience, and HPA axis function. It combines five standardized botanical extracts - ashwagandha, holy basil, rhodiola, licorice, and ginger - in a focused daily formula for individuals seeking practitioner-style support for stress adaptation and overall resilience.

This blend is built around well-known adaptogenic herbs traditionally used to help the body respond to physical and mental stressors. With standardized extracts and a clean capsule format, it is a practical option for those looking for an adaptogen supplement for stress support, mood balance, and HPA axis health.

Key Benefits

Supports a healthy response to everyday stress
Promotes balanced mood and physical resilience
Provides standardized adaptogenic herbal extracts
Supports HPA axis function and stress adaptation
Includes ashwagandha, holy basil, and rhodiola
Enhanced with licorice root and ginger extract
Convenient capsule format for daily use

Supplement Facts

Serving Size: 1 Capsule

Servings Per Container: 60

Ingredient	Amount Per Serving	% Daily Value
Ashwagandha Root Extract (standardized to 5% withanolides)	200 mg	Daily Value not established
Holy Basil Leaf Extract (standardized to 2.5% ursolic acid)	150 mg	Daily Value not established
Rhodiola Root Extract (standardized to 3% rosavins and 1% salidrosides)	100 mg	Daily Value not established
Licorice Root Extract (standardized to 20% glycyrrhizic acid)	50 mg	Daily Value not established
Ginger Rhizome Extract (standardized to 5% gingerols)	25 mg	Daily Value not established

Other Ingredients: Hydroxypropyl methylcellulose, microcrystalline cellulose, rice hull concentrate, gum arabic, sunflower oil.

Ingredient Breakdown

Ingredient	Purpose in the Formula
Ashwagandha Root Extract	Core adaptogen for stress resilience, mood balance, and physical adaptation
Holy Basil Leaf Extract	Adaptogenic botanical used to support calm resilience and daily stress balance
Rhodiola Root Extract	Adaptogen commonly used for mental stamina, energy resilience, and stress support
Licorice Root Extract	Traditional botanical included to complement stress-response support
Ginger Rhizome Extract	Supportive botanical added to round out the formula

How It Works

Herbal Adapt HPA Axis Restore is built around a combination of standardized adaptogenic herbs that work together to support the body’s ability to respond to daily physical and mental stress. Ashwagandha, holy basil, and rhodiola are the central adaptogens in the formula and are widely used in stress-support protocols focused on resilience, mood balance, and sustained daily function.

Ashwagandha root extract is standardized to 5% withanolides, while holy basil is standardized to 2.5% ursolic acid and rhodiola to 3% rosavins and 1% salidrosides. These standardized forms help preserve consistency and make the formula more aligned with practitioner-grade herbal support.

Licorice root extract and ginger extract are included as complementary botanicals to round out the blend. Together, these ingredients create a more complete formula for those looking for an adaptogen supplement for HPA axis support, balanced mood, and stress recovery rather than a single-herb product.

Suggested Use

As a dietary supplement, take 1 capsule twice daily away from meals, or as directed by a healthcare practitioner.

FAQ

What does Herbal Adapt HPA Axis Restore support?

It is designed to support a healthy stress response, HPA axis balance, physical resilience, and balanced mood.

What adaptogens are included in this formula?

The formula includes ashwagandha, holy basil, and rhodiola, along with licorice root and ginger extract.

Is this a standardized herbal formula?

Yes. The key herbs are provided as standardized extracts, including withanolides, ursolic acid, rosavins, salidrosides, glycyrrhizic acid, and gingerols.

How should it be taken?

Take 1 capsule twice daily away from meals, or as directed by a healthcare practitioner.

Who might consider this product?

It may be useful for individuals looking for daily herbal support for stress adaptation, mood balance, and overall resilience.

Storage

Store in a cool, dry place, tightly capped, away from light. Keep out of the reach of children. Use only if safety seal is intact. Variations in product color may occur.

Klair Labs

L-Tyrosine 500 mg 100 capsules Klaire Labs / SFI Health

$27.99

Supports Healthy Thyroid Function

Benefits and Features

Supports dopamine synthesis for emotional wellness and cognitive function and acts as a thyroid hormone precursor to support healthy thyroid function.

Detail Overview

Important for the formation of thyroid hormones and brain-stimulating catecholamines that support stress response mechanisms. Supports your body in making T3 and T4 thyroid hormones and brain-stimulating chemicals like dopamine, norepinephrine, and epinephrine which support stress response mechanisms, emotional wellness, and the ability to concentrate.^†

SUPPLEMENT FACTS

Amount Per Capsule		% Daily Value
Serving Size 1 Capsule
L-Tyrosine (free form)	500 mg	*

* Daily value not established

Other Ingredients:

Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, microcrystalline cellulose, and silicon dioxide.

Suggested Use

Adults: 1 capsule, 1 to 4 times daily or as directed by a healthcare professional. Children: As directed by a healthcare professional.

Allergy Statement

Made without common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, soybeans, and sesame. Non-GMO, No synthetic colors, flavors or preservatives.

Caution

Consult your physician If you are pregnant or nursing, or have a medical condition, or taking prescription drugs, or under the age of 18 years. KEEP OUT OF REACH OF CHILDREN.

Jarrow Formulas

Theanine 200mg 60 capsules Jarrow Formulas

$23.24

Real Mushrooms

Turkey Tail Capsules Real Mushrooms

~~$34.95~~From $33.20

Supplement Facts
Serving Size: 2/3 capsules
	Amount Per Serving	%Daily Value
Organic Turkey Tail Mushroom Extract Trametes versicolor	1000 mg	*
Beta-(1,3)(1,6)-glucans	300 mg
*Daily Value (DV) not established.