About Life Extension
Life Extension is a privately owned vitamin and supplement company founded in 1980 and headquartered in Fort Lauderdale, Florida.
The brand offers a broad range of science-based supplements, vitamins, minerals, antioxidants, probiotics, specialty formulas, and wellness products across many health categories.
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Promotes Healthy Homocysteine Levels
Our innovative formula helps support and maintain already-healthy homocysteine levels to support cardiovascular health.
What Is TMG?
Trimethylglycine (TMG) has been linked to heart health by supporting already-healthy homocysteine levels to promote healthy cardiovascular function. By having a positive impact on your homocysteine levels, TMG helps you stay healthy by supporting multiple systems throughout your body.
TMG (also called glycine betaine) has been associated with beneficial effects on liver function and cardiovascular health.
TMG Powder Benefits
- Promotes healthy homocysteine levels already within normal range
- Helps inhibit inflammatory factors to encourage cardiovascular health
- Supports already-healthy blood pressure levels
- Encourages whole-body health
- Helps maintain healthy mitochondrial function
Over 50 Years of Research
Trimethylglycine has been known as a heart-healthy amino acid compound since the 1950s. That’s more than 50 years of scientific research to rely upon.
Trimethylglycine (TMG) is also called glycine betaine, but the name trimethylglycine signifies that it has three methyl groups attached to each molecule of glycine. Wheat bran is the main dietary source of TMG, with smaller amounts available in other cereal grains. TMG can also be made in the body from choline, an essential nutrient found in eggs, soybeans and many other foods.
TMG was found to be beneficial to heart health in the 1950s. Like some of the B vitamins (B6, B12 and folate), TMG is a methyl donor, providing extra methyl groups to hasten the conversion of homocysteine back to methionine. When a TMG methyl group is donated to a molecule of homocysteine, it converts it to the non-toxic amino acid, methionine.
The role of TMG in healthy homocysteine metabolism is even more important when B vitamin levels are low Some evidence suggests TMG may be more efficient at regulating homocysteine levels than folate. 9 Research showing TMG's ability to promote healthy levels of homocysteine already within normal range, alone or in conjunction with other nutrients, confirms its status as an important nutrient for cardiovascular and overall health.
TMG has been associated with healthy blood pressure and mitochondrial function, and has been found to be linked to cardiovascular health. TMG has also been found to promote healthy liver function. Studies show TMG can support a healthy inflammatory response by inhibiting expression of NFkappaB, TNF-alpha, and other inflammatory proteins, which may partially explain its positive impacts.14 Because intestinal microbes can make various by-products from TMG, the health of the gut microbiome influences the effects of TMG in the body.
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- KEEP OUT OF REACH OF CHILDREN
- DO NOT EXCEED RECOMMENDED DOSE
- Do not purchase if outer seal is broken or damaged.
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Supports healthy levels of this essential nutrient for thyroid health and beyond
Iodine is an essential, health-promoting trace element. Its primary biological role lies in supporting the production of thyroid hormones. Sea-Iodine™ provides 1,000 mcg of this essential element.
What Is Sea Iodine?
Iodine is a health-promoting trace element essential for life and usually ingested by consuming table salt. But many people avoid salt for health reasons. Sea-Iodine™ provides 1,000 mcg of this essential element, without upping your salt intake. Promote thyroid health and beyond with Sea-Iodine™.
Sea-Iodine™ uses ingredients harvested from a blend of organic marine algae to support healthy iodine levels.
Sea-Iodine™ Benefits
- Essential for thyroid health support
- Supports healthy iodine levels, without salt
- Convenient way to get your daily iodine intake
Trace Element Essential For Life
Iodine supports the production of two important thyroid hormones, triiodothyronine (T3) and thyroxine (T4). A healthy thyroid gland not only acts as your body’s thermostat, but it’s also one of the major maintainers of metabolism, including supporting fat burning for energy. Sea-Iodine™ proprietary formula helps health-conscious individuals support optimal iodine levels, without the salt.
Important for thyroid health support
Iodine is a health-promoting trace element essential for life. Its primary biological role lies in the production of the thyroid hormones triiodothyronine (T3) and thyroxine (T4).1 T4 and T3 contain four and three atoms of iodine per molecule, respectively. The thyroid gland actively absorbs iodide from the blood to make and release these hormones into the blood.
Get your iodine, without the salt
For decades, Americans have been told to avoid table salt. But when iodized table salt is reduced, people can unknowingly lower their iodine intake to suboptimal levels.
The good news is that you can avoid iodized table salt without sacrificing the health benefits of iodine. Sea-Iodine™ is a low-cost proprietary formula that health-conscious individuals can take each day to support optimal iodine levels. Using ingredients harvested from a blend of organic marine algae, Sea-Iodine™ brings you the health of the sea while avoiding excessive salt intake. The algae found in Sea-Iodine™ provide you with over 667% of the Recommended Daily Value of iodine.
Abundant in sea vegetation
Iodine happens to be found abundantly in sea vegetables and plants. In areas where no marine foods are eaten, people often have lower iodine levels. For this reason, U.S. commercial salt makers have long added iodine to deliver this key ingredient to your diet. However, we now know the concerns associated with eating too much table salt, which resurrects the dilemma of where to get healthy sources of iodine.
Ironically, health-conscious people are often the most likely to have low iodine levels. One reason is that athletes and people engaged in heavy physical effort deplete their healthy stores of this trace mineral through perspiration. Vegetarians and vegans also have a substantially greater likelihood of low levels of iodine than those who eat animal products. One study demonstrated iodine deficiency in 25% of vegetarians and an incredible 80% of vegans.
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If you have a thyroid condition or are taking antithyroid medications, do not use without consulting your healthcare practitioner. |
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- KEEP OUT OF REACH OF CHILDREN
- DO NOT EXCEED RECOMMENDED DOSE
- Do not purchase if outer seal is broken or damaged.
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Get the support of healthy omega-6 fatty acids and promote a healthy inflammatory response with our concentrated Mega GLA formula, which is enhanced with sesame lignans to boost effectiveness.
What Is Mega GLA Sesame Lignans?
Gamma-linolenic acid (GLA) is the precursor to the biologically active DGLA (dihomo-gamma linolenic acid), which has numerous health benefits. We’ve added sesame lignans to our formula to boost borage oil’s beneficial effects and inhibit GLA’s conversion into inflammatory factors like arachidonic acid, further supporting whole body health.
Enhancing our GLA supplement with sesame lignans enables GLA to work much better in the body, for greater health benefits.
Mega GLA Sesame Lignans Benefits
- Promotes a healthy inflammatory response
- Supports the formation of prostaglandin E1, Which promotes vascular health and more
- Encourages healthy levels of biologically active dihomo-gamma-linolenic acid
Getting the Right Omega-6
Not all omega-6 fatty acids are of equal value. Arachidonic acid (AA), for instance, is the precursor of inflammatory factors like prostaglandin E2 (PGE2), thromboxane A2, and leukotriene B4. In contrast, gamma-linolenic acid (GLA) plays a beneficial role in healthy prostaglandin (PGE1) formation and inhibiting inflammatory factors, both of which promote vascular as well as whole-body health.
Omega-6 fatty acids like linoleic acid are well-supplied in the diet by meat and vegetable oils. But some omega-6s can contribute to the production of inflammatory compounds such as prostaglandin E2 (PGE2), thromboxane A2 and leukotriene B4 (LTB4).
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If you are taking anticoagulant or antiplatelet medications, or have a bleeding disorder, consult your healthcare provider before taking this product. |
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- KEEP OUT OF REACH OF CHILDREN
- DO NOT EXCEED RECOMMENDED DOSE
- Do not purchase if outer seal is broken or damaged.
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Discomfort Relief provides the benefits of 600 mg of PEA (palmitoylethanolamide) in a convenient, berry-flavored chewable tablet.
What Is Discomfort Relief?
PEA (palmitoylethanolamide) is a compound naturally produced by your body. We’ve packed 600 mg of PEA into a convenient, chewable tablet so you can live comfortably.
An estimated 144 million U.S. adults report having experienced some kind of pain in the previous three months.
Discomfort Relief Benefits
- Inhibits minor pain and discomfort
- Delivers convenience in berry-flavored chewables
Occasional, Minor Discomfort? We’ve Got You Covered
Discomfort Relief packs 600 mg of PEA (palmitoylethanolamide) into a convenient, chewable tablet that has been clinically studied to relieve occasional minor pain.
Discomfort Relief is a chewable supplement that relieves occasional minor pain. PEA (palmitoylethanolamide) is a compound naturally produced by your body. Now, we’ve packed 600 mg of PEA into a convenient, chewable tablet.
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- KEEP OUT OF REACH OF CHILDREN
- DO NOT EXCEED RECOMMENDED DOSE
- Do not purchase if outer seal is broken or damaged.
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
PEA inhibits inflammatory factors to support nerve cell health. Honokiol encourages healthy levels of calming neurotransmitters in the brain. Together, they help alleviate minor discomfort.
What Is ComfortMAX?
ComfortMAX™ delivers two potent ingredients: palmitoylethanolamide (PEA) and honokiol, a compound derived from Magnolia bark. By promoting nerve comfort in two separate yet complementary ways, the ingredients in ComfortMAX™ help to inhibit nerve discomfort.
The reasons for physical discomfort vary, but the way we experience that discomfort doesn't. That's why we’ve created ComfortMAX™.
ComfortMAX™ Benefits
- Dual-action formula helps alleviate minor nerve discomfort
- Helps you stay comfortable throughout the day
- Provides morning and nighttime doses for around-the-clock support
The How & Why Behind ComfortMAX™
By inhibiting inflammatory compounds to promote nerve health and encouraging healthy neurotransmitter levels in your brain, ComfortMAX™ helps to reduce discomfort. Formulated to be taken twice a day, one tablet in the morning and one tablet at night right before bed, it helps with relieving discomfort—day and night.
According to the National Institutes of Health, nearly 25 million Americans experience daily discomfort. This kind of discomfort can affect mood, mobility and quality of life. The reasons for physical discomfort vary, but the way we experience that discomfort doesn’t: Our peripheral nerves are responsible for delivering sensory information (an itch, temperature change, physical pressure, etc.) to the brain. And that’s where ComfortMAX™ comes in.
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Non-GMO Dosage and Use
The blue PM tablet may cause mild sedation in some people. Take at bedtime. |
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- KEEP OUT OF REACH OF CHILDREN
- DO NOT EXCEED RECOMMENDED DOSE
- Do not purchase if outer seal is broken or damaged.
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
What Is One-Per-Day Multivitamin?
Many of us take a multivitamin, but the individual nutrient amounts are usually small. Our One-Per-Day multivitamin provides a full spectrum of essential vitamins, minerals and other nutrients that meet or exceed the Recommended Dietary Allowance (RDA) for nearly every ingredient where an RDA exists—all in a once-daily tablet.
Our high-potency One-Per-Day formula provides more of the essential vitamins, minerals and other nutrients the body needs.
One-Per-Day Multivitamin Benefits
- #1 Rated Multivitamin from ConsumerLabs.com†
- Supports cellular health, blood vessel health, healthy immune function & more
- Promotes both heart & brain health
- Helps quench free radical activity
Our soy-free One-Per-Day Tablets contain the bioactive form of the B-vitamin folate 5-MTHF, zinc citrate, the mixed tocopherol form of vitamin E and more. Get the most out of your multivitamin with Life Extension One-Per-Day Tablets.
Marigold extract—Standardized for both trans-lutein and trans-zeaxanthin, the marigold extract in our One-Per-Day formula promotes ocular health and helps inhibit oxidative stress.
Vitamin D for healthy minds and bodies
We all know vitamin D supports bone health. But vitamin D also promotes healthy cell division, supports immune system health and more.2,3 Because vitamin D insufficiency is very common, our One-Per-Day multivitamin delivers 50 mcg of vitamin D3 with every serving.
Vitamin C for immune health, arterial health and more
Vitamin C is famously associated with immune system health, an effect that may result from its ability to scavenge free radicals and protect against oxidative stress, as well its stimulation of the production and function of white blood cells.4-6 Additionally, vitamin C is vital to collagen formation, the connective tissue found throughout healthy arterial walls, skin, bones and teeth.5 Our One-Per-Day formula delivers 470 mg of vitamin C per serving.
B vitamins help maintain youthful metabolism
Your body needs B vitamins to release energy stored in carbohydrates, fats and proteins — energy your cells use to carry out their daily functions. But there’s more than one “vitamin B.” And because they are metabolically codependent, B vitamins work together to keep you healthy. That’s why our formula contains readily metabolized forms of vitamin B1, riboflavin (B2), vitamin B12, vitamin B6 and more.
Bioactive 5-MTHF Folate
Our One-Per-Day formula now contains 5-methyltetrahydrofolate (5-MTHF), a form of folate that may be up to seven times more bioavailable than folic acid.7 This form of folate requires no conversion to become metabolically active, which is important as research shows that many people lack the robust activity of the enzyme that’s necessary to convert folic acid to 5-MTHF.8
Mixed vitamin E tocopherols
Most commercial multivitamins provide only the alpha-tocopherol form of vitamin E, but there are four tocopherols. One-Per-Day provides all four. For biomarkers of oxidative stress, evidence shows that combining alpha- and gamma-tocopherols is better than taking either nutrient alone.9 Our formula provides more than 80 mg of mixed alpha, beta, delta and gamma tocopherols.
High-potency minerals, antioxidants and extracts
A multivitamin is not complete without the minerals and other nutrients essential to healthy living. Our One-Per-Day formula provides 10 times more biotin and twice as much zinc as Centrum® Silver® Adults 50+. Our formula also delivers 100 mg of magnesium and 150 mcg of iodine, as well as trace minerals like manganese and boron.
Alpha-lipoic acid—Alpha-lipoic acid is a potent defender against oxidative stress that promotes metabolic and nerve health and helps protect vitamin C and glutathione against damaging free radicals.11-13
Selenium—Selenium supports heart and brain health, promotes a healthy inflammatory and immune response and helps quench free radical activity.14,15 Our One-Per-Day formula has three forms of selenium (200 mcg total): SelenoExcell®, Se-methyl L-selenocysteine and sodium selenite.
Apigenin—This powerful botanical bioflavonoid is found in many fruits and vegetables.16 Apigenin helps boost the body’s healthy cellular defenses.
Crominex® 3+ biologically active chromium
Chromium helps maintain already-healthy blood sugar levels. Crominex® 3+ is a highly stable and biologically active form of chromium optimized with Capros® Indian gooseberry (amla) extract to promote endothelial health and PrimaVie® shilajit for cellular energy.1
Everyone should be taking a daily multivitamin. There’s no simpler way to ensure your body is getting the essential vitamins, minerals and nutrients you need to stay healthy and live better. But not all multivitamins are created equal, so choose Life Extension One-Per-Day Tablets.
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Individuals consuming more than 50 mcg (2000 IU)/day of vitamin D (from diet and supplements) should periodically obtain a serum 25-hydroxy vitamin D measurement. Vitamin D supplementation is not recommended for individuals with high blood calcium levels. |
- KEEP OUT OF REACH OF CHILDREN
- DO NOT EXCEED RECOMMENDED DOSE
- Do not purchase if outer seal is broken or damaged.
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Adding L-Carnitine to your supplement regimen provides a host of potential health benefits associated with aging. It starts with supporting mitochondria, which power every cell in your body.
What Is L-Carnitine?
Mitochondria, the powerhouses found within human cells, produce the energy that vital tissues need to keep us vibrant and healthy. Healthy levels of carnitine support optimum functioning of mitochondria and your body’s energy production.
Maintaining optimal mitochondrial function is important for many aspects of healthy aging.
L-Carnitine Benefits
- Helps maintain cellular metabolic activity
- Supports healthy concentration of nitric oxide, which helps support already-healthy blood pressure
- Supports the brain's natural defenses against age-related memory & cognitive decline
- Helps maintain healthy body composition
Protecting Cellular Energy
L-carnitine is an amino acid produced in your body. It plays an important role in moving fatty acids into the mitochondria of your cells. This is important, since as we age, there is a steady decline in cellular energy. The primary reason is that our mitochondria aren’t functioning properly. Healthy levels of carnitine support optimum functioning of mitochondria.
Mitochondria, the powerhouses found within human cells, produce the energy that vital tissues need to keep us vibrant and healthy. Healthy levels of carnitine support optimum functioning of mitochondria.1 The problem is that as we age, levels of carnitine decline in all our tissues, reducing cellular energy production and metabolic activity.
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- KEEP OUT OF REACH OF CHILDREN
- DO NOT EXCEED RECOMMENDED DOSE
- Do not purchase if outer seal is broken or damaged.
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Bromelain, a mixture of proteases extracted from the stem of the pineapple, inhibits inflammatory factors to support joint health. Bromelain’s fluid-regulating properties may result from its ability to inhibit inflammatory cytokine production, inhibit neutrophil migration and more.
Bromelain has to be enteric coated so that it will not be activated in the stomach and used as a digestive enzyme.
Specially-Coated Bromelain Benefits:
- Inhibits inflammation to support joint health
- Supports joint comfort & function
- Supports healthy blood viscosity
Suggested Use:
Take one (1) tablet once or twice daily on an empty stomach, or as recommended by a healthcare practitioner.
Serving Size: 1 Enteric Coated Vegetable Tablet
Amount Per Serving
Calcium … 75 mg
(as calcium carbonate)
Bromelain proteolytic enzyme extract from pineapple … 500 mg
(stem) [2400 Gelatin Digestive Units per gram]
Other ingredients: microcrystalline cellulose, maltodextrin, enteric coating (methacrylic acid copolymer dispersion NF, hydroxypropyl methylcellulose, propylene glycol), croscarmellose sodium, stearic acid, hydroxypropyl cellulose, silica, vegetable stearate.
Gluten free - Non-GMO - Vegetarian
Caution:
If you are taking anticoagulant or antiplatelet medications, or have a bleeding disorder, consult your healthcare provider before taking this product. Bromelain may increase the bioavailability of tetracylcine antibiotics.
Specially-Coated Bromelain is enteric coated to protect the bromelain from becoming active in the stomach and act as a digestive enzyme for food.
Warnings:
KEEP OUT OF REACH OF CHILDREN
DO NOT EXCEED RECOMMENDED DOSE
Do not purchase if outer seal is broken or damaged.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating
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