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MegaMarine 60 Softgels Microbiome Labs
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MegaMarine™ – Clinical-Grade Omega-3 for Gut & Immune Health, 60 Softgels
Targeted Fish Oil Formulated for the Gut, Not Just the Brain
MegaMarine™ is a pharmaceutical-grade fish oil designed specifically for gut and immune health — not just general omega-3 support. It provides a potent and balanced blend of EPA, DHA, and DPA in their natural triglyceride form for optimal bioavailability. Additionally, it contains Specialized Pro-Resolving Mediators (SPMs) — powerful omega-3 derivatives that help the body resolve inflammation.
While most fish oils focus on brain or heart health, MegaMarine™ delivers the omega-3s your intestinal lining, microbiome, and immune cells need to function properly — making it ideal for individuals with compromised gut barrier, immune imbalance, or chronic inflammation.
Key Benefits
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Supports gut microbial diversity (incl. Akkermansia, Bifidobacterium, Lactobacillus)
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Promotes healthy mucosal lining and gut barrier function
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Neutralizes LPS and supports intestinal detoxification
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Aids in the resolution of inflammation via SPMs
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Improves absorption of EPA/DHA through inclusion of DPA
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Naturally flavored, clean softgel formula — no fishy aftertaste
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Certified sustainable and dolphin-safe (FOS Certified)
Science Behind MegaMarine™
Fish oil is widely known for its cardiovascular and neurological benefits — but its impact on gut health has often been overlooked. Recent studies show that omega-3s, especially EPA and DPA, help maintain the intestinal lining, reduce inflammatory signaling, and enhance microbial diversity.
EPA – Key for gut mucosal protection. Supports intestinal alkaline phosphatase, which detoxifies endotoxins like LPS and improves epithelial resilience.
DHA – Maintains phospholipid membrane fluidity in both the nervous system and the enteric nervous system of the gut.
DPA – A rare omega-3 that improves the bioavailability of EPA and DHA and helps modulate the COX inflammatory pathway.
SPMs (Specialized Pro-Resolving Mediators) – End-stage omega-3 metabolites that actively help the immune system resolve inflammation. Most people underproduce them due to stress, poor diet, or genetic limitations. MegaMarine™ includes SPMs directly in the formula.
Together, these components make MegaMarine™ one of the most complete omega-3 products available — engineered specifically for the needs of the gastrointestinal system.
Supplement Facts
Serving Size: 2 softgels
Servings Per Container: 30
Nutrient | Amount per Serving |
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Total Omega-3 Fatty Acids | 1500 mg |
– EPA (Eicosapentaenoic Acid) | 850 mg |
– DHA (Docosahexaenoic Acid) | 450 mg |
– DPA (Docosapentaenoic Acid) | 100 mg |
Specialized Pro-Resolving Mediators (PRMs) | 200 mg |
Total Fat | 2.5 g (3% DV) |
Cholesterol | 10 mg (3% DV) |
Calories | 25 |
Protein | <1 g |
Other Ingredients:
Highly refined omega-3 marine oil (from anchovy, sardine, herring, mackerel, squid), natural lemon flavor, mixed tocopherols (antioxidants), capsule (bovine gelatin, glycerin, water).
Contains fish.
Suggested Use
Ages 8 and up:
Take 2 softgels daily with food, or as recommended by your healthcare practitioner.
No refrigeration required. Store in a cool, dry place.
Frequently Asked Questions (FAQ)
Q: What makes MegaMarine™ different from regular fish oils?
A: Most fish oils are formulated for heart or brain support. MegaMarine™ is specifically engineered for gut health, with a high EPA content, added DPA for bioavailability, and SPMs to promote inflammation resolution.
Q: Why are SPMs important?
A: Specialized Pro-Resolving Mediators (SPMs) help your immune system actively resolve inflammation rather than simply suppress it. MegaMarine™ includes them preformed, which bypasses conversion limitations caused by stress, genetics, or diet.
Q: Can this help with leaky gut or GI inflammation?
A: Yes. The combination of EPA, DPA, and SPMs helps support gut barrier integrity, reduce inflammatory signaling, and improve detoxification of endotoxins like LPS.
Q: Is this product sustainable?
A: Yes. MegaMarine™ is Friends of the Sea (FOS) certified, meeting strict environmental and sustainability standards, including dolphin-safe practices.