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Fisetin has loads of health benefits. But fisetin is rapidly metabolized during the digestive process. So we’ve created a formula that helps preserve fisetin, so you get the maximum benefit.
What Is Bio-Fisetin?
We’ve combined fisetin with special galactomannan compounds from fenugreek seeds. Doing so protects fisetin during digestion, a technique we pioneered with our flagship Curcumin Elite™ formula. The result: better bioavailability—up to 25 times better than unformulated fisetin—so your body gets the maximum health benefits.
Most forms of fisetin have low bioavailability, but not Bio-Fisetin—thanks to special fenugreek fibers called galactomannans.
Bio-Fisetin Benefits
- Maximizes fisetin bioavailability with special fenugreek fiber coating
- Helps your body clear senescent cells, supporting cellular health and longevity
- Supports brain health and helps protect brain function
- Supports healthy glucose metabolism, which helps protect eye and kidney health
Making a more bioavailable fisetin
When you ingest fisetin, enzymes in your digestive system soon break it down to various metabolites. To shield it from being quickly broken down, we’ve combined fisetin with galactomannan fibers from fenugreek seeds, a technique we pioneered with our Curcumin Elite™ formula. Doing so preserves fisetin through your digestive system, allowing it to circulate: Bio-Fisetin is up to 25 times more bioavailable than standard fisetin supplements.
By combining fisetin with fenugreek fibers, we’re able to create a fisetin formula that is up to 25 times more bioavailable. This means that the fisetin in our Bio-Fisetin supplement circulates longer than traditional fisetin. So what good can all that extra time with fisetin do for your body? As it turns out, quite a bit!
Fisetin and cellular senescence
Cellular senescence is a natural part of the aging process in which cells no longer function optimally. Senescent cells can accumulate over time, affecting the day-to-day function of the healthy cells around them. Fortunately, fisetin is a senolytic compound—an ingredient that actively targets senescent cells.
In fact, fisetin is among the strongest senolytic compounds discovered so far. Fisetin helps encourage the body’s natural pathways for clearing senescent cells, which allows healthy cells to flourish. Another important aspect of cellular longevity is sirtuin function. Sirtuin proteins keep your cells performing at their best—but sirtuin activity declines with age. Fisetin has been shown in preclinical studies to encourage youthful, healthy sirtuin function.
Fisetin and brain health
Protecting your brain is another good way to live longer. A recent clinical trial showed that fisetin helped protect the delicate nerve cells in the brain, and it has also shown promise for encouraging healthy cognitive function in preclinical studies. The key is absorbing enough fisetin for it to matter.
Fisetin and glucose metabolism
Glucose metabolism is important for everything from kidney function to how your body gains or loses weight. But maintaining already-healthy blood sugar can get harder as we get older. Studies indicate that fisetin acts as a kind of metabolism control switch, which may help your body maintain healthy glucose levels already within normal range. This in turn helps promote kidney health and vision health.
Non-GMO |
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- KEEP OUT OF REACH OF CHILDREN
- DO NOT EXCEED RECOMMENDED DOSE
- Do not purchase if outer seal is broken or damaged.
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Immune & cardiovascular health, oxidative stress, bioavailability
Bio-Quercetin® uses a quercetin combined with fibers from fenugreek seeds to increase bioavailability. The result: a science-based quercetin supplement that far outclasses standard quercetin formulations.
What Is Bio-Quercetin?
Quercetin encourages heart health and supports a healthy immune response. But like many phytonutrients, quercetin isn’t easy to absorb. So we combined quercetin with fenugreek seed fibers to enhance "free" quercetin up to 18x (with up to 62x better total bioavailability) over standard quercetin formulas.
Looking for a quercetin supplement? Take the one that’s up to 62x more bioavailable. Now that’s a healthy decision!
Bio-Quercetin® Benefits
- Delivers 18x more bioavailable free quercetin (up to 62x better total bioavailability)*
- Promotes immune, cardiovascular & endothelial health
- Helps protect against oxidative stress & supports a healthy inflammatory response
*Than unformulated quercetin formulas
Why Should I Supplement With Bio-Quercetin?
- Encourage healthy cellular function
- Support cardiovascular & endothelial health
- Quercetin inhibits oxidative stress & helps promote a healthy inflammatory response
Clinically Studied for Greater Bioavailability
In a randomized clinical study, researchers compared the formulated Bio-Quercetin to unformulated quercetin. They found that the quercetin formulated with fenugreek fibers led to serum levels of total quercetin up to 62 times higher than unformulated quercetin, and 18 times higher levels of free (unconjugated) quercetin.1
Supports cardiovascular and endothelial health
Quercetin promotes both cardiovascular and endothelial health and helps maintain healthy blood pressure already within the normal range. Quercetin is also a potent inhibitor of oxidative stress and helps promote a healthy inflammatory response.
Promotes a Healthy Immune Response
Quercetin promotes a healthy immune response in the face of seasonal immune challenges. In a randomized clinical trial, quercetin encouraged a healthy immune response in physically fit older adults.
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- KEEP OUT OF REACH OF CHILDREN
- DO NOT EXCEED RECOMMENDED DOSE
- Do not purchase if outer seal is broken or damaged.
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
SYSTEMIC ENZYME FOR DIGESTIVE SUPPORT
Bio-Zyme® is a systemic enzyme providing pancreatic enzyme complex.* Bio-Zyme contains undiluted pancreatic extract for digestive support.
DIRECTIONS
Bio-Zyme® Directions and/or Dosage To relieve occasional muscle soreness and discomfort due to overexertion and exercise*, adults take 2 tablets three times a day between meals. To support optimal digestion*, take 2 tablets up to three times a day, before each meal. Not formulated for children.
Warning Caution: If you are pregnant, nursing, have diabetes or if you are taking any medications, consult a healthcare professional before use. Keep out of reach of children. Safety sealed with inner seal. Do not use if seal is broken or missing. Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.
FAQS
Q: What is the difference between plant enzymes and animal enzymes?
A: Animal enzymes, particularly porcine derived enzymes, closely resemble human digestive enzymes. For that reason, many experts believe that animal enzymes are very effective. In general, animal enzymes are more sensitive to pH extremes. To compensate for this pH sensitivity, many of the animal enzyme formulas contain bicarbonates to protect the enzymes from stomach acid. Plant enzymes are derived from fungal or botanical sources. These enzymes are able to survive a broad range of pH levels throughout the gastrointestinal tract. Plant enzymes also allow us to provide digestion support products to our vegetarian customers.
Q: On the Bio-Zyme® label, what does 10X mean?
A:The designation "X" means "times" – therefore, "10x" means "10 times". The pancreatic enzymes in Bio-Zyme® are 10 times more potent that the expected minimum activity. The minimum activity was set by the United States Pharmacopoeia, a scientific body which establishes standards for prescription medications and some dietary supplements.
Q: Should I take Bio-Zyme® with meals or between meals?
A: To relieve muscle soreness and discomfort due to overexertion and exercise, take 2 tablets two to three times a day between meals. To support optimal digestion, take 2 tablets before each meal.*
Q: Why isn't the Bio-Zyme® tablet enteric coated?
A: Enteric-coating is not necessary as the enzymes are buffered with bicarbonate to protect them from stomach acid.
Q: What do you do to ensure the safety of glandular extracts?
A: All glandulars used in our products are produced in facilities that are registered and inspected by the United States Department of Agriculture. In addition to federal inspections, all of the glandular materials received at our facility are also subjected to numerous laboratory analyses, including tests for contamination with yeast, molds, and bacteria such as E.coli, Salmonella, and Staphylococcus.
Q: According to the Bio-Zyme® label, the lysozyme enzyme is derived from eggs. Can someone with an egg allergy safely take this product?
A: The lysozyme found in Bio-Zyme® is obtained from the egg white. While 10 mg (the amount of lysozyme per serving) is a small amount, some people with allergies react to the very smallest quantity of the allergen. For sensitive individuals, Similase can be suggested as an egg-free alternative.
| INGREDIENTS | Amount / Serving | %DV |
|---|---|---|
| Serving Size: 2 tablets | ||
| Pancreatic enzymes USP units of activity: | ||
| Amylase | 81,250 USP | ** |
| Protease | 81,250 USP | ** |
| Lipase | 6,500 USP | ** |
| Total Pancreatic Enzymes | 361mg | ** |
| Trypsin | 75mg | ** |
| Papain | 50mg | ** |
| Bromelain | 16mg | ** |
| Amylase | 10mg | ** |
| Lipase | 10mg | ** |
| Chymotrypsin | 2mg | ** |
Daily Value (DV) not established
†Percent daily value is based on a 2000 calorie diet
Other Ingredients: cellulose, potassium bicarbonate, lactose monohydrate, stearic acid, hypromellose, sodium croscarmellose, magnesium stearate, glycerin, silica
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BIOACTIVE COLLAGEN COMPLEX Bone and Joint Support** offers a clinically-backed, comprehensive approach to bone and joint health** Developed with a team of leading nutrition experts, this daily supplement is made with clinically-demonstrated amounts of functional ingredients, including FORTIBONE®, FORTIGEL® , PureWay-C™, and Mobilee® , designed to increase bone mineral density**1 and help maintain optimal joint moblity**2.
Key Features (per serving)
10g bioactive collagen peptides (from FORTIBONE® & FORTIGEL®)
100%DV PureWay-C™ Liposomal Vitamin C
105%DV Vitamin D3 (as cholecalciferol)
100%DV Vitamin K2 (as menaquinone-7) 80mg Chicken Comb Extract Mobilee® (standardized to contain 40mg hyaluronic acid)Certifications & Dietary Callouts
made without gluten, made without dairy, made with non-GMO ingredientsBenefits
- Increases bone mineral density and collagen formation**1
- Helps maintain optimal joint mobility**2
- Promotes collagen synthesis**
- Supports endogenous synthesis of hyaluronic acid**** These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
1 After 12 month supplementation with FORTIBONE®
2 After 12 week supplementation with FORTIGEL®
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How to Use
Mix one scoop in 8 oz. of liquid—like coffee, water or smoothie—and consume every day.Caution
This product is manufactured in a facility that processes milk, fish and tree nuts.
Storage
Storage Information: Store in a cool, dry place.
Do not use if safety seal is broken or missing.
Be all that you can “B” with an energized body and sharp mind. Our BioActive Complete B-Complex offers the full spectrum of vitamin B benefits, in a highly absorbable formula.
What Is BioActive Complete B-Complex?
Are you getting enough vitamin B? There are more forms of it than you may think, and each plays a different role. So it’s important to get a wide spectrum of the vitamin B family, every day. BioActive Complete B-Complex is made with the biologically active forms of each nutrient, optimizing absorption and giving your body what it needs to thrive.
Getting your Bs doesn’t have to be difficult. Get the biologically active forms of these vitamins you need to thrive.
BioActive Complete B-Complex Benefits
- Boosts energy production and promotes a healthy metabolism
- Encourages brain, cellular and organ health
- More biologically active so your body can use each nutrient more effectively
Why we use bioactive B vitamins
The B vitamin family supports the proper assimilation of nutrients and energy from the foods you eat. But before your body can use B vitamins, it must first convert them into their biologically active forms. That’s why we created BioActive Complete B-Complex—it combines the active forms of each of the eight B vitamins, so your body can skip a step and directly access the many health benefits these essential nutrients offer.
100 mg of vitamin B1 (thiamine)—Thiamine helps convert carbohydrates into usable energy.1 It also supports healthy nervous system function and production of both RNA and DNA. 2,3
75 mg of vitamin B2 (riboflavin)—Our formula contains vitamin B2 in the form of riboflavin and riboflavin-5’-phosphate, the active form of the nutrient. The body converts riboflavin to its riboflavin-5’-phosphate form, which the body then uses for energy production.4
100 mg of vitamin B3 (niacin)—Niacin supports healthy energy transfer reactions. It affects healthy metabolism of glucose, fat and alcohol. Plus, it supports healthy cholesterol levels for those already within normal range.5
500 mg of vitamin B5 (pantothenic acid)—Vitamin B5 is an essential cofactor in energy metabolism,6 hormone synthesis, neurotransmitter signaling and the oxidation of fatty acids.7
100 mg of vitamin B6 (pyridoxine HCI and pyridoxal 5’-phosphate)—Vitamin B6 participates in amino acid and lipid metabolism. Along with B5, it is a cofactor in neurotransmitter and hemoglobin synthesis. B6 is also involved in gluconeogenesis, the formation of glucose from non-carbohydrate sources. And while pyridoxine must be converted by the liver into pyridoxal 5’-phosphate before it can be utilized, our formula includes this nutrient from the start.8,9
1,000 mcg of biotin—This B vitamin is a cofactor of enzymes involved in fatty acid metabolism. It’s also essential to maintaining metabolic homeostasis, or the balance between your body’s many chemical pathways and processes.10
680 mcg of folate (5-MTHF)—Folate helps maintain red blood cell production within normal range and also helps the body make and maintain healthy DNA.11 The active form of folate is up to seven times more bioavailable than folic acid. Plus, BioActive Complete B-Complex delivers 50 mg of para-aminobenzoic acid (or PABA) to encourage folic acid synthesis.
300 mcg of vitamin B12 (methylcobalamin)—Vitamin B12 affects nerve cell growth and supports heart health by helping to maintain healthy homocysteine levels already within normal range.4-7 Methylcobalamin B12 is the form that is biologically active in the brain.12-14
100 mg of inositol—This B vitamin is a primary component of phospholipids that make up cellular membranes. Inositol is essential for calcium and insulin signal transduction—the unique chemical reactions that occur when molecules attach to a receptor on a cell’s membrane.15,16
BioActive Complete B-Complex provides all the daily vitamin B benefits the body needs. It’s the perfect complement to any well-rounded nutritional regimen.
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•NE (niacin equivalents). °DFE (dietary folate equivalents) Non-GMO |
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- KEEP OUT OF REACH OF CHILDREN
- DO NOT EXCEED RECOMMENDED DOSE
- Do not purchase if outer seal is broken or damaged.
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Promotes heart, brain & GI tract health
Our BioActive Folate & Vitamin B12 includes biologically active forms of folate and vitamin B12 to promote heart, brain and GI tract health.
What Is BioActive Folate & Vitamin B12?
BioActive Folate & Vitamin B12 supports the heart, brain, GI tract and more because its capsules contain the clinically studied, biologically active forms of folate (as 5-methyltetrahydrofolate) and vitamin B12 (as methylcobalamin).
BioActive Folate & Vitamin B12 capsules use clinically studied forms of folate and vitamin B12 to maximize benefits.
BioActive Folate & Vitamin B12 Benefits
- Supports heart health & already normal homocysteine levels
- Promotes nerve cell growth, brain health, cognition & metabolism
- Helps maintain a healthy GI tract
- Supports a healthy immune system & nervous system function
- Helps maintain production of red blood cells within normal range
The Variety of Vitamin B
The vitamin B family is much more complex than most people realize, and it also offers numerous health benefits. With this in mind, Life Extension formulated BioActive Folate & Vitamin B12 with some of the most biologically active forms of folate and vitamin B12 to maximize benefits for the heart, brain and GI tract.
More facts about BioActive Folate & Vitamin B12
BioActive Folate & Vitamin B12 capsules contain the biologically active forms of folate (as 5-methyltetrahydrofolate) and vitamin B12 (as methylcobalamin).
5-methyltetrahydrofolate (5-MTHF) is the metabolically active form of folic acid. It’s the only form of folate used directly by the body and does not require metabolic conversion or activation. 5-MTHF is up to seven times more bioavailable than folic acid.1 5-MTHF can cross the blood-brain barrier, which allows 5-MTHF specifically to benefit the neurological system.
Methylcobalamin is the bioactive form of B12 that is readily utilized in the body and central nervous system.
What Folate Does for the Body
Folate is a member of the B-complex family. It is found in abundance in leafy green vegetables. Folate participates in an enzymatic reaction that synthesizes DNA needed for cell growth and new cell formation, and it helps convert vitamin B12 to one of its bioactive forms.
Folate provides many health benefits, including helping to promote healthy DNA function, maintaining already normal homocysteine levels for heart health, promoting healthier skin, and helping to maintain a healthy GI tract and immune system. It also maintains healthy endothelial function and may improve mild memory loss associated with aging.
Optimal levels of folate are necessary for healthy cell division and protein synthesis and are especially important for the maintenance of a healthy GI tract. Chronic use of medications such as aspirin in therapeutic doses and antacids can interfere with the metabolism of folate.
The Impact of Vitamin B12
Vitamin B12 is found in foods of animal origin, including dairy products and eggs. Thus, vegetarians are more susceptible to a dietary deficiency of this important nutrient. With aging, absorption of vitamin B12 from dietary sources typically declines.
Benefits of vitamin B12 include supporting brain health and cognition, and supporting heart health by regenerating the amino acid methionine, which helps maintain healthy homocysteine levels. B12 also helps enhance methylation and promote nerve cell growth, brain health, cognition and metabolism. And when combined with folate, it helps maintain the production of red blood cells (erythropoiesis) within normal range.
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- KEEP OUT OF REACH OF CHILDREN
- DO NOT EXCEED RECOMMENDED DOSE
- Do not purchase if outer seal is broken or damaged.
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
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