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3000 mcg with Folate
Product Description
B12 Adenosylcobalamin 3000 mcg with Folate delivers a high-potency, bioactive form of vitamin B12 to support cellular energy production, nerve health, cognitive function, and red blood cell formation in lozenge form.* Combined with folate, this formula promotes healthy methylation, neurotransmitter synthesis, and homocysteine balance for neurological and metabolic support.
Support Mitochondrial Energy and Neurological Health with a High-Potency, Bioactive B12 Formula*
What It Does
B12 Adenosylcobalamin 3000 mcg with Folate supports cellular energy production, healthy nerve structure and function, and optimal red blood cell formation.* This advanced formula contributes to balanced methylation, neurotransmitter synthesis, and homocysteine metabolism for metabolic and cognitive well-being.*
How It Works
• Adenosylcobalamin (active B12, 3000 mcg): Directly supports mitochondrial energy production by facilitating the conversion of methylmalonyl-CoA to succinyl-CoA in the citric acid cycle, essential for ATP synthesis.*[1,4,11]
• Folate: Supports normal methylation and neurotransmitter synthesis, while also working in tandem with vitamin B12 to support homocysteine levels and red blood cell production.*[1,8,9]
• Vitamin B12 (as adenosylcobalamin): Essential for myelin sheath integrity, supporting nerve conduction, emotional health, and cognitive function, especially in the aging population or those on medications that affect vitamin B12 absorption.*[2,3,5,7,10]
• High-dose oral vitamin B12: Shown in systematic reviews to be useful for improving B12.*[11]
Who It’s For
Ideal for individuals with increased need for bioactive B12, such as those following vegetarian or vegan diets, older adults, or those seeking to optimize their vitamin B12 status.*
Special Features
Provides a neurologically active, mitochondrial-ready form of B12 in lozenge format to support optimal absorption.
References
1. Baltrusch S. Biomed Res Int. 2021;2021:9968228. doi:10.1155/2021/9968228
2. Pawlak R, et al. Eur J Clin Nutr. 2014;68(5):541–548.
3. Lachner C, et al. J Neuropsychiatry Clin Neurosci. 2012;24(1):5–15.
4. Mumtaz H, et al. Ann Med Surg (Lond). 2022;82:104762. doi:10.1016/j.amsu.2022.104762
5. Infante M, et al. World J Diabetes. 2021;12(7):916–931.
6. Ueno A, et al. Nutrients. 2022;14(7):1494. doi:10.3390/nu14071494
7. Sangle P, et al. Cureus. 2020;12(10):e11169. doi:10.7759/cureus.11169
8. Syed EU, et al. Open Neurol J. 2013;7:44–48.
9. Calderon-Ospina CA, Nava-Mesa MO. CNS Neurosci Ther. 2020;26(1):5–13.
10. Beaudry-Richard A, et al. Ann Neurol. doi:10.1002/ana.27200
11. Wang H, et al. Cochrane Database Syst Rev. 2018;3(3):CD004655. doi:10.1002/14651858.CD004655.pub3
Suggested use:
Overview
Pantothenic Acid 500 mg provides vitamin B5 in the form of calcium pantothenate to support energy metabolism and normal cellular function. Pantothenic acid is an essential B vitamin involved in the metabolism of carbohydrates, fats, and proteins.
Vitamin B5 also plays an important role in the production of coenzyme A (CoA), a compound necessary for energy production and the synthesis of important biological molecules in the body.
Key Benefits
- Provides 500 mg pantothenic acid (vitamin B5) per capsule
- Supports energy metabolism
- Supports normal adrenal function
- Supports healthy skin, hair, and nervous system function
- Contributes to red blood cell formation
How It Works
Pantothenic acid is a precursor of coenzyme A (CoA), a molecule required for many metabolic pathways in the body. CoA participates in the metabolism of carbohydrates, fatty acids, and amino acids.
Through these processes, vitamin B5 helps support cellular energy production and the synthesis of hormones, neurotransmitters, and structural components needed for normal physiological function.
Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 90
| Amount Per Serving | mg | % Daily Value |
|---|---|---|
| Pantothenic Acid (as Calcium Pantothenate) | 500 mg | 10,000% |
| Calcium (as Calcium Pantothenate) | 42 mg | 3% |
Other Ingredients: Hydroxypropyl methylcellulose, L-leucine.
Suggested Use
Take 1 capsule three times daily with meals, or as directed by a healthcare practitioner.
Storage
Store in a cool, dry place, tightly capped and away from light. Keep out of reach of children.
Two active forms for brain health & dopamine production, lozenge
Vitamin B12 is essential for brain health and function, energy metabolism and the production of red blood cells. B12 Elite combines two active forms of this crucial vitamin in a single vegetarian lozenge.
What Is B12 Elite?
Vitamin B12 is essential for proper biological processes. Serum levels of vitamin B12 can decline over time, and because it’s found primarily in animal products, vegetarian diets may not provide sufficient B12. Our B12 Elite gives you 500 mcg each of adenosylcobalamin and methylcobalamin: two neurologically active forms of B12.
B12 Elite combines two forms of this vitamin—both of which are essential for proper bodily and neurological function.
B12 Elite Benefits
- Novel formula delivers two forms of bioactive B12
- Helps protect delicate brain cells
- Promotes healthy dopamine levels
- Encourages healthy B12 serum levels
- Promotes overall brain health
Two Active Forms of Vitamin B12
Vitamin B12 (also called cobalamin) is a water-soluble vitamin that plays a vital role in the health of your nervous system, blood cells and even your DNA (B12 helps protect delicate parts of your chromosomes). Our B12 Elite formula includes two bioactive forms of cobalamin that make it easier for your body to absorb and access vitamin B12’s health benefits.
hy Should I Supplement With B12 Elite?
Whether it's promoting brain health, supporting the nervous system or maintaining cellular health and energy levels, vitamin B12 is essential for us to thrive. But while this vitamin is excellent for our health, more and more of us are finding less and less in our systems because we don't produce it naturally. Changes in eating habits, like relying more on plant-based diets, along with the one thing we can’t change, the passage of time, are also impacting the levels of this vital nutrient.
Luckily, our experts saw the need and formulated our B12 Elite to help you fill in any of your gaps. We didn't just throw any old form of the vitamin in there. B12 Elite uses the active forms of B12. So it's easier for your body to absorb and access the health benefits right away. This tasty vegetarian lozenge has no artificial flavors, colors or sweeteners, and has absolutely no added sugar.
So start promoting your brain health, nervous system, blood cells and more with B12 Elite from Life Extension.
Vitamin B12 is good for you. But many people don’t get sufficient B12 from their diets alone. Reasons range from age-related insufficiency to dietary intake: B12 comes primarily from animal sources, so those following a vegetarian diet may not get enough.
Our new B12 Elite combines two types of cobalamin: adenosylcobalamin and methylcobalamin. These are “active” forms—meaning your body can make use of them right away.
Adenosylcobalamin helps preserve neuronal function
Leucine-Rich Repeat Kinase 2 (LRRK2) is a type of enzyme that modifies other proteins by adding phosphate groups. Inhibiting the activity of this enzyme has been associated with helping to preserve neuronal tissue.
A series of preclinical studies has shown that the adenosylcobalamin form of B12 can inhibit the activity of multiple LRRK2 variants in neurons by decreasing phosphorylation (the addition of phosphate groups to amino acids).
These studies found that adenosylcobalamin helped regulate healthy release of dopamine, a neurotransmitter that plays an important role in cognitive functions such as motor control, arousal, reinforcement and reward.
A cofactor for energy metabolism
Adenosylcobalamin is active in the mitochondria, the powerhouses of your cells. It’s required as a cofactor for the synthesis of succinyl-CoA, a compound that supports cellular energy metabolism.
Methylcobalamin for cellular health & beyond
Methylcobalamin is another neurologically active form of B12 (though in different ways than adenosylcobalamin). Methylcobalamin supports the central nervous system, and it’s essential for the replication and growth of cells.
Methylcobalamin helps to maintain already healthy homocysteine levels. Inhibiting excess levels of this compound is key to maintaining healthy cardiovascular and neurological function.
B12 for a healthy brain and more
This B12 formula combines methylcobalamin and adenosylcobalamin to offer optimal cognitive support. Want the health benefits of the full range of the B vitamins? We also offer our BioActive Complete B-Complex formula: a wide-spectrum of B vitamins for whole-body health.
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- KEEP OUT OF REACH OF CHILDREN
- DO NOT EXCEED RECOMMENDED DOSE
- Do not purchase if outer seal is broken or damaged.
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
P-5-P – Active Vitamin B6 for Amino Acid and Neurotransmitter Support
P-5-P provides pyridoxal 5’-phosphate (P-5-P), the active coenzyme form of vitamin B6, to support amino acid metabolism, neurotransmitter synthesis, liver function, and overall nervous system health.
This well-absorbed, bioactive form of B6 bypasses the need for conversion in the liver, making it ideal for individuals with compromised B6 metabolism.
Key Benefits*
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Supports amino acid metabolism
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Promotes neurotransmitter production (e.g., serotonin, dopamine, GABA)
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Aids in liver function and red blood cell formation
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Helps maintain a healthy nervous system
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Provides B6 in its active, ready-to-use form
Supplement Facts (per capsule)
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Vitamin B6 (as pyridoxal 5’-phosphate): 30 mg (1765% DV)
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Other ingredients: Microcrystalline cellulose, vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine
Suggested Use
Take 1 capsule daily with food or as directed by your healthcare professional.
Highlights
✔ Active coenzyme form of B6
✔ Hypoallergenic and well-tolerated
✔ Gluten-free, dairy-free, soy-free
✔ Suitable for vegetarians
| Serving Size 1 Capsule | ||
| Amount Per Capsule | % Daily Value | |
|---|---|---|
| Vitamin B6 ( as pyridoxal 5'- phosphate) | 30 mg | 1,765% |
Other Ingredients:
Microcrystalline cellulose, vegetarian capsule (hydroxypropyl methylcellulose, water), and L-leucine.
Suggested Use
Adults: 1 capsule daily with food or as directed by a healthcare professional. Children: As directed by a healthcare professional.
Allergy Statement
Made without common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, soybeans, and sesame. Non-GMO, Vegan/ No synthetic colors, flavors, or preservatives.
Caution
Consult with your physician if you are pregnant or nursing, or have any medical condition, or taking prescription drugs, or under the age of 18 years. KEEP OUT OF REACH OF CHILDREN.
Hair and nail support
Benefits and Features
- Biotin helps turn protein, fat, and carbohydrates you eat into energy your body needs.
- Supplementing with this essential B vitamin may also promote healthier hair, skin, and nails if you are biotin deficient.
Detail Overview
An essential B vitamin required for several enzyme systems involving glucose metabolism, fatty acid synthesis, nervous system function, and skin and hair nutrition. Extra biotin can be especially useful for diabetic patients, bariatric surgery patients, and others with compromised absorption or higher demand of this nutrient.
SUPPLEMENT FACTS
| Serving Size 1 Capsule | ||
| Amount Per Capsule | % Daily Value | |
|---|---|---|
| Biotin (as D-biotin) | 5,000 mcg | 16,667% |
Other Ingredients:
Microcrystalline cellulose, vegetarian capsule (hydroxypropyl methylcellulose, water), and silicon dioxide.
Suggested Use
Adults: 1 capsule daily with food or as directed by a healthcare professional. Children: As directed by a healthcare practitioner.
Allergy Statement
Made without the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, soybeans, corn, sesame, and yeast. No synthetic colors, flavors, or preservatives. Vegan and non-GMO.
Caution
Consult with your physician if you are pregnant or nursing, or have any medical condition, or taking prescription drugs, or under the age of 18 years. KEEP OUT OF REACH OF CHILDREN.
Multi-benefit health essential
Vitamin B6 is a water-soluble vitamin found naturally in many foods, while fortified in others. If you aren’t getting enough, supplementing helps support cardiovascular and neurological health.
Since your body doesn’t produce vitamin B6, it must be obtained through diet or supplementation.
Vitamin B6 Benefits
- Helps support cardiovascular & neurological health
- Helps maintain homocysteine levels already within normal range
- A cofactor in more than 160 enzyme-driven reactions
Sometimes Food Sources Aren’t Enough
Vitamin B6 is found in foods such as eggs, brewer’s yeast, carrots, chicken, fish, brown rice, whole grains and cabbage. While most people get enough vitamin B6 from food, that's not always the case. If you need help maintaining vitamin B6 levels, there are a host of whole-body health benefits it can support.
Vitamin B6, or pyridoxine, is a component of the vitamin B complex and necessary for optimal health. In its active form, pyridoxal 5-phosphate (PLP), vitamin B6 is a cofactor in more than 160 enzyme-driven reactions in the body that affect amino acid transformation, synthesis and breakdown of neurotransmitters, cellular energy production and use, immune function, methylation and DNA synthesis and repair.
While most people get enough B6 from food sources, some people are B6 deficient. Optimal blood levels of PLP may help support cardiovascular and neurological health. Through its role as a methylator, vitamin B6 (along with B12 and folate) helps maintain homocysteine levels already within the normal range. One study noted a connection between vitamin B6 levels, high homocysteine levels and increased mortality.
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Peripheral neuropathy may occur when pyridoxine HCl is taken in excess of 300 mg daily. If this occurs, reduce intake or discontinue product. |
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- KEEP OUT OF REACH OF CHILDREN
- DO NOT EXCEED RECOMMENDED DOSE
- Do not purchase if outer seal is broken or damaged.
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Jarrow Formulas B-Right® is an optimized B-Complex featuring the forms of vitamins B1 (thiamin), B2 (riboflavin), B5 (pantethine), B6 (P-5-P), B12 (methylcobalamin), and B9 (methyl folate) that are efficiently utilized by the body. B vitamins play an important role in the body, including cellular energy production, immune health, and stress management.
- Supports Cellular Energy, Immune Health and Stress Management
- Optimized B-Complex with Methylcobalamin B12 + Pantethine B5 + P-5-P B6
Adults take 1 capsule once a day with a meal or as directed by your qualified healthcare professional.
WARNING: This product contains Biotin which may interfere with lab/blood tests, and Nicotinic Acid which may cause a niacin flush, especially on an empty stomach. Symptoms for Nicotinic acid are transient and may include burning, tingling, itching sensations, reddening of the skin, dizziness, and/or shortness of breath. If a severe reaction occurs, drink plenty of water and discontinue use. Consult a healthcare professional before using this product if you are pregnant, nursing, under the age of 18, are taking medication (especially antiepileptic and chemotherapy) or have a medical condition; if adverse reactions occur, discontinue use.
Keep out of the reach of children.
| Supplement facts | ||
| Serving Size: 1 Capsule | ||
| Amount Per Serving | %DV | |
| Thiamin (as Thiamine Mononitrate) | 25 mg | 2,083% |
| Riboflavin | 25 mg | 1,923% |
| Niacin (as Nicotinic Acid) | 25 mg NE§ | 156% |
| Vitamin B6 (as Pyridoxine HCl [25 mg] and Pyridoxal 5-Phosphate [10 mg]) | 35 mg | 2,059% |
| Folate (400 mcg as (6S)-5-MTHF [from (6S)-5-Methyltetrahydrofolate Glucosamine Salt) | 680 mcg DFE‡ | 170% |
| Vitamin B12 (as Methylcobalamin) | 100 mcg | 4,167% |
| Biotin (as d-Biotin) | 300 mcg | 1,000% |
| Pantothenic Acid (as Calcium D-Pantothenate) | 100 mg | 2,000% |
| Choline (as Choline Bitartrate) | 50 mg | 9% |
| Pantethine | 25 mg | † |
| Inositol | 50 mg | † |
| †Daily Value (DV) not established. ‡Dietary Folate Equivalents. §Niacin Equivalents. |
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Other ingredients
Capsule (hydroxypropylmethylcellulose, water), microcrystalline cellulose, silicon dioxide, calcium phosphate, magnesium stearate (vegetable source), and stearic acid (vegetable source).
No wheat, gluten, soybeans, dairy, egg, fish/shellfish, peanuts/tree nuts or sesame.
Overview
Niacin (Vitamin B3) provides 250 mg of niacin per capsule. Niacin is an essential B vitamin involved in many metabolic processes and plays a central role in cellular energy production.
Niacin is a key component of the coenzymes NAD/NADH and NADP/NADPH, which participate in numerous biochemical reactions related to energy metabolism and cellular function.
Key Benefits
- 250 mg niacin per capsule
- Supports cellular energy metabolism
- Important for NAD and NADP coenzyme production
- Supports normal metabolic processes
- Convenient capsule format
How It Works
Niacin is converted in the body into NAD (nicotinamide adenine dinucleotide) and NADP (nicotinamide adenine dinucleotide phosphate). These coenzymes are essential for redox reactions that occur throughout the body.
These metabolic pathways are involved in energy production, cellular signaling, and the metabolism of carbohydrates, fats, and proteins.
Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 90
| Amount Per Serving | Amount | % Daily Value |
|---|---|---|
| Niacin | 250 mg NE | 1563% |
Other Ingredients: Hydroxypropyl methylcellulose, L-leucine.
Suggested Use
Take 1 capsule three times daily with meals, or as directed by a healthcare practitioner.
Important Information
Niacin may cause temporary skin flushing. Do not exceed the recommended dose without supervision from a healthcare practitioner.
Storage
Store in a cool, dry place, tightly capped and away from light. Keep out of reach of children.
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