Microbiome Labs

MegaMucosa™ – Mucosal Barrier & Immune Support Powder, 150 g

Berry Acai Flavored
Microbiome Labs

Rebuild the Mucosal Barrier. Restore Immune Balance.

MegaMucosa™ is the first gut supplement of its kind — formulated specifically to rebuild and reinforce the intestinal mucosal barrier, a key structural and immune component of gut health. This unique powder combines serum-derived immunoglobulins, four key amino acids, and MicrobiomeX®, a clinically studied citrus bioflavonoid complex that promotes gut microbial diversity and short-chain fatty acid (SCFA) production.

Ideal for individuals with intestinal inflammation, compromised gut lining (“leaky gut”), or undergoing gut restoration protocols, MegaMucosa™ delivers essential building blocks to restore mucosal integrity and regulate immune response within the gastrointestinal tract.

Key Benefits

• Supports regeneration of the gut’s protective mucin layer

• Promotes gut barrier function and epithelial resilience

• Enhances microbial diversity and SCFA production

• Supports mucosal immune function (70% of immunity resides in the gut lining)

• Naturally flavored with berry acai, easy to mix and tolerate

• Dairy-free, casein-free, gluten-free

Science Behind MegaMucosa™

The intestinal mucosa is the first line of immune and structural defense in the gut. It's where microbes, food particles, and immune cells interact — and it's where dysfunction often begins. MegaMucosa™ addresses this critical interface by combining:

• Serum-derived immunoglobulins (ImmunoLin®) – Helps neutralize antigens, toxins, and microbial byproducts in the gut lumen, supporting immune modulation and detoxification.

• Amino Acids (L-proline, L-serine, L-threonine, L-cysteine) – Essential for mucin production and repair of epithelial cells lining the gut.

• MicrobiomeX® (Citrus bioflavonoids) – A patented blend shown to increase SCFA production and support microbial diversity and gut barrier strength.

Together, these ingredients form a foundational formula for rebuilding the mucosal layer, supporting immune function, and restoring long-term gut resilience.

Supplement Facts

Serving Size: 1 scoop (4.8 g)
Servings Per Container: 30

Other Ingredients:
Natural berry acai flavor, citric acid, stevia, malic acid, natural flavor, rebaudioside M.

Suggested Use

Ages 4 and up:

• Start with ½ scoop daily for 1 week

• Then increase to 1 scoop daily, with or without food, or as directed by your healthcare practitioner

• Mix with 16 oz or more of liquid (room temperature preferred) or into food

Children under age 4: Use only under medical supervision.

Frequently Asked Questions (FAQ)

Q: What’s the difference between MegaMucosa™ and a probiotic?
A: MegaMucosa™ doesn’t introduce new microbes — instead, it supports the physical and immune environment (the mucosal lining) where microbes live and interact with the body.

Q: Can this help with “leaky gut”?
A: Yes. The mucosal barrier is a core component of the gut lining. MegaMucosa™ provides structural nutrients to restore that barrier and reduce permeability.

Q: What does it taste like?
A: Berry acai — naturally flavored and sweetened with stevia and rebaudioside M. Most users find it pleasant and easy to mix.

Q: Can I combine it with MegaSporeBiotic™ or Mega IgG2000™?
A: Absolutely. MegaMucosa™ is part of the Microbiome Labs Total Gut Restoration protocol and is designed to work synergistically with these formulas.

Mega IgG2000™ – Advanced Immunoglobulin Support, 120 Capsules

Dairy-Free Gut and Immune System Defense

Mega IgG2000™ is a clinically studied, dairy-free immunoglobulin supplement derived from bovine serum, not colostrum. This advanced formula supports immune resilience, digestive health, and gut barrier integrity. By delivering a concentrated source of IgG, IgM, and IgA antibodies, it provides passive immune protection that helps neutralize toxins, pathogens, and inflammatory triggers within the gut.

Unlike milk-derived products, Mega IgG2000™ is free from lactose, casein, and β-lactoglobulin, making it a suitable option for those with dairy sensitivities.

Key Benefits

• Supports gut barrier integrity and mucosal immune function

• Helps neutralize LPS (lipopolysaccharides) and other endotoxins

• Promotes healthy detoxification within the GI tract

• Enhances immune system modulation without overstimulation

• Supports nutrient digestion and absorption

• Lactose-free, casein-free, and β-lactoglobulin-free

Science Behind Mega IgG2000™

Immunoglobulins are antibodies that bind to unwanted microbes and toxins in the gut, helping the body remove them safely before they can trigger immune responses. Mega IgG2000™ contains high concentrations of the three most essential types:

• IgG (Immunoglobulin G) – The most abundant antibody in the human body, responsible for long-term immune surveillance.

• IgM (Immunoglobulin M) – The first antibody produced in response to new challenges, essential for early immune response.

• IgA (Immunoglobulin A) – Plays a key role in mucosal immunity in the lungs, sinuses, and GI tract, found in saliva and tears.

Mega IgG2000™ works entirely within the gut lumen, providing immune support without entering the bloodstream. It complements probiotic and gut-repair protocols, especially in individuals with compromised gut barrier or immune imbalances.

Supplement Facts

Serving Size: 4 capsules
Servings Per Container: 30

MegaSporeBiotic™ – 100% Spore-Based Probiotic for Gut Reconditioning, Capsules

Microbiome Labs

Clinically Proven. Spore-Powered. Microbiome Reconditioning Starts Here.

MegaSporeBiotic™ is the first clinically studied, 100% spore-based probiotic supplement designed to recondition the gut microbiome, support gut barrier integrity, and promote immune homeostasis. Unlike conventional probiotics that often die before reaching the intestines, spore-forming Bacillus strains in MegaSporeBiotic™ are naturally equipped to survive digestion, colonize the gut, and restore microbial balance.

This flagship product of Microbiome Labs is shelf-stable, effective at a low dose (4 Billion CFU), and does not require refrigeration.

Key Benefits

• Clinically shown to recondition the gut and support microbial diversity

• Promotes gut lining repair and intestinal barrier integrity

• Supports immune modulation and inflammatory balance

• Enhances production of short-chain fatty acids (SCFAs), especially butyrate

• Helps maintain levels of beneficial commensal bacteria

• Survives heat, stomach acid, and bile — no refrigeration needed

• Part of the Total Gut Restoration system by Microbiome Labs

Science Behind the Strains

Each 2-capsule serving delivers 4 Billion CFU of five synergistic, spore-forming Bacillus strains:

• Bacillus indicus HU36™ – Produces antioxidants (lycopene, astaxanthin, beta-carotene) at the site of absorption

• Bacillus subtilis HU58™ – Supports immune modulation, gut lining, and vitamin K2 production

• Bacillus coagulans SC208 – Enhances protein digestion and metabolic support

• Bacillus licheniformis SL307 – Promotes mucosal immunity and digestive balance

• Bacillus clausii SC109 – Resistant to antibiotics; helps regulate immune and respiratory health

These strains are clinically validated and selected for their ability to support keystone gut species and SCFA production — both essential for optimal health.

Supplement Facts

Serving Size: 2 capsules
Servings Per Container: 30
Probiotic Content: 4 Billion CFU
Total Active Blend: 295 mg

Other Ingredients: Cellulose, vegetable capsule (cellulose and water)
Free from: dairy, gluten, soy, GMOs, artificial colors or preservatives

Suggested Use

Ages 5+:

• Week 1: Take 1 capsule every other day

• Week 2: Take 1 capsule daily

• Week 3 onward: Take 2 capsules daily

Children under 5: Use only under medical supervision.
Can be taken with or without food. No refrigeration required.

Frequently Asked Questions (FAQ)

Q: What makes MegaSporeBiotic™ different from regular probiotics?
A: It contains only spore-based Bacillus strains, which survive digestion, colonize the gut, and recondition the microbiome — unlike typical Lactobacillus or Bifidobacterium strains that often degrade in the stomach.

Q: Is 4 Billion CFU enough?
A: Yes. Spore-based probiotics are highly potent. Clinical trials show 4 Billion CFU is effective for gut restoration and immune modulation.

Q: Can I take it with antibiotics?
A: Yes. Unlike many probiotics, Bacillus spores are resistant to most antibiotics, making this an excellent companion during or after antibiotic use.

Q: Should I take this with food?
A: It can be taken with or without food, but some people prefer taking it with meals for better tolerance during the initial adjustment period.

MegaPre™ – Precision Prebiotic Powder, 5.5 oz (144.5 g)

Microbiome Labs

Clinically Targeted Prebiotic to Restore Keystone Gut Bacteria

MegaPre™ is a cutting-edge Precision Prebiotic™ powder that selectively nourishes beneficial gut bacteria — without feeding opportunistic microbes. Unlike general fiber products, MegaPre™ contains clinically tested oligosaccharides and organic kiwifruit powder that promote the growth of keystone species like Akkermansia muciniphila, Faecalibacterium prausnitzii, and Bifidobacteria. These bacteria play a foundational role in gut barrier integrity, immune regulation, and short-chain fatty acid (SCFA) production.

This 5.5 oz jar contains 30 servings of unflavored, mixable powder — ideal for daily gut support and easy integration into Total Gut Restoration protocols.

Key Benefits

• Selectively feeds critical keystone bacteria (not broad-spectrum)

• Enhances microbial diversity and butyrate production

• Supports healthy gut lining and mucosal immunity

• Works synergistically with MegaSporeBiotic™

• Easy-to-mix, unflavored formula for customizable use

• Gluten-free, non-GMO, no artificial ingredients

Science Behind MegaPre™

Keystone species are essential for gut health, but modern lifestyles (processed foods, antibiotics, stress) often deplete them. MegaPre™ helps rebuild this foundation through a proprietary blend of:

• Galactooligosaccharides (Bimuno®) – Shown to support Bifidobacteria and enhance SCFA production

• Xylooligosaccharides (PreticX®) – Clinically proven to improve microbial diversity and support bowel regularity

• Organic Kiwifruit Powder (Livaux® and ACTAZIN®) – Rich in polyphenols and fiber to support gut motility and microbial balance

Together, these ingredients provide targeted nourishment for the microbiome — without causing bloating or feeding unwanted bacteria.

Supplement Facts

Serving Size: 1 scoop (4.8 g)
Servings Per Container: 30
Net Weight: 5.5 oz (144.6 g)

Other Ingredients:
None. Unflavored. Free of sweeteners, colors, and artificial additives.
Contains: milk (from lactose-derived GOS).
(Dairy-free version available separately.)

Suggested Use

Ages 4 and up:

• Start with ½ scoop per day during the first week

• Increase to 1 scoop daily, or as directed by your healthcare provider

• Mix into 8–12 oz of room temperature water, smoothie, or non-hot liquid

Children under 4: Use only under medical supervision.

Frequently Asked Questions (FAQ)

Q: Is MegaPre™ a fiber supplement?
A: Not exactly. While it contains fiber, it's a targeted prebiotic designed to support specific beneficial microbes rather than general digestion.

Q: What does it taste like?
A: It’s unflavored and mixes well with water, smoothies, or juice. No sweetness or added flavor.

Q: Can I take it with MegaSporeBiotic™?
A: Yes. It’s highly recommended as part of Microbiome Labs’ Total Gut Restoration protocol, supporting long-term microbial shifts.

Q: Is it suitable for people with sensitive digestion?
A: Yes. MegaPre™ is well-tolerated, even in individuals who react poorly to traditional prebiotics. Start with a half dose to assess tolerance.

RestorFlora™ – Comprehensive Gut Recovery Probiotic with Yeast & Spore-Based Bacteria, 60 Capsules

Microbiome Labs

Advanced Multi-Strain Formula for Digestive & Immune Resilience

RestorFlora™ is a broad-spectrum probiotic and gut recovery formula combining a clinically validated probiotic yeast (Saccharomyces boulardii) with three resilient spore-forming bacterial strains: Bacillus subtilis HU58™, Bacillus clausii SC-109, and Bacillus coagulans SC208. This powerful combination is designed to restore microbial balance, promote gut resilience, and support digestion and immunity — even during or after gut-disruptive events like antibiotics, food poisoning, or GI stress.

Unlike traditional probiotics that may degrade in the stomach or fail under antibiotic pressure, RestorFlora™ delivers hardy, shelf-stable strains that survive transit, colonize the gut, and maintain immune synergy.

Key Benefits

• Supports intestinal flora balance and microbiome resilience

• Helps maintain digestive comfort and motility

• Supports healthy transit time and relief from bloating, gas, cramps, diarrhea, or constipation

• Promotes gut recovery during/after gut-disrupting medications or practices

• Enhances immune system response and gut-lining integrity

• Combines yeast and bacterial strains for broader-spectrum support

• Shelf-stable, dairy-free, gluten-free, soy-free

Unique Multi-Strain Composition

Each capsule delivers a clinically studied combination of:

🦠 Saccharomyces boulardii (CNCM I-1079)

• A probiotic yeast known for use during and after antibiotic therapy

• Helps maintain intestinal barrier function and prevent overgrowth of unwanted microbes

• Extensively used to reduce the risk of antibiotic-associated diarrhea

🦠 Bacillus subtilis HU58™

• Spore-forming probiotic that resists stomach acid, activates in the intestines

• Produces key nutrients like vitamin K2 and short-chain fatty acids (SCFAs)

• Supports mucosal immunity and gut lining regeneration

🦠 Bacillus clausii (SC-109)

• Naturally antibiotic-resistant

• Helps regulate immune balance and support respiratory health

• Known to persist and colonize even under antimicrobial pressure

🦠 Bacillus coagulans (SC208)

• Assists protein digestion and carbohydrate fermentation

• Produces lactic acid to modulate gut pH

• Improves symptoms like bloating and abdominal discomfort

Supplement Facts

Serving Size: 1 capsule
Servings Per Container: 60
Probiotic Blend Total: 370 mg / 8 Billion CFU

MegaMarine™ – Clinical-Grade Omega-3 for Gut & Immune Health, 60 Softgels

Targeted Fish Oil Formulated for the Gut, Not Just the Brain

MegaMarine™ is a pharmaceutical-grade fish oil designed specifically for gut and immune health — not just general omega-3 support. It provides a potent and balanced blend of EPA, DHA, and DPA in their natural triglyceride form for optimal bioavailability. Additionally, it contains Specialized Pro-Resolving Mediators (SPMs) — powerful omega-3 derivatives that help the body resolve inflammation.

While most fish oils focus on brain or heart health, MegaMarine™ delivers the omega-3s your intestinal lining, microbiome, and immune cells need to function properly — making it ideal for individuals with compromised gut barrier, immune imbalance, or chronic inflammation.

Key Benefits

• Supports gut microbial diversity (incl. Akkermansia, Bifidobacterium, Lactobacillus)

• Promotes healthy mucosal lining and gut barrier function

• Neutralizes LPS and supports intestinal detoxification

• Aids in the resolution of inflammation via SPMs

• Improves absorption of EPA/DHA through inclusion of DPA

• Naturally flavored, clean softgel formula — no fishy aftertaste

• Certified sustainable and dolphin-safe (FOS Certified)

Science Behind MegaMarine™

Fish oil is widely known for its cardiovascular and neurological benefits — but its impact on gut health has often been overlooked. Recent studies show that omega-3s, especially EPA and DPA, help maintain the intestinal lining, reduce inflammatory signaling, and enhance microbial diversity.

EPA – Key for gut mucosal protection. Supports intestinal alkaline phosphatase, which detoxifies endotoxins like LPS and improves epithelial resilience.
DHA – Maintains phospholipid membrane fluidity in both the nervous system and the enteric nervous system of the gut.
DPA – A rare omega-3 that improves the bioavailability of EPA and DHA and helps modulate the COX inflammatory pathway.
SPMs (Specialized Pro-Resolving Mediators) – End-stage omega-3 metabolites that actively help the immune system resolve inflammation. Most people underproduce them due to stress, poor diet, or genetic limitations. MegaMarine™ includes SPMs directly in the formula.

Together, these components make MegaMarine™ one of the most complete omega-3 products available — engineered specifically for the needs of the gastrointestinal system.

Supplement Facts

Serving Size: 2 softgels
Servings Per Container: 30

MegaMucosa™ – Mucosal Barrier & Immune Support, 180 Capsules

Microbiome Labs

Targeted Gut Lining Support in Convenient Capsule Format

MegaMucosa™ Capsules deliver the same clinically backed formula as the MegaMucosa™ powder — now in an easy-to-dose capsule form. This advanced supplement is designed to rebuild the mucosal lining of the intestines, support gut barrier function, and modulate mucosal immune activity. It combines dairy-free immunoglobulins, four key amino acids, and the citrus polyphenol complex MicrobiomeX®, all selected for their proven effects on intestinal health and microbial diversity.

This capsule version is ideal for individuals who prefer tasteless, easy-to-swallow formats with precise dosing.

Key Benefits

• Rebuilds and strengthens the mucosal barrier

• Promotes gut barrier integrity and epithelial repair

• Supports microbial diversity and short-chain fatty acid (SCFA) production

• Enhances mucosal immune system function

• Convenient capsule form — no mixing or flavoring

• Dairy-free, gluten-free, and free of artificial additives

Science Behind MegaMucosa™

The gut mucosa plays a vital role in immune regulation, microbial balance, and nutrient absorption. MegaMucosa™ targets this critical interface with a powerful blend of:

• Serum-Derived Immunoglobulins (ImmunoLin®) – Neutralize toxins, bind microbial antigens, and reduce inflammation in the gut lumen.

• L-Proline, L-Serine, L-Threonine, L-Cysteine – Four amino acids essential for mucin production and epithelial cell repair.

• MicrobiomeX® (Citrus Bioflavonoids) – Supports microbial balance, boosts SCFA production, and helps protect gut lining integrity.

The synergy between these components makes MegaMucosa™ a foundational supplement for individuals with leaky gut, chronic inflammation, immune dysregulation, or recovering from antibiotic or gut-damaging protocols.

Supplement Facts

Serving Size: 6 capsules
Servings Per Container: 30

Other Ingredients:
Vegetable capsule (cellulose and water), cellulose, magnesium stearate.

Suggested Use

Ages 4 and up:

• Start with 3 capsules daily (with or without food) for the first week

• Then increase to 6 capsules daily, or as directed by your healthcare practitioner

Children under 4: Use only under the guidance of a healthcare provider.

Frequently Asked Questions (FAQ)

Q: Is this the same formula as the MegaMucosa™ powder or sticks?
A: Yes. All forms contain the same clinically validated ingredients and dosages. The capsule version offers a flavorless, convenient alternative to the powdered forms.

Q: What’s the benefit of taking it in capsule form?
A: Capsules are ideal for those sensitive to taste or needing portability and precision. No mixing required.

Q: Can MegaMucosa™ help with gut permeability or chronic GI inflammation?
A: Yes. It is specifically formulated to rebuild the intestinal mucosal barrier and reduce gut-derived immune activation.

Q: Can it be used alongside probiotics?
A: Absolutely. MegaMucosa™ complements probiotic protocols and is part of the Total Gut Restoration system from Microbiome Labs.

Mega IgG2000™ Powder – Dairy-Free Immunoglobulin Concentrate, 60 g

Immune and Gut Barrier Support in a Pure, Powdered Form

Mega IgG2000™ Powder is a purified, dairy-free immunoglobulin concentrate designed to support gut barrier function, immune regulation, and gastrointestinal detoxification. Unlike colostrum-based supplements, Mega IgG2000™ is derived from bovine serum and contains no lactose, casein, or β-lactoglobulin — making it suitable for individuals with dairy sensitivities.

This powdered version offers flexible dosing and is ideal for individuals who prefer non-capsule formats or need tailored immune and digestive support as part of their gut restoration protocol.

Key Benefits

• Supports gut barrier integrity and mucosal immune function

• Helps bind and neutralize endotoxins (such as LPS) and microbial debris

• Promotes immune balance without overstimulation

• Enhances nutrient absorption and supports healthy metabolism

• Dairy-free, casein-free, β-lactoglobulin-free

• Mixes easily into cold liquids

Immunoglobulin Profile

Mega IgG2000™ contains three key antibodies:

• IgG (Immunoglobulin G): The most abundant antibody in circulation, essential for long-term immune defense.

• IgM (Immunoglobulin M): The first line of defense against unfamiliar antigens.

• IgA (Immunoglobulin A): Found in mucosal areas (GI tract, sinuses, lungs), saliva, and tears — supports local immunity.

These immunoglobulins act within the gut lumen to capture and clear harmful substances before they can enter systemic circulation.

Supplement Facts

Serving Size: 1 scoop (2 g)
Servings Per Container: 30