HU58™ 60 capsules Microbiome Labs

HU58™ – High-Potency Bacillus subtilis Probiotic, 60 Capsules

Microbiome Labs

Targeted Gut Microbiome and Immune Support

HU58™ is a pharmaceutical-grade, single-strain probiotic supplement containing Bacillus subtilis HU58™ — a clinically studied, spore-forming bacterium known for its resilience and potent biological activity. This unique strain supports microbial balance, healthy digestion, and immune function through the production of key nutrients and health-promoting metabolites.

Unlike many conventional probiotics, HU58™ survives stomach acid and bile, reaching the intestine intact. It then germinates and begins actively modulating the gut environment. Research shows that Bacillus subtilis HU58™ produces over two dozen beneficial compounds, including vitamin K2, short-chain fatty acids (SCFAs), B vitamins, and the enzyme nattokinase.

HU58™ is especially useful as a stand-alone high-dose probiotic or as an adjunct to MegaSporeBiotic™, providing additional microbial reinforcement in individuals with more advanced or persistent gut imbalances.

Key Benefits

• Supports healthy microbial balance and diversity

• Promotes immune system regulation and GALT development

• Encourages normal digestive motility and barrier integrity

• Enhances nutrient synthesis: vitamin K2, SCFAs, B-complex vitamins

• Produces nattokinase – a fibrinolytic enzyme with circulatory benefits

• Withstands stomach acid and harsh GI conditions

• No refrigeration required

Supplement Facts

Serving Size: 2 capsules
Servings Per Container: 30

Other Ingredients:
Cellulose, vegetable capsule (cellulose and water)

Suggested Use

Adults and children age 5+:

• Week 1: Take 1 capsule daily with food

• Week 2 and beyond: Increase to 2 capsules daily with food

Children under 5: Use only under guidance of a healthcare practitioner.

HU58™ may be taken alongside MegaSporeBiotic™ or separately as needed.

Science Behind HU58™

Bacillus subtilis is a naturally occurring, spore-forming bacterium that acts as a commensal organism in the human gut. Its endospore structure allows it to withstand manufacturing, shipping, and gastrointestinal transit. Once in the intestines, it transitions into an active vegetative state, where it produces compounds that modulate immune function and suppress undesirable microbes.

Studies have shown that supplementation with Bacillus subtilis HU58™ can positively influence microbial composition, support the production of key vitamins and anti-inflammatory compounds, and help maintain digestive health during periods of stress or imbalance.

Frequently Asked Questions (FAQ)

Q: Does HU58™ require refrigeration?
A: No. Thanks to its spore-forming nature, HU58™ is shelf-stable and highly resilient.

Q: Can I take HU58™ with antibiotics?
A: Yes. HU58™ survives antibiotic exposure better than many non-spore probiotics, making it ideal during or after antibiotic therapy (consult your practitioner for personal guidance).

Q: What is the difference between HU58™ and MegaSporeBiotic™?
A: HU58™ contains only Bacillus subtilis HU58™ in a concentrated dose, while MegaSporeBiotic™ includes a blend of five Bacillus strains. HU58™ is often used to intensify or customize probiotic support.

Q: Who might benefit from HU58™?
A: HU58™ may be helpful for those with microbiome imbalance, weakened immunity, poor digestion, or as part of gut recovery protocols.